Image 1_Neuroimaging and molecular mechanism of action of Cang-ai volatile oil in the treatment of vascular cognitive impairment.tif حسب Bojun Chen (317487)

"…</p>Conclusion<p>This study demonstrates that CAVO therapy reduces inflammatory responses in brain regions of VCI rats, decreases apoptosis and necrosis, protects neurons in affected areas, and simultaneously enhances functional connectivity strength between brain regions in VCI rats, thereby exerting a cognitive-improving effect on VCI.…"

Supplementary file 3_Oxymatrine for inflammatory bowel disease in preclinical studies: a systematic review and meta-analysis.docx حسب Xuan Zhao (356028)

"…The data analysis results indicated that the disease activity index (DAI), histopathological score (HS), interleukin-6 (IL-6), interleukin-1β (IL-1β), tumor necrosis factor-α (TNF-α), nuclear factor-κB (NF-κB), and myeloperoxidase (MPO) activity in the IBD animal models significantly decreased following intervention with oxymatrine. …"

Analytic framework. حسب Muayad Albadrani (7495145)

"…</p><p>Results</p><p>Logistic regression analysis revealed a strong negative association where household income increases and indoor air pollution-related mortality significantly decreases. Specifically, Households in the highest income quartile showed a 22% reduction progressively in the odds of mortality risk compared to the lowest income quintile. …"

Data Sheet 2_KAE ameliorates LPS-mediated acute lung injury by inhibiting PANoptosis through the intracellular DNA-cGAS-STING axis.pdf حسب Yonghu Chen (2040136)

"…</p>Results<p>KAE significantly alleviated lipopolysaccharide-induced pulmonary injury by reducing inflammatory cell infiltration, alleviating pulmonary edema, enhancing antioxidant capacity, and decreasing levels of inflammatory cytokines in mouse lung tissues. …"

Data Sheet 2_Early boosting of p38 MAPK signaling pathway by lycorine hydrochloride potently inhibits PRRSV proliferation in primary and established cells.pdf حسب Lizhan Su (19936980)

"…Mechanistically, LH treatment induced a rapid up-regulation of p38 MAPK signaling pathway in both infected and uninfected cells, which enhanced the expressions of NLRP3 and Caspase-1 proteins, thereby promoting the conversion of pro-IL-1β to IL-1β, which led to decreased PRRSV replication. In summary, this study reveals that early boosting of p38 MAPK signaling pathway induced by LH treatment significantly suppresses PRRSV propagation, and LH has the potential to be used as a novel antiviral agent against PRRSV infections.…"

Descriptive statistics for the whole sample. حسب Muayad Albadrani (7495145)

"…</p><p>Results</p><p>Logistic regression analysis revealed a strong negative association where household income increases and indoor air pollution-related mortality significantly decreases. Specifically, Households in the highest income quartile showed a 22% reduction progressively in the odds of mortality risk compared to the lowest income quintile. …"

Data Sheet 1_Early boosting of p38 MAPK signaling pathway by lycorine hydrochloride potently inhibits PRRSV proliferation in primary and established cells.pdf حسب Lizhan Su (19936980)

"…Mechanistically, LH treatment induced a rapid up-regulation of p38 MAPK signaling pathway in both infected and uninfected cells, which enhanced the expressions of NLRP3 and Caspase-1 proteins, thereby promoting the conversion of pro-IL-1β to IL-1β, which led to decreased PRRSV replication. In summary, this study reveals that early boosting of p38 MAPK signaling pathway induced by LH treatment significantly suppresses PRRSV propagation, and LH has the potential to be used as a novel antiviral agent against PRRSV infections.…"

Data Sheet 1_KAE ameliorates LPS-mediated acute lung injury by inhibiting PANoptosis through the intracellular DNA-cGAS-STING axis.zip حسب Yonghu Chen (2040136)

"…</p>Results<p>KAE significantly alleviated lipopolysaccharide-induced pulmonary injury by reducing inflammatory cell infiltration, alleviating pulmonary edema, enhancing antioxidant capacity, and decreasing levels of inflammatory cytokines in mouse lung tissues. …"

Supplementary file 1_Oxymatrine for inflammatory bowel disease in preclinical studies: a systematic review and meta-analysis.docx حسب Xuan Zhao (356028)

"…The data analysis results indicated that the disease activity index (DAI), histopathological score (HS), interleukin-6 (IL-6), interleukin-1β (IL-1β), tumor necrosis factor-α (TNF-α), nuclear factor-κB (NF-κB), and myeloperoxidase (MPO) activity in the IBD animal models significantly decreased following intervention with oxymatrine. …"

<b>Astragalus polysaccharide and </b><b><i>Clostridium butyricum</i></b><b> synergistically inhibit bone loss in mice with humanized intestinal flora</b> حسب Hongtao Zhang (20774453)

"…., butyric acid) not only protect the intestinal mucosal barrier, but also regulate bone metabolism through the gut-bone axis and improve osteoporosis. …"

Table 1_Effects of biochar on phosphorus fraction, phosphatase activity, and phosphorus-solubilizing bacterial abundance: a phosphorus-depleted biochar design.docx حسب Hongyi Qin (5943515)

"…PDB did not significantly alter PSB diversity.</p>Conclusion<p>Phosphorus-depleted biochar reduces potentially available phosphorus fractions and mitigates phosphorus leaching, supporting aquatic ecosystem protection. …"

Image 2_Delineation of single-cell Altas provides new insights for development of coronary artery lesions in Kawasaki disease: bad and good signaling molecules.tif حسب Qiuping Lin (3091146)

"…In the monocytes of CAL patients, MCH-II is a significantly increased signal and RESISTIN is a significantly decreased signal compared to non-CAL counterpart.…"

Data Sheet 6_Congrong Shujing Granules ameliorates mitochondrial associated membranes to against MPP+-induced neurological damage in the cellular model of Parkinson’s disease.zip حسب Chutian Zhang (10732350)

"…The serum effectively mitigated damage within the MAMs region and reduced both the mitochondrial-Ca²⁺ fluorescence intensity and the expression of the IP₃R-VDAC-MCU complex in MPP⁺-induced neuronal cells. Additionally, it significantly decreased the levels of ROS, the decline in MMP, and apoptosis rates in these cells.…"

Table 4_Interactions between the intestinal microbiome and host genes in regulating vibriosis resistance in Cynoglossus semilaevis.xlsx حسب Weiwei Zheng (140828)

"…</p>Results<p>Obvious histopathological differences were observed between the resistant and susceptible groups in terms of inflammatory cells infiltration, and tissue dissociation of mucosal layer. 16S rRNA sequencing analysis indicated that Vibrio increased but Stenotrophomonas, Chryseobacterium, Delftia, and Salinivibrio decreased in the susceptible group. Compared to the control group, 1,986 differentially expressed genes (DEGs) were detected in the susceptible group, significantly more than the 310 DEGs found in the resistant group. …"

Data Sheet 9_Congrong Shujing Granules ameliorates mitochondrial associated membranes to against MPP+-induced neurological damage in the cellular model of Parkinson’s disease.zip حسب Chutian Zhang (10732350)

"…The serum effectively mitigated damage within the MAMs region and reduced both the mitochondrial-Ca²⁺ fluorescence intensity and the expression of the IP₃R-VDAC-MCU complex in MPP⁺-induced neuronal cells. Additionally, it significantly decreased the levels of ROS, the decline in MMP, and apoptosis rates in these cells.…"

Data Sheet 11_Congrong Shujing Granules ameliorates mitochondrial associated membranes to against MPP+-induced neurological damage in the cellular model of Parkinson’s disease.zip... حسب Chutian Zhang (10732350)

"…The serum effectively mitigated damage within the MAMs region and reduced both the mitochondrial-Ca²⁺ fluorescence intensity and the expression of the IP₃R-VDAC-MCU complex in MPP⁺-induced neuronal cells. Additionally, it significantly decreased the levels of ROS, the decline in MMP, and apoptosis rates in these cells.…"

Image 3_Delineation of single-cell Altas provides new insights for development of coronary artery lesions in Kawasaki disease: bad and good signaling molecules.tif حسب Qiuping Lin (3091146)

"…In the monocytes of CAL patients, MCH-II is a significantly increased signal and RESISTIN is a significantly decreased signal compared to non-CAL counterpart.…"

Data Sheet 3_Congrong Shujing Granules ameliorates mitochondrial associated membranes to against MPP+-induced neurological damage in the cellular model of Parkinson’s disease.pdf حسب Chutian Zhang (10732350)

"…The serum effectively mitigated damage within the MAMs region and reduced both the mitochondrial-Ca²⁺ fluorescence intensity and the expression of the IP₃R-VDAC-MCU complex in MPP⁺-induced neuronal cells. Additionally, it significantly decreased the levels of ROS, the decline in MMP, and apoptosis rates in these cells.…"

Data Sheet 8_Congrong Shujing Granules ameliorates mitochondrial associated membranes to against MPP+-induced neurological damage in the cellular model of Parkinson’s disease.zip حسب Chutian Zhang (10732350)

"…The serum effectively mitigated damage within the MAMs region and reduced both the mitochondrial-Ca²⁺ fluorescence intensity and the expression of the IP₃R-VDAC-MCU complex in MPP⁺-induced neuronal cells. Additionally, it significantly decreased the levels of ROS, the decline in MMP, and apoptosis rates in these cells.…"

Data Sheet 5_Congrong Shujing Granules ameliorates mitochondrial associated membranes to against MPP+-induced neurological damage in the cellular model of Parkinson’s disease.zip حسب Chutian Zhang (10732350)

"…The serum effectively mitigated damage within the MAMs region and reduced both the mitochondrial-Ca²⁺ fluorescence intensity and the expression of the IP₃R-VDAC-MCU complex in MPP⁺-induced neuronal cells. Additionally, it significantly decreased the levels of ROS, the decline in MMP, and apoptosis rates in these cells.…"