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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
largest decrease » larger decrease (Expand Search), marked decrease (Expand Search)
large increases » marked increases (Expand Search), age increased (Expand Search)
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19561
Presentation 1_Bmi1 deficiency exacerbates hyperoxia-induced acute lung injury in mice.pptx
Published 2025“…</p>Results<p>Mice lacking Bmi1 versus WT exposed to hyperoxia exhibited hallmarks of human acute lung injury (ALI) such as increased lung permeability, alveolar edema, hemorrhage, interstitial thickening, and infiltration of immune cells; and alterations in lung mechanics, including increased elastance and decreased lung compliance.</p>Discussion<p>Bmi1<sup>−/−</sup> mice exhibit increased mitochondrial damage, increased oxidative stress, and significant changes in protein markers related to mitophagy compared to WT mice. …”
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19562
Data_Sheet_15_Global burden of multiple sclerosis and its attributable risk factors, 1990–2019.PDF
Published 2024“…</p>Conclusion<p>Although the global age-standardized DALY rate of MS decreased between 1990 and 2019, MS continues to account for a considerable number of DALYs and prevalent cases. …”
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19563
Supplementary file 1_Temporal interaction information and laser evoked responses: preliminary results in fibromyalgia patients with small fibers pathology.docx
Published 2025“…</p>Significance<p>These findings highlight the potential of TII in elucidating the complex interplay between peripheral nerve integrity and central sensitization in FM and other chronic pain disorders.…”
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19564
Image 1_Global burden of endometriosis from 1990 to 2021 and projections to 2050: a comprehensive analysis based on the global burden of disease study 2021.tif
Published 2025“…The age-standardized incidence rate (ASIR) experienced a decline of 1.07% from 1990 to 2021, while the age-standardized prevalence rate (ASPR) decreased by 0.95%. The incidence of EMT peaked among women aged 20–24 years, whereas mortality rates increased with advancing age. …”
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19565
Supplementary file 4_Global burden of pulmonary sarcoidosis from 1990 to 2021: a comprehensive analysis based on the GBD 2021 study.xlsx
Published 2025“…Nationally, the burden of the disease in 2021 is particularly significant in countries such as Mauritius and Italy. …”
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19566
Table 1_Molecular and epigenetic responses to crowding stress in rainbow trout (Oncorhynchus mykiss) skeletal muscle.xlsx
Published 2025“…Background<p>Chronic stress is a critical challenge in fish aquaculture, adversely affecting growth, health, and overall productivity. Among the most significant chronic stressors in intensive farming is crowding, which triggers the release of cortisol, the primary stress hormone in fish. …”
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19567
Table 4_Comparative analysis of actinorhizal nodule and associated soil microorganism diversity and structure in three Alnus species.xlsx
Published 2025“…</p>Results<p>The results showed that the microbial community α-diversity decreased significantly from the associated soil to the root nodule, and the microbial diversity in the root nodule of A. sibirica was not affected by the habitats. …”
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19568
Image 8_Salt tolerance characterization and genome-wide association study of Gossypium barbadense accessions reveal salinity-adaptive variations.jpeg
Published 2025“…VIGS of GbXTH27 exacerbated salt-induced wilting phenotypes and significantly decreased antioxidant enzyme activities.…”
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19569
Supplementary file 1_Clinical features of benign paroxysmal positional vertigo in the elderly.docx
Published 2025“…The elderly group had significantly higher median scores in the DHI impact than the middle-aged group (24 vs. 16, p = 0.008). …”
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19570
Table7_Dynamics of flavonoid metabolites in coconut water based on metabolomics perspective.xlsx
Published 2024“…The total flavonoid content in both types of coconut water exhibited a decreasing trend with developmental progression, but the total flavonoid content in CK was significantly higher than that in W5. …”
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19571
Data Sheet 1_Robotic hormonal and autonomic modulation for type 2 diabetes: ileal interposition and hepatic sympathectomy.pdf
Published 2025“…The first patient showed significant weight loss and reduced insulin requirements after 12 months. …”
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19572
Image 3_Multi-omics study on the effect of moderate-intensity exercise on protein lactylation in mouse muscle tissue.tif
Published 2025“…The lactylation levels of Mtatp8, Atp5mg, and Atp5po proteins in the exercise group were significantly decreased, while their protein levels were significantly increased. …”
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19573
Table 1_Multi-omics study on the effect of moderate-intensity exercise on protein lactylation in mouse muscle tissue.xlsx
Published 2025“…The lactylation levels of Mtatp8, Atp5mg, and Atp5po proteins in the exercise group were significantly decreased, while their protein levels were significantly increased. …”
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19574
Table 7_Pachymic acid alleviates metabolic dysfunction-associated steatotic liver disease by inhibiting ferroptosis through PPARα.xlsx
Published 2025“…</p>Results<p>HFD induced biochemical abnormalities and liver injury, which were significantly reversed by Pac, as evidenced by decreased plasma levels of AST (Aspartate aminotransferase), ALT (Alanine aminotransferase), TG (Triglyceride), and TC (Total cholesterol), and reduced hepatic TG and TC levels. …”
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19575
Table_1_Fermentation and Storage Characteristics of “Fuji” Apple Juice Using Lactobacillus acidophilus, Lactobacillus casei and Lactobacillus plantarum: Microbial Growth, Metabolis...
Published 2025“…After storage at 4°C for 30 days, the total amino acid content of fermented apple juice was significantly increased, although the viable cell counts and total phenolic content were decreased (p < 0.05). …”
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19576
Table 1_Identification of metabolic pathways modulated by GAM and NGAM in the inhibition of Staphylococcus aureus biofilm formation.xlsx
Published 2025“…The results indicated that 2–8% of GAM significantly inhibited S. aureus biofilm formation. …”
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19577
Image 2_sodA modulates in vitro and in vivo virulence of Yersinia enterocolitica.jpeg
Published 2025“…</p>Results<p>The ΔsodA mutant exhibited significantly reduced adhesion to and invasion of epithelial cells, impaired survival within macrophages, and decreased colonization in murine ileum and colon tissues. …”
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19578
Exploring the effects of COVID-19 on verbal memory function in schizophrenia: Multiple case study and brief literature review
Published 2024“…We calculated the Reliable Change Index to estimate the clinical significance of verbal memory performance changes, with annualized change rates in hippocampal volumes assessed against normative data. …”
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19579
Supplementary file 1_Wearable-derived heart rate variability and sleep monitoring as predictors of mood episodes in bipolar disorder: a case report.jpg
Published 2025“…The findings revealed that reductions in nocturnal RMSSD preceded the onset of depressive symptoms, while decreases in time spent in bed were significantly associated with the exacerbation of manic symptoms. …”
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19580
Environmental changes and human activities influence the spatial patterns of plant diversity in Eastern Eurasian Steppe
Published 2024“…The Hulun Buir Steppe exhibits a natural environmental gradient with decreasing precipitation and temperature from east to west. …”