يعرض 1 - 20 نتائج من 295 نتيجة بحث عن '(( significant ((large decrease) OR (largest decrease)) ) OR ( significant alterations _ ))', وقت الاستعلام: 0.11s تنقيح النتائج
  1. 1

    Biomolecular changes and subsequent time-dependent recovery in hippocampal tissue after experimental mild traumatic brain injury حسب Sebnem Garip Ustaoglu (18460611)

    منشور في 2021
    "…Band area and intensity ratios, band frequency and bandwidth values of specific spectral bands showed that TBI causes significant structural and contextual global changes including decrease in carbonyl content, unsaturated lipid content, lipid acyl chain length, membrane lipid order, total protein content, lipid/protein ratio, besides increase in membrane fluidity with an altered protein secondary structure and metabolic activity in hippocampus 24 h after injury. …"
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    Significance of Avicennia Marina in the Arabian Gulf Environment: A Review حسب Kaiprath Puthiyapurayil Haseeba (21392966)

    منشور في 2025
    "…However, in the past two decades Gulf mangroves have been facing significant threats, including extensive coastal development, shoreline modification by establishing marinas and ports, and climate change-associated impacts such as sea-level rise and altered precipitation patterns, which pose significant risks to this fragile ecosystem. …"
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    Beyond genetics: Exploring the role of epigenetic alterations in breast cancer حسب Kirti S. Prabhu (4246144)

    منشور في 2024
    "…These include alterations in DNA methylation, histone modifications, and the expression of non-coding RNAs. …"
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    Nox2 Activity Is Required in Obesity-Mediated Alteration of Bone Remodeling حسب Md Mizanur Rahman (14603354)

    منشور في 2018
    "…The bone levels of proinflammatory cytokines and proosteoclastogenic factors were also significantly elevated in WT-HFD mice as compared to KO-HFD mice. …"
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    A clustering metaheuristic for large orienteering problems حسب Almiqdad Elzein (13141038)

    منشور في 2022
    "…The metaheuristic aims to dramatically improve the computation time of a given Orienteering Problem algorithm without a significant decrease in the solution quality of that algorithm, especially for large Orienteering Problems. …"
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    Accelerated epigenetic aging and DNA methylation alterations in Berardinelli–Seip congenital lipodystrophy حسب Abeer Qannan (14779192)

    منشور في 2023
    "…We conclude that in line with the observed progeroid features, CGL2 patients exhibit significant epigenetic age acceleration and DNA methylation alterations that might affect pathways/genes of potential relevance to the disease.…"
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    Nanoparticle enrichment mass-spectrometry proteomics identifies protein-altering variants for precise pQTL mapping حسب Karsten Suhre (67967)

    منشور في 2024
    "…We identify 184 protein-altering variants in 137 genes that are significantly associated with their corresponding variant peptides, confirming target specificity of co-associated affinity binders, identifying putatively causal cis-encoded proteins and providing experimental evidence for their presence in blood, including proteins that may be inaccessible to affinity-based proteomics.…"
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    Serum metabolic signatures for Alzheimer’s Disease reveal alterations in amino acid composition: a validation study حسب Jonas Ellegaard Nielsen (21633062)

    منشور في 2024
    "…Pathway analysis of significantly altered metabolites in the validation set revealed that they are involved in branched-chain amino acids (BCAAs) and energy metabolism (glycolysis and gluconeogenesis). …"
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    Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion حسب Khoury, Nathalie

    منشور في 2014
    "…Our data suggest that kefir is able to inhibit the proliferation and induce apoptosis in HT‑29 and Caco‑2 CRC cells, yet it does not exhibit a significant effect on the motility and invasion of these cells in vitro.…"
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    Intravenous administration of gold nanoparticles in rats exhibit alterations in sphingomyelins, bile acids, sphingolipids, and cholesterol esters levels حسب Haya Al-Sulaiti (5449256)

    منشور في 2024
    "…Furthermore, treatment with AuNPs caused significant alterations in cholesterol ester levels, essential for lipid storage and transport, indicating disruptions in these mechanisms. …"
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    Transcriptional alterations of protein coding and noncoding RNAs in triple negative breast cancer in response to DNA methyltransferases inhibition حسب Ramesh Elango (7542068)

    منشور في 2021
    "…Concordantly, DNMT inhibition led to significant inhibition of TNBC cell proliferation, G2-M cell cycle arrest and induction of cell death. …"
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    Biomolecular alterations in acute traumatic brain injury (TBI) using Fourier transform infrared (FTIR) imaging spectroscopy حسب Fazle Rakib (5768069)

    منشور في 2021
    "…Understating the biochemical alterations associated with acute TBI is critical for brain plasticity and recovery. …"
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    A GRASP Approach for Solving Large-Scale Electric Bus Scheduling Problems حسب Raka Jovanovic (17947838)

    منشور في 2021
    "…The results of the conducted computational experiments indicate that an increase in infrastructure investment through high speed chargers can significantly decrease the size of the necessary fleets. …"
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    Dextran Sodium Sulfate-Induced Impairment of Protein Trafficking and Alterations in Membrane Composition in Intestinal Caco-2 Cell Line حسب Toutounji, Mohamad

    منشور في 2020
    "…DSS treatment significantly reduced the transepithelial electric resistance (TEER) and increased the epithelial permeability of Caco-2 cells, without affecting their viability. …"
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