Supplementary Material for: Hypoxia reduces mouse urine output via HIF1α–mediated up–regulation of renal AQP1 حسب Qiao R. (10040630)

"…As transcription factors, HIFs are involved in the regulation of erythropoiesis, iron metabolism, angiogenesis, energy metabolism, and cell survival by promoting the transcriptional expression of hundreds of target genes. Roxadustat, a novel drug for the treatment of anemia associated with chronic kidney disease, acts by inhibiting the degradation of HIFs to increase their protein levels. …"

Data Sheet 1_Host and bacterial urine proteomics might predict treatment outcomes for immunotherapy in advanced non-small cell lung cancer patients.docx حسب David Dora (10278141)

"…RF was validated with a non-linear Bayesian ML model. Gene enrichment, and pathway analysis of host urine proteins were analyzed using the Reactome and Gene Ontology databases.…"

Table 3_Impact of short-term housing temperature alteration on metabolic parameters and adipose tissue in female mice.xlsx حسب Henry A. Paz (10263074)

"…Adipose tissue showed smaller adipocytes in iWAT and increased vascularity in BAT, though no persistent changes in thermogenic gene expression or glucose homeostasis were observed. …"

Table 2_Impact of short-term housing temperature alteration on metabolic parameters and adipose tissue in female mice.xlsx حسب Henry A. Paz (10263074)

"…Adipose tissue showed smaller adipocytes in iWAT and increased vascularity in BAT, though no persistent changes in thermogenic gene expression or glucose homeostasis were observed. …"

Table 1_Impact of short-term housing temperature alteration on metabolic parameters and adipose tissue in female mice.xlsx حسب Henry A. Paz (10263074)

"…Adipose tissue showed smaller adipocytes in iWAT and increased vascularity in BAT, though no persistent changes in thermogenic gene expression or glucose homeostasis were observed. …"

Supplementary Material for: Fibrillin-1 deficiency perturbs aortic cholinergic relaxation and adrenergic contraction in a mouse model of early onset progressively severe Marfan syn... حسب Cantalupo A. (20574239)

"…Results: Isometric force measurements of aortic rings from 16-day-old male Fbn1mgR/mgR mice revealed a significant reduction in acetylcholine (ACh)-induced relaxation and increased phenylephrine (PE)-promoted contractility, associated with abnormally low eNOSSer1177 phosphorylation, decreased NO production and augmented superoxide levels. …"

Image1_Oleic acid attenuates asthma pathogenesis via Th1/Th2 immune cell modulation, TLR3/4-NF-κB-related inflammation suppression, and intrinsic apoptotic pathway induction.tif حسب Soon-Young Lee (4721136)

"…The incidence is expected to increase as the average life expectancy increases, highlighting asthma as a significant health challenge in an aging society. …"

Understanding the Unknown: PTEN Intronic Non-Coding RNA in Breast Cancer حسب Muaz Asim Topal (22133146)

"…</li><li>This occurs instead of producing the normal PTEN protein, due to premature termination of the gene. </li><li>The absence of normal PTEN protein, which usually acts as a tumor suppressor, increases the risk of breast cancer. …"

Table 1_Variations in vitamin D status among Chinese children aged 1–6 years during the COVID-19 pandemic.xlsx حسب Yongfeng Qiao (3354326)

"…The average of 25(OH)D concentration were 38.2 ± 9.8 ng/ml, significantly varying by age and season. 25(OH)D concentrations decreased with age, from 42.3 ± 8.8 ng/ml at 1-year-olds to 37.4 ± 8.2 ng/ml at 2-year-olds, and further to 30.2 ± 8.1 ng/ml at 3 to 6-year-olds. …"

Effect of management activities on forest soil properties in the Rocky Mountains: II. Tree, stump, and downed woody debris data حسب Theresa B. Jain (10288169)

"…The specific purpose of the tree, stump, and downed woody debris study was to describe whether the growth of trees, and the amount of stumps or dead woody materials varied significantly on a site if it was dozer piled, prescribe burned, or in an unharvested area. …"

Data Sheet 1_Integrative assessment of the effects of ventilation systems on economic efficiency, milk production, and reproductive performance in dairy cows.docx حسب Arzu Peker (20880149)

"…However, their values were significantly lower under the most critical THI classes (p < 0.001). …"

Table 1_Association of cardiovascular health with reproductive lifespan and pregnancy loss: insights from NHANES 2005–2018.pdf حسب Yang Yan (222441)

"…Specifically, increased CVH levels were associated with increased age at menarche (β=0.14, 95% CI: 0.10, 0.18, P<0.001) and decreased age at menopause (β=−0.18, 95% CI: −0.33, −0.04, P=0.014). …"

Table 2_Association of cardiovascular health with reproductive lifespan and pregnancy loss: insights from NHANES 2005–2018.docx حسب Yang Yan (222441)

"…Specifically, increased CVH levels were associated with increased age at menarche (β=0.14, 95% CI: 0.10, 0.18, P<0.001) and decreased age at menopause (β=−0.18, 95% CI: −0.33, −0.04, P=0.014). …"

Data Sheet 1_Spatial visualization provides insight into immune modulation by an L-DBF vaccine formulation against Shigella.pdf حسب Ti Lu (405747)

"…Here, we investigate how a two-dose regimen (one prime and one booster) of L-DBF, formulated in an oil-in-water emulsion called ME, modulates immune responses in the lung using a spatial transcriptomics approach. Our findings show significant changes in the lung immune landscape following the vaccination, including increased expression of B cell markers, antigen presentation genes, and T cell-associated markers. …"

Table 1_Association of brain-derived neurotrophic factor in blood and cerebrospinal fluid with Parkinson’s disease and non-motor symptoms of Parkinson’s disease: a systematic revie... حسب Zhenzhen Zhao (782550)

"…A significant association was found between decreased serum BDNF concentrations and cognitive impairment in PD (SMD = −1.035; 95% CI [−1.340, −0.730]; P < 0.001). …"

Table 1_Salivary gland transcriptomic analysis and immunophenotyping in the IL-14α transgenic mouse model of Sjögren's disease.xlsx حسب Lucas T. Woods (11163549)

"…Results demonstrated significantly increased sialadenitis in IL-14αTG compared to C57BL/6 mice that correlated with an increased proportion of marginal zone B cells infiltrating the submandibular gland. …"

Table 2_Salivary gland transcriptomic analysis and immunophenotyping in the IL-14α transgenic mouse model of Sjögren's disease.xlsx حسب Lucas T. Woods (11163549)

"…Results demonstrated significantly increased sialadenitis in IL-14αTG compared to C57BL/6 mice that correlated with an increased proportion of marginal zone B cells infiltrating the submandibular gland. …"

Data Sheet 1_Salivary gland transcriptomic analysis and immunophenotyping in the IL-14α transgenic mouse model of Sjögren's disease.docx حسب Lucas T. Woods (11163549)

"…Results demonstrated significantly increased sialadenitis in IL-14αTG compared to C57BL/6 mice that correlated with an increased proportion of marginal zone B cells infiltrating the submandibular gland. …"

Additional file 1 of MDM2-amplified esophageal adenocarcinomas exhibit an activated metabolic and immunosuppressive phenotype with multiple potential therapeutic targets حسب Karl Knipper (15016346)

"…Volcano plot of all detected proteins comparing the proteome of neoadjuvantly treated MDM2-amplified and non-amplified tumors. Grey: not significantly different expressed, blue: significantly decreased expression in neoadjuvantly treated MDM2-amplified tumors, red: significantly increased expression in neoadjuvantly treated MDM2-amplified tumors. …"

Image 1_Functional characterization of FvCAMTA1in salt stress response of Fraxinus velutina.tif حسب Liping Yan (441024)

"…The heterologous overexpression of FvCAMTA1 in Arabidopsis significantly enhanced salt tolerance, resulting in higher germination rates, improved root elongation, and increased fresh weight, whereas the camta5 mutant exhibited heightened sensitivity. …"