Search alternatives:
significant optimization » significant limitation (Expand Search), significant application (Expand Search), significant association (Expand Search)
optimization process » optimization problems (Expand Search), optimization problem (Expand Search), optimization model (Expand Search)
largest decrease » largest decreases (Expand Search), marked decrease (Expand Search)
larger decrease » marked decrease (Expand Search)
significant optimization » significant limitation (Expand Search), significant application (Expand Search), significant association (Expand Search)
optimization process » optimization problems (Expand Search), optimization problem (Expand Search), optimization model (Expand Search)
largest decrease » largest decreases (Expand Search), marked decrease (Expand Search)
larger decrease » marked decrease (Expand Search)
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Spatial information is significantly decreased in dCA1 and vCA1 in APP/PS1 mice.
Published 2024“…The spatial information in dCA1 was significantly larger than circularly shuffled spike trains with similar mean firing rates for C57BL/6 mice (mean ± std: empirical = 0.132 ± 0.048, shuffled = 0.124 ± 0.035, p < 0.001, two-sided Wilcoxon rank-sum test, n<sub>empirical</sub> = 305 units from 5 recording sessions, n<sub>shuffled</sub> = 30500 simulated units from 5 recording sessions), but not for APP/PS1 mice (mean ± std: empirical = 0.128 ± 0.051, shuffled = 0.123 ± .047, p = 0.39, two-sided Wilcoxon rank-sum test, n<sub>empirical</sub> = 180 units from 4 recording sessions, n<sub>shuffled</sub> = 18000 simulated units from 4 recording sessions). …”
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High-Throughput Experimentation Enabling Rapid Process Optimization of an RSV Drug Candidate
Published 2021“…Key to the identification of these optimal conditions was the use of high-throughput experimentation to greatly reduce the development time and realize significant process improvements in key steps such as the telescoped pyrazolopyrimidine core assembly and the borylation/Suzuki sequence.…”