Image 1_Kaixin San Jiawei granule improves cognitive function and alleviates neuronal damage in Alzheimer’s disease via multi-component and multi-target mechanisms.tif by Wei Liu (20030)

“…In vitro, KSG mitigated Aβ_25-35-induced cytotoxicity in PC12 cells, decreased Aβ accumulation, and downregulated the expression of TNF-α and IL-1β. …”

Table 1_Regional and age-specific global trends associated with infectious diarrhea in children under 14 years old caused by pathogenic microorganisms in 2021.docx by Tuanjie Wang (6619406)

“…</p>Conclusion<p>Although the global burden of diarrhea has decreased significantly, it is still high in low-income countries and low- and medium-SDI areas, and newborns are at high risk. …”

DataSheet1_DYNLT3 overexpression induces apoptosis and inhibits cell growth and migration via inhibition of the Wnt pathway and EMT in cervical cancer.pdf by Jianan Zhang (786459)

“…Upregulation of DYNLT3 expression markedly decreased the expression of Wnt signaling pathway-related proteins (Dvl2, Dvl3, p-LRP6, Wnt3a, Wnt5a/b, Naked1, Naked2, β-catenin and C-Myc) and EMT-related proteins (N-cadherin, SOX2, OCT4, vimentin and Snail), and increased the expression of E-cadherin and Axin1. …”

Data Sheet 1_High spatial resolution gene expression profiling and characterization of neuroblasts migrating in the peri-injured cortex using photo-isolation chemistry.docx by Takuya Miyamoto (567070)

“…Experiments using primary cultured neuroblasts showed that application of TGF-β significantly decreased proliferating cells labeled with BrdU. …”

Data Sheet 1_Dendritic cells in the human vaginal mucosa can direct CD4+ T cell responses by expressing surface OX40L.pdf by HyeMee Joo (175770)

“…Neutralizing OX40L with anti-OX40L antibody significantly decreased the frequency of Th2-type CD4⁺ T cells with a reduction of CD4⁺ T cell proliferation, while increasing the frequency of IL - 10-producing CD4⁺ T cell responses. …”

Data Sheet 1_Clinical characteristics and outcome of very old (≥90 years) critically ill patients with need for intensive care after surgical intervention.docx by Jöran Lücke (14948623)

“…Background<p>Due to increasing life expectancy and decreasing morbidity, society is aging. Especially the group of very old patients (≥90 years) is currently increasing significantly. …”

Data Sheet 1_Strategies for enhancing yield and quality of forage-grain dual-purpose ratoon rice: role of first-season density and nitrogen management.docx by Yuyuan Ouyang (15350374)

“…Nutritional and safety quality varied significantly across treatments and cultivars. FY498 had high protein and low cadmium content under D1N3; CKYSM showed high starch and low cadmium under D2N3, indicating superior overall performance. …”

Data Sheet 1_KAE ameliorates LPS-mediated acute lung injury by inhibiting PANoptosis through the intracellular DNA-cGAS-STING axis.zip by Yonghu Chen (2040136)

“…</p>Results<p>KAE significantly alleviated lipopolysaccharide-induced pulmonary injury by reducing inflammatory cell infiltration, alleviating pulmonary edema, enhancing antioxidant capacity, and decreasing levels of inflammatory cytokines in mouse lung tissues. …”

Data Sheet 1_Exploratory study on the ascending pain pathway in patients with chronic neck and shoulder pain based on combined brain and spinal cord diffusion tensor imaging.docx by Zhiqiang Qiu (4603993)

“…FA values of the left STT (C2 segment, C5 segment) and right STT (C1 segment, C2 segment) were significantly decreased in bilateral cervical STTs of CNSP patients; MD values of the left STT (C1 segment, C2 segment, C5 segment) and right STT (C1 segment, C5 segment) were significantly increased (p < 0.05). …”

Additional file 2 of Single-cell profiling reveals periosteal signatures of impaired periosteal cells proliferation in a drill-hole model of type 2 diabetes by Xing Ji (3096735)

“…Statistical significance was assessed using one-way ANOVA with Sidak’s multiple comparison test. …”

Data Sheet 1_Assessing the disease burden of lower respiratory infections attributable to particulate matter pollution: trends from 1990 to 2021 and projections for 2022-2050.pdf by Erman Wu (19021269)

“…Children under 5 years of age group still accounted for the most PMP-related deaths, with the number decreasing from 851,458 (95% UI: 211,026 to 1,363,810) in 1990 to 201,078 (95% UI:61,817 to 337,232). …”

Image2_Overexpression of vacuolar H+-pyrophosphatase from a recretohalophyte Reaumuria trigyna enhances vegetative growth and salt tolerance in transgenic Arabidopsis thaliana.tif by Ningning Li (566420)

“…Catalase enzyme activity, proline content, relative water content, and soluble sugar content were significantly increased in transgenic Arabidopsis under salt stresses, but the malondialdehyde content was dramatically decreased. …”

Table 1_The association between non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio and pulmonary function: evidence from NHANES 2007–2012.docx by Miaoyan Liu (11943570)

“…</p>Results<p>The results manifested a significant correlation between decreased FEV1 and FVC values and elevated NHHR, most notably within the highest quartile of NHHR (Q4), where the association was most pronounced. …”

Table 1_CD9 regulates proliferation, invasion, migration and radioresistance of esophageal squamous cell carcinoma by activating AKT/GSK3β signaling pathway.docx by Liubing Hou (10888140)

“…Background<p>Radioresistance poses a major therapeutic challenge in ESCC, significantly impacting patient prognosis. …”

DataSheet1_The long-term prognostic implications of free triiodothyronine to free thyroxine ratio in patients with obstructive sleep apnea and acute coronary syndrome.docx by Yun Zhou (308977)

“…The FT3/FT4 ratio between OSA and non-OSA patients was not significantly different. During 2.8 (1.4, 3.5) years follow up, the risk of MACCE increased with the decreasing FT3/FT4 tertiles in patients with OSA (tertile3 as reference, tertile2: hazard ratio (HR) 1.26, 95% CI: 0.85-1.86, P = 0.255; tertile1: 1.60, 95% CI 1.11-2.32; P = 0.013). …”

Data Sheet 1_Andrographolide suppresses chondrosarcoma cell migration and invasion by inhibiting the PI3K/Akt/mTOR signaling pathway and activating autophagy.pdf by Chun-Fei Wu (22315444)

“…WB results also revealed that Andro (5, 20, and 50 μM) reduced p62 expression, while Beclin-1 expression and the LC3A/B-II/LC3A/B-I ratio increased in SW1353 and Hs 819.T cells. …”

<b>Patterns</b><b> and drivers of </b><b>plant C:N:P stoichiometry</b><b> across a 3000 km aridity gradient</b> by Jianzhao Wu (19185964)

“…<p dir="ltr">Leaf element stoichiometry plays a crucial role in understanding nutrient dynamics and carbon cycling within ecosystems. …”

Table 1_The cerebral metabolic mechanism of group computer magnanimous therapy based on magnetic resonance spectroscopy: effects on improving magnanimous-enterprising levels of lun... by Qianyu Liu (7543004)

“…Significant increases in NAA/Cr levels were observed in the right amygdala, and significant decreases in mI/Cr levels were observed in the right cingulate gyrus in the GCMTG. …”

Table1_The interaction between selenium and other elements in soil and rice roots shaped by straw and straw biochar regulated the enrichment of selenium in rice grain.docx by Qinlei Rong (3815335)

“…The results showed that the incorporation of straw and straw biochar into the fields increased the content of soil-soluble Se (SOL-Se) but significantly decreased the content of iron-manganese oxide-bound Se (FMO-Se) and organic matter-bound Se (OM-Se). …”

Table 1_Efficacy and safety of tocilizumab in managing cytokine release syndrome after CD19 CAR-T therapy for relapsed or refractory B-cell acute lymphoblastic leukemia.docx by Qianyi Zhou (6196383)

“…</p>Results<p>Of these, 17 patients received tocilizumab, resulting in a significant reduction in the duration of grade 3 CRS compared to those who did not receive the drug. …”