Search alternatives:
significant challenges » significant challenge (Expand Search), significant changes (Expand Search)
challenges decrease » challenges case (Expand Search)
marked decrease » marked increase (Expand Search)
significant challenges » significant challenge (Expand Search), significant changes (Expand Search)
challenges decrease » challenges case (Expand Search)
marked decrease » marked increase (Expand Search)
-
1
-
2
Reliable high-PAP-1-loaded polymeric micelles for cancer therapy: preparation, characterization, and evaluation of anti-tumor efficacy
Published 2025“…Molecular simulations revealed that PAE’s tertiary amine protonation affected the self-assembly process, modifying hydrophobicity and resulting in larger, loosely packed particles. Furthermore, compared to free PAP-1 or PAP-1 combined with MDR inhibitors, PAP-1-loaded micelles significantly enhanced cytotoxicity and apoptosis induction in Jurkat and B16F10 cells, through mechanisms involving decreased mitochondrial membrane potential and elevated caspase-3 activity. …”
-
3