Understanding the Role of GLUT2 in Dysglycemia Associated with Fanconi–Bickel Syndrome by Sanaa Sharari (12561952)

“…Our findings suggest that <i>SLC2A2</i> mutations cause dysglycemia in FBS either by a direct effect on GLUT2 expression and/or activity or, indirectly, by the dysregulated expression of miRNAs implicated in glucose homeostasis.…”

Identification of Genes Associated with Familial Focal Segmental Glomerulosclerosis Through Transcriptomics and In Silico Analysis, Including RPL27, TUBB6, and PFDN5 by Mahmoud, Anfal

“…Three genes (TUBB6, RPL27, and PFDN5) showed significant differential expression (p < 0.01) when comparing FSGS and MCD with healthy controls. …”
Get full text

Effects of habitat complexity on the abundance, species richness and size of darkling beetles (Tenebrionidae) in artificial vegetation by Bartholomew, Aaron

“…Increasing complexity appeared to lead to decreasing beetle widths. 9 beetle species were relatively rare in, or absent from, the higher complexity treatments, including 5 of the 6 largest species. 2 rare, small beetle species were only found in higher complexity treatments. …”
Get full text

Synergistic Effect of Epigenetic Inhibitors Decitabine and Suberoylanilide Hydroxamic Acid on Colorectal Cancer In vitro by Najem, Sonia A.

“…Background: Colorectal Cancer (CRC) is a common cause of oncological deaths worldwide. Alterations of the epigenetic landscape constitute a well-documented hallmark of CRC phenotype. …”
Get full text
Get full text
Get full text
Get full text

The Cancer Spliceome: Reprograming of Alternative Splicing in Cancer by Ettaib El Marabti (23276158)

“…<p dir="ltr">Alternative splicing allows for the expression of multiple RNA and protein isoforms from one gene, making it a major contributor to transcriptome and proteome diversification in eukaryotes. …”

Deletion of <i>RFX6</i> impairs iPSC-derived islet organoid development and survival, with no impact on PDX1⁺/NKX6.1⁺ progenitors by Noura Aldous (15429873)

“…Upon differentiating iPSCs lacking RFX6 into pancreatic islets, a significant decrease in PDX1 expression at the PF stage was observed, although this did not affect PPs co-expressing PDX1 and NKX6.1. …”

Stemming cardiovascular diseases in Qatar by Nature Research (16552612)

“…“Both Qatari nationals and expatriates should adopt healthier lifestyles to reduce the prevalence of these risk factors,” says Christos. Diabetes was the largest preventable risk factor to decrease heart attacks and strokes.…”

Influenza prevalence and vaccine efficacy among diabetic patients in Qatar by Swapna, Thomas

“…Among the typed IVA-positive cases, 33.4% were H1N1, and 7.7% were H3N2. A significant decrease in influenza infections was reported in vaccinated DM patients (14.5%) when compared to non-vaccinated patients (18.9%) (p-value = 0.006). …”
Get full text
Get full text
Get full text

Targeting of lactate dehydrogenase C dysregulates the cell cycle and sensitizes breast cancer cells to DNA damage response targeted therapy by Adviti Naik (673163)

“…<div><p>The cancer testis antigen (CTA) lactate dehydrogenase C (LDHC) is a promising anticancer target with tumor‐specific expression and immunogenicity. Interrogation of breast cancer patient cohorts from The Cancer Genome Atlas (TCGA) and Molecular Taxonomy of Breast Cancer International Consortium (METABRIC) indicate that upregulation of LDHC expression correlates with unfavorable prognosis. …”

Why do some countries produce more capital intensive output than others? by Toukan, Amjad

“…Based on my model I offer an explanation for the variation in physical capital intensity across countries where the model predictions show that a lower quality of governance in a country results in a decrease in the output of capital-intensive goods and an increase in the output of labor-intensive goods. …”
Get full text
Get full text
Get full text
Get full text

Influenza prevalence and vaccine efficacy among diabetic patients in Qatar by Swapna Thomas (17337925)

“…Among the typed IVA-positive cases, 33.4% were H1N1, and 7.7% were H3N2. A significant decrease in influenza infections was reported in vaccinated DM patients (14.5%) when compared to non-vaccinated patients (18.9%) (p-value = 0.006). …”

Shear Behavior of One-Way Reinforced Concrete Hollow Slabs Voided with PET Void Formers by Hasan, Haider H.

Get full text

Functional Characterization of Novel <i>MC4R </i>Variants Identified in Two Unrelated Patients with Morbid Obesity in Qatar by Idris Mohammed (751020)

“…In vitro analysis of the functional impact of these variants showed a significant reduction in cell surface receptor expression and impaired extracellular ligand binding activity, leading to reduced cAMP production. …”

Microbiome profiling of rotavirus infected children suffering from acute gastroenteritis by Muhammad U. Sohail (9522515)

“…Microbial dysbiosis caused by RV infection may significantly influence disease prognosis and the development of other chronic diseases. …”

Use of Ultrasound and Ionic Liquids to Enhance the Extractive Desulfurization of Oils by Zuraiqi, Karma

Get full text

Qatar’s immigrants at higher risk of diabetes by Nature Research (16552612)

“…The researchers stress, however, that their preliminary results should be confirmed in future studies involving larger numbers of participants. 1 “We would advise the Qatari government to screen all immigrants entering the country, as this would decrease the risk of unnecessary complications due to the late diagnosis of diabetes,” says lead author Dennis Mook-Nakamori. …”

Adjuvant Epigenetic Therapy of Decitabine and Suberoylanilide Hydroxamic Acid Exerts Anti-Neoplastic Effects in Acute Myeloid Leukemia Cells by Abou Najem, Sonia

“…The sequential combination of SAHA and DAC causes a profound antitumorigenic effect in AML cell lines by inducing the expression of tumor suppressor genes…”
Get full text
Get full text
Get full text
Get full text

Acute exposure to cigarette smoking followed by myocardial infarction aggravates renal damage in an In vivo mouse model by Kobeissy, Firas

“…Molecular analysis revealed that nephrin expression was significantly reduced in the S+MI group, whereas sodium-hydrogen exchanger-1 (NHE-1) was significantly increased, suggesting altered glomerular filtration and kidney functions. …”
Get full text
Get full text
Get full text
Get full text

Acquiring firms' stock returns by Raad, Elias

“…Results indicate that stockholders of mergers financed with stocks suffer significant losses. These losses are larger when management ownership is low and smaller in mergers that resulted in acquiring firm leverage decreases. …”
Get full text
Get full text
Get full text
Get full text

Preparation of Mesoporous/Microporous MnCo₂O₄ and Nanocubic MnCr₂O₄ Using a Single Step Solution Combustion Synthesis for Bifunction Oxy... by Anchu Ashok (14152020)

“…Chronoamperometric (CA) runs for 24 h shows excellent stability of MnCo₂O₄ without any significant decrease in the current or potential value in ORR and OER. …”