Showing 161 - 180 results of 12,186 for search '(( significant ((largest decrease) OR (larger decrease)) ) OR ( significant optimization process ))', query time: 2.04s Refine Results
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    Spatial information is significantly decreased in dCA1 and vCA1 in APP/PS1 mice. by Udaysankar Chockanathan (18510288)

    Published 2024
    “…The spatial information in dCA1 was significantly larger than circularly shuffled spike trains with similar mean firing rates for C57BL/6 mice (mean ± std: empirical = 0.132 ± 0.048, shuffled = 0.124 ± 0.035, p < 0.001, two-sided Wilcoxon rank-sum test, n<sub>empirical</sub> = 305 units from 5 recording sessions, n<sub>shuffled</sub> = 30500 simulated units from 5 recording sessions), but not for APP/PS1 mice (mean ± std: empirical = 0.128 ± 0.051, shuffled = 0.123 ± .047, p = 0.39, two-sided Wilcoxon rank-sum test, n<sub>empirical</sub> = 180 units from 4 recording sessions, n<sub>shuffled</sub> = 18000 simulated units from 4 recording sessions). …”
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    High-Throughput Experimentation Enabling Rapid Process Optimization of an RSV Drug Candidate by Xavier Jusseau (1486078)

    Published 2021
    “…Key to the identification of these optimal conditions was the use of high-throughput experimentation to greatly reduce the development time and realize significant process improvements in key steps such as the telescoped pyrazolopyrimidine core assembly and the borylation/Suzuki sequence.…”