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significantly increased » significant increase (Expand Search)
increased decrease » increased release (Expand Search), increased crash (Expand Search)
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18801
Table 3_Clinical features and prognosis of NMOSD patients with positive autoimmune antibodies.docx
Published 2025“…The primary outcomes included relapse rates, Expanded Disability Status Scale (EDSS) scores, and survival outcomes.</p>Results<p>(1) Anti-CTD Abs (+): higher proportion of female patients, increased relapse frequency; decreased red blood cell (RBC) count and aspartate aminotransferase (AST) levels. (2) ATAbs (+): greater incidence of acute brainstem syndrome (ABS); reduced peripheral leukocyte, neutrophil, and lymphocyte counts; elevated serum urea levels. (3) Double (+): marked female predominance, higher incidence of ABS, decreased RBC count, hemoglobin (Hb) levels, and cerebrospinal fluid (CSF) chloride concentration; elevated serum urea. (4) AQP4-IgG association: AQP4-IgG-positive patients were more frequently female, with higher prevalence of anti-CTD Abs positivity but lower prevalence of ATAbs positivity. (5) Prognostic analysis: both double-positive and single-antibody-positive groups showed higher disability (EDSS ≥4.0/≥6.0) compared with antibody-negative patients, although no significant differences were observed between the two single-antibody subgroups. (6) Multivariate analysis identified combined antibody positivity (OR = 16.292), baseline EDSS score (OR = 3.179), and age at onset (OR = 1.052) as independent predictors of poor clinical outcomes.…”
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18802
Comparison of 3D culture systems on mesenchymal stem cell longevity, regenerative potential, and secretome production
Published 2025“…LIF, OCT4, IGF1) were significantly higher in Bio-Block ASCs. …”
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18803
Image 2_Modulation of fenestrated vasculature in the median eminence and area postrema in response to neurotoxin exposure and its impairment in aging.tif
Published 2025“…In this study, we show that fenestrated capillaries in the median eminence (ME) and area postrema (AP)—two distinct circumventricular organs critical for metabolic control—undergo differential remodeling when exposed to circulating monosodium glutamate (MSG), a BBB-impermeable neurotoxin. Upon MSG exposure, fenestrated capillaries and vascular permeability were decreased in the ME but increased in the AP, and these changes were closely associated with the expression of angiogenic factors pleiotrophin (Ptn) and vascular endothelial growth factor A (Vegfa). …”
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18804
Table 2_Deletion of the GntR8 transcriptional regulator impairs Brucella abortus intracellular survival and virulence by modulating stress response genes.docx
Published 2025“…The results demonstrate that deletion of gntR8 markedly impairs intracellular survival of B. abortus in RAW264.7 cells and significantly reduces virulence in a mouse infection model. …”
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18805
Supplementary Material for: From childhood to adolescence: Long-term trends in severe obesity in German youth (2002–2023)
Published 2025“…Children between 12-16 years of age showed a continuous increase, especially boys (boys12-16: OR5: 1.3, girls12-16: OR5: 1.1, p<0.001). …”
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18806
“Engineering Rifampicin-Encapsulated Inhalable Microparticles for Precision Tuberculosis Therapy: In Vivo Distribution and Therapeutic Evaluation”
Published 2025“…The TB-infected mice, which showed the lung tissue bacterial load was reduced to 3.2 log colony forming unit (CFU) and the levels of TNF-α were decreased while IL-10 levels were increased. With this kind of accelerated stability testing it was ascertained that the type of formulation had a shelf-life of 24 months.…”
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18807
Supplemental Material for Dhiman et al., 2025
Published 2025“…Beyond reduced amylose content, <em>wxe</em> exhibited increased kernel hardness, elevated protein content, reduced endosperm-to-germ ratio, and decreased kernel weight compared to the wild-type. …”
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18808
Figure 4 from Impact of Glucocorticoids on Immune Checkpoint Inhibitor Efficacy and Circulating Biomarkers in Non–Small Cell Lung Cancer Patients
Published 2025“…<p>Continued use of corticosteroids during anti–PD-L1 therapy correlates with decreased survival in a preclinical model. …”
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18809
Statistical data.
Published 2025“…The results show that: (1) Habitat quality shows significant gradient characteristics, and the overall decreases from southeast to northwest. …”
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18810
Sensitivity of land types to threat factors.
Published 2025“…The results show that: (1) Habitat quality shows significant gradient characteristics, and the overall decreases from southeast to northwest. …”
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18811
Data Sheet 5_Global, regional, and national burden of IHD attributable to PM pollution aged 70 and above: an age-period-cohort modeling and frontiers analysis study.csv
Published 2025“…</p>Results<p>From 1990 to 2021, global age-standardized DALY rates for IHD attributable to PM pollution decreased by −1.51% annually, but absolute DALYs increased due to population aging and growth. …”
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18812
Data Sheet 4_Global, regional, and national burden of IHD attributable to PM pollution aged 70 and above: an age-period-cohort modeling and frontiers analysis study.csv
Published 2025“…</p>Results<p>From 1990 to 2021, global age-standardized DALY rates for IHD attributable to PM pollution decreased by −1.51% annually, but absolute DALYs increased due to population aging and growth. …”
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18813
Data Sheet 2_Global, regional, and national burden of IHD attributable to PM pollution aged 70 and above: an age-period-cohort modeling and frontiers analysis study.csv
Published 2025“…</p>Results<p>From 1990 to 2021, global age-standardized DALY rates for IHD attributable to PM pollution decreased by −1.51% annually, but absolute DALYs increased due to population aging and growth. …”
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18814
Data Sheet 3_Global, regional, and national burden of IHD attributable to PM pollution aged 70 and above: an age-period-cohort modeling and frontiers analysis study.csv
Published 2025“…</p>Results<p>From 1990 to 2021, global age-standardized DALY rates for IHD attributable to PM pollution decreased by −1.51% annually, but absolute DALYs increased due to population aging and growth. …”
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18815
Data Sheet 7_Global, regional, and national burden of IHD attributable to PM pollution aged 70 and above: an age-period-cohort modeling and frontiers analysis study.csv
Published 2025“…</p>Results<p>From 1990 to 2021, global age-standardized DALY rates for IHD attributable to PM pollution decreased by −1.51% annually, but absolute DALYs increased due to population aging and growth. …”
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18816
Data Sheet 6_Global, regional, and national burden of IHD attributable to PM pollution aged 70 and above: an age-period-cohort modeling and frontiers analysis study.csv
Published 2025“…</p>Results<p>From 1990 to 2021, global age-standardized DALY rates for IHD attributable to PM pollution decreased by −1.51% annually, but absolute DALYs increased due to population aging and growth. …”
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18817
Image 3_Cellular interactions and Ion channel signatures in atrial fibrillation remodeling: insights from single-cell analysis and machine learning.tif
Published 2025“…In the AF group, the proportions of EF, APF, and LBCs were increased, whereas the proportion of EC was decreased; by contrast, the SR group displayed a higher proportion of EC. …”
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18818
Table 3_Cellular interactions and Ion channel signatures in atrial fibrillation remodeling: insights from single-cell analysis and machine learning.xlsx
Published 2025“…In the AF group, the proportions of EF, APF, and LBCs were increased, whereas the proportion of EC was decreased; by contrast, the SR group displayed a higher proportion of EC. …”
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18819
Table 8_Cellular interactions and Ion channel signatures in atrial fibrillation remodeling: insights from single-cell analysis and machine learning.xlsx
Published 2025“…In the AF group, the proportions of EF, APF, and LBCs were increased, whereas the proportion of EC was decreased; by contrast, the SR group displayed a higher proportion of EC. …”
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18820
Table 2_Cellular interactions and Ion channel signatures in atrial fibrillation remodeling: insights from single-cell analysis and machine learning.xlsx
Published 2025“…In the AF group, the proportions of EF, APF, and LBCs were increased, whereas the proportion of EC was decreased; by contrast, the SR group displayed a higher proportion of EC. …”