Data Sheet 1_Revealing fitness and virulence determinants of hypervirulent Klebsiella pneumoniae during infection in Galleria mellonella using a transposon library.pdf by Lisheng Xiao (15919517)

“…Going beyond the general knowledge that hypermucoviscosity (HMV) mediates high virulence, we observed that deficits in ptsI and GM2628 led to HMV while decreasing virulence. …”

Modulation of renal inflammation and tubular injury by calcitriol in patients with early diabetic kidney disease: a randomized controlled trial by Pringgodigdo Nugroho (15460802)

“…Although UACR decreased more in the calcitriol group, the difference was not statistically significant (<i>p</i> = 0.099). …”

Data Sheet 1_Targeting the leptin receptor promotes MDA-MB-231 cells’ metabolic reprogramming and malignancy: the role of extracellular vesicles derived from obese adipose tissue.d... by Carol Costa Encarnação (21412730)

“…Introduction<p>Leptin, a key adipokine secreted by adipose tissue (AT), has emerged as a critical mediator linking obesity and breast cancer, both of which are major global health concerns. …”

Table 1_The impact of IL-17A inhibitors on scalp and gut microbiota in psoriasis.docx by Wenxia Huang (12290795)

“…Regarding gut microbiota, significant differences in α-diversity richness were observed compared to healthy controls (P<0.05). …”

<b>Role of the Chaperone ClpB in</b><b> </b><b>Mycoplasma bovis</b><b> Virulence: Implications for </b><b>stress response, a</b><b>dhesion, </b><b>b</b><b>iofilm </b><b>d</b><b>eve... by Hui zhang (22187170)

“…Phenotypic characterization revealed that ClpB disruption attenuated key virulence attributes, including: impaired host cell adhesion capacity, significant reduction in biofilm formation (p<0.01), diminished induction of proinflammatory cytokines (IL-1β, IL-6, TNF-α) in infected BoMac cells, decreased extracellular nuclease activity. …”

Data Sheet 1_The impact of sublethal antimicrobial blue light on lipidomic changes of Escherichia coli and Salmonella Typhimurium.pdf by Jiaxin Wu (540397)

“…Notably, both strains demonstrated decreased unsaturated lipid intensity alongside increased malondialdehyde levels—a key oxidative stress marker. …”

Data Sheet 3_The impact of sublethal antimicrobial blue light on lipidomic changes of Escherichia coli and Salmonella Typhimurium.csv by Jiaxin Wu (540397)

“…Notably, both strains demonstrated decreased unsaturated lipid intensity alongside increased malondialdehyde levels—a key oxidative stress marker. …”

Data Sheet 2_The impact of sublethal antimicrobial blue light on lipidomic changes of Escherichia coli and Salmonella Typhimurium.csv by Jiaxin Wu (540397)

“…Notably, both strains demonstrated decreased unsaturated lipid intensity alongside increased malondialdehyde levels—a key oxidative stress marker. …”

Interactive effects of temperature and food ration on growth and mercury concentration in eastern brook trout by Ethan Rutledge (22284511)

“…Across a range of temperatures (16 – 24°C), Brook Trout growth rate decreased, and Hg concentration increased with temperature. …”

Data Sheet 1_Interstitial fluid transport in linea alba is involved in acupuncture-induced attenuation of ovarian hypofunction in aged rats.pdf by Yaoyao Zhu (3487937)

“…Background<p>Age-related ovarian dysfunction, characterized by declining follicular reserve and hormonal imbalance, poses a significant challenge in reproductive endocrinology, severely compromising fertility and quality of life. …”

Table 2_Multi-omics analysis and evidence of IL1R1 as a potential biomarker for diabetes-associated intervertebral disc degeneration.xlsx by Meng Yi (7853249)

“…IL1R1 emerged as the most significant risk factor. scRNA-seq revealed altered cellular composition in diabetic discs, notably increased proportion of granulocytes (predominantly neutrophils) and decreased proportion of nucleus pulposus (NP) cells. …”

Data Sheet 2_Multi-omics analysis and evidence of IL1R1 as a potential biomarker for diabetes-associated intervertebral disc degeneration.pdf by Meng Yi (7853249)

“…IL1R1 emerged as the most significant risk factor. scRNA-seq revealed altered cellular composition in diabetic discs, notably increased proportion of granulocytes (predominantly neutrophils) and decreased proportion of nucleus pulposus (NP) cells. …”

Data Sheet 1_Multi-omics analysis and evidence of IL1R1 as a potential biomarker for diabetes-associated intervertebral disc degeneration.pdf by Meng Yi (7853249)

“…IL1R1 emerged as the most significant risk factor. scRNA-seq revealed altered cellular composition in diabetic discs, notably increased proportion of granulocytes (predominantly neutrophils) and decreased proportion of nucleus pulposus (NP) cells. …”

Table 4_Multi-omics analysis and evidence of IL1R1 as a potential biomarker for diabetes-associated intervertebral disc degeneration.xlsx by Meng Yi (7853249)

“…IL1R1 emerged as the most significant risk factor. scRNA-seq revealed altered cellular composition in diabetic discs, notably increased proportion of granulocytes (predominantly neutrophils) and decreased proportion of nucleus pulposus (NP) cells. …”

Table 3_Multi-omics analysis and evidence of IL1R1 as a potential biomarker for diabetes-associated intervertebral disc degeneration.xlsx by Meng Yi (7853249)

“…IL1R1 emerged as the most significant risk factor. scRNA-seq revealed altered cellular composition in diabetic discs, notably increased proportion of granulocytes (predominantly neutrophils) and decreased proportion of nucleus pulposus (NP) cells. …”

Table 1_Multi-omics analysis and evidence of IL1R1 as a potential biomarker for diabetes-associated intervertebral disc degeneration.xlsx by Meng Yi (7853249)

“…IL1R1 emerged as the most significant risk factor. scRNA-seq revealed altered cellular composition in diabetic discs, notably increased proportion of granulocytes (predominantly neutrophils) and decreased proportion of nucleus pulposus (NP) cells. …”

Data Sheet 1_A dual inhibitor of TrxR1 and XIAP induces pyroptosis in melanoma.docx by Yuan Wang (14955)

“…Mechanistically, TRI-03 not only increases intracellular reactive oxygen species (ROS) levels by inhibiting TrxR1 activity but also decreases XIAP expression, leading to the activation of the caspase-9/caspase-3/GSDME axis and irreversible GSDME-mediated pyroptosis in melanoma cells. …”

Image 2_Load-bearing aerobic exercise prior to injury moderates systemic immunosuppression response to fracture.jpeg by Lia K. Strait (22229095)

“…Subjects that exercised before fracture had decreased post-fracture circulating immunosuppressive myeloid-derived suppressor cells and pain sensitivity, however there was no significant effect of prehabilitation on bone repair volume, defect bridging rate, or biomechanical properties. …”

Table 1_Load-bearing aerobic exercise prior to injury moderates systemic immunosuppression response to fracture.docx by Lia K. Strait (22229095)

“…Subjects that exercised before fracture had decreased post-fracture circulating immunosuppressive myeloid-derived suppressor cells and pain sensitivity, however there was no significant effect of prehabilitation on bone repair volume, defect bridging rate, or biomechanical properties. …”

Table 2_Load-bearing aerobic exercise prior to injury moderates systemic immunosuppression response to fracture.docx by Lia K. Strait (22229095)

“…Subjects that exercised before fracture had decreased post-fracture circulating immunosuppressive myeloid-derived suppressor cells and pain sensitivity, however there was no significant effect of prehabilitation on bone repair volume, defect bridging rate, or biomechanical properties. …”