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significant increased » significant increase (Expand Search), significant increases (Expand Search), significantly increased (Expand Search)
largest decrease » largest decreases (Expand Search), marked decrease (Expand Search)
larger decrease » marked decrease (Expand Search)
increased cgas » increased costs (Expand Search), increased odds (Expand Search), increased cell (Expand Search)
significant increased » significant increase (Expand Search), significant increases (Expand Search), significantly increased (Expand Search)
largest decrease » largest decreases (Expand Search), marked decrease (Expand Search)
larger decrease » marked decrease (Expand Search)
increased cgas » increased costs (Expand Search), increased odds (Expand Search), increased cell (Expand Search)
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HPV positive cells lacking cGAS display lower levels of γH2AX and cleaved caspases 3/7.
Published 2022Subjects: -
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Etoposide does not cause an early interferon response in primary or HPV positive keratinocytes.
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DNA damage induces cGAS expression in HPV positive cells while IFN has no effect.
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cGAS-STING canonical pathway is active and responsive in high risk HPV positive keratinocytes.
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