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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
largest decrease » larger decrease (Expand Search), marked decrease (Expand Search)
greater increase » year increase (Expand Search)
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20341
Table 1_The efficacy and safety of danuglipron and orforglipron in patients with type 2 diabetes and obesity: a systematic review and meta-analysis.docx
Published 2025“…Meta-analysis results demonstrated that danuglipron significantly decreased HbA1c (mean difference [MD]: −0.90; 95% CI: −1.06, −0.74), FPG (MD: −24.66; 95% CI: −30.45, −18.86) and weight (MD: −2.17; 95% CI: −3.10, −1.23) and improved FPI (MD: 2.94; 95% CI: 1.50, 4.38). …”
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20342
Table1_Prediction of the potentially suitable areas of Eucommia ulmoides Oliver in China under climate change based on optimized Biomod2 and MaxEnt models.doc
Published 2024“…<p>Eucommia ulmoides Oliver is a medicinal plant of significant economic importance. Its cortex has been employed for centuries to alleviate various conditions such as lumbar pain, knee pain, and osteoporosis. …”
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20343
Presentation 1_Global, regional, and national burden of cardiovascular disease attributable to high body mass index from 1990 to 2021 and projection to 2045.pptx
Published 2025“…Over the study period, the overall CVD burden attributable to HBMI decreased significantly, while the burden of atrial fibrillation and flutter increased. …”
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20344
Data Sheet 1_Synergistic effects of Candida albicans and Porphyromonas gingivalis biofilms on epithelial barrier function in a 3D aspiration pneumonia model.pdf
Published 2025“…Introduction<p>Polymicrobial infections involving Candida albicans and Porphyromonas gingivalis represent a significant challenge in maintaining epithelial barrier integrity. …”
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20345
Data Sheet 2_Changes in symptom pattern in Meniere's disease by duration: the need for comprehensive management.pdf
Published 2024“…The frequency and duration of vertigo attacks generally decreased over time, with attacks becoming shorter and less severe as the disease progressed. …”
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20346
Table 4_MicroRNAs regulate alveolar macrophage homeostasis and its function in lung fibrosis.xlsx
Published 2025“…Our recent study found that the loss of miRNAs in embryonic progenitors significantly decreased the number of TR-AMs in late-stage embryos, indicating that miRNAs are necessary for TR-AM development. …”
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20347
Table 1_Lumefantrine ameliorates DSS-induced colitis by targeting FLI-1 to suppress NF-κB signaling.docx
Published 2025“…Background<p>Current therapeutic options for inflammatory bowel disease (IBD) remain suboptimal due to limited efficacy, significant side effects, and high relapse rates, necessitating novel treatment strategies. …”
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20348
Image4_Integrating anoikis and ErbB signaling insights with machine learning and single-cell analysis for predicting prognosis and immune-targeted therapy outcomes in hepatocellula...
Published 2024“…Background<p>Hepatocellular carcinoma (HCC) poses a significant global health challenge due to its poor prognosis and limited therapeutic modalities. …”
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20349
Table1_Neutrophil extracellular traps as immunofibrotic mediators in RA-ILD; pilot evaluation of the nintedanib therapy.docx
Published 2024“…On the other hand, nintedanib treatment decreased NETs and sC5b-9 levels in RA-ILD patients.…”
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20350
Data Sheet 1_Multi level effects of Sanghuang Tongxie Formula on type 2 diabetes rats: a comprehensive analysis from intestinal bacteria to metabolome and transcriptome.xlsx
Published 2025“…</p>Results<p>SHTX treatment significantly altered the gut microbiota composition in T2DM rats, increasing the relative abundance of Bacteroidetes while decreasing that of Firmicutes, which was closely correlated with improved insulin sensitivity. …”
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20351
Table1_Myocardial infarction in rats was alleviated by MSCs derived from the maternal segment of the human umbilical cord.DOCX
Published 2024“…In rats with MI, maternal-MSCs significantly restored cardiac contractile function and reduced the infarct size. …”
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20352
Table 1_The effects of antioxidant supplementation on pain, oxidative stress markers, and clinical pregnancy rate in women with endometriosis: a systematic review and meta-analysis...
Published 2025“…The results showed that antioxidant supplementation significantly alleviated pelvic pain (continuous outcomes: SMD = −2.68; p < 0.00001; binary outcomes: RR = 9.31; p < 0.0001), dysmenorrhea (SMD = −1.77; p = 0.01; RR = 2.39; p = 0.03), and dyspareunia (SMD = −2.33; p = 0.01; RR = 5.40; p = 0.003), and significantly decreased peripheral blood malondialdehyde (MDA) levels (SMD = −7.58; p = 0.001). …”
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20353
Presentation 1_Unveiling the gut-heart potential connection: microbiota’s role in kawasaki disease and coronary artery lesions.zip
Published 2025“…Thirteen genera showed statistically significant changes, including Enterococcus, Bacteroides, Faecalibacterium, Agathobacter, Lachnospiraceae_NK4A136_group, Roseburia, Monoglobus, etc. …”
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20354
Table 2_Association of cardiorespiratory fitness with phenotypic age in younger population: a study based on the NHANES database.docx
Published 2025“…</p>Results<p>In the multivariable logistical regression analysis, maintenance of CRF was significantly and inversely associated with PAA, demonstrating a decreased risk of 42% in the high CRF group [OR (95% CI): 0.58 (0.36, 0.96), p = 0.033]. …”
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20355
Image11_Integrating anoikis and ErbB signaling insights with machine learning and single-cell analysis for predicting prognosis and immune-targeted therapy outcomes in hepatocellul...
Published 2024“…Background<p>Hepatocellular carcinoma (HCC) poses a significant global health challenge due to its poor prognosis and limited therapeutic modalities. …”
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20356
Data Sheet 1_Featured intestinal microbiota associated with hepatocellular carcinoma in various liver disease states.pdf
Published 2025“…In the CHB-HCC, CC-HCC, and DC-HCC groups, the abundance of Bacteroides, Prevotella, and Faecalibacterium gradually decreased, whereas Klebsiella, Haemophilus, and Streptococcus increased. …”
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20357
Green Fabrication of Biobased and Degradable Poly(lactic acid)/Poly(butylene succinate) Open-Cell Foams for Highly Efficient Oil–Water Separation with Ultrafast Degradation
Published 2024“…It is notable that different cell structures of varying sizes show significant differences in the adsorption capacity and rate. …”
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20358
Image4_Hypoxia-induced PD-L1 expression and modulation of muscle stem cell allograft rejection.JPEG
Published 2024“…In vivo, these preconditioned MuSCs led to decreased infiltration of CD4<sup>+</sup> and CD8<sup>+</sup> T cells in implanted limb muscles of mouse models. …”
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20359
Data Sheet 2_Rapid reshaping of the soil microbiome and metabolome during short-term flooding and draining in rice.docx
Published 2025“…The results revealed that S-PPO, S-POD, and S-CAT decreased with prolonged drainage time, whereas the soil redox potential (Eh-mV) and POD increased. …”
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20360
Data Sheet 1_The TFRC as a prognostic biomarker and potential therapeutic target in cervical cancer: a preliminary study.docx
Published 2025“…</p>Conclusions<p>TFRC exhibits significant diagnostic and prognostic value in cervical cancer.…”