Table 2_Transcriptomic analysis reveals the key role of inflammatory and immune signaling in the anti-perimenopausal depression effects of Bushen Shugan Huayu decoction.pdf by Ziqin Feng (22318243)

“…Key differentially expressed genes were validated via RT-PCR (qPCR) to quantify mRNA expression levels.</p>Results<p>Following BSSGHY decoction treatment, patients showed a significant reduction in HAMD scores (p < 0.01), marked symptom relief (p < 0.05), and decreased inflammatory factor levels (p < 0.01). …”

Table 2_Clinical features and prognosis of NMOSD patients with positive autoimmune antibodies.docx by Yutao Liu (87989)

“…</p>Results<p>(1) Anti-CTD Abs (+): higher proportion of female patients, increased relapse frequency; decreased red blood cell (RBC) count and aspartate aminotransferase (AST) levels. (2) ATAbs (+): greater incidence of acute brainstem syndrome (ABS); reduced peripheral leukocyte, neutrophil, and lymphocyte counts; elevated serum urea levels. (3) Double (+): marked female predominance, higher incidence of ABS, decreased RBC count, hemoglobin (Hb) levels, and cerebrospinal fluid (CSF) chloride concentration; elevated serum urea. (4) AQP4-IgG association: AQP4-IgG-positive patients were more frequently female, with higher prevalence of anti-CTD Abs positivity but lower prevalence of ATAbs positivity. (5) Prognostic analysis: both double-positive and single-antibody-positive groups showed higher disability (EDSS ≥4.0/≥6.0) compared with antibody-negative patients, although no significant differences were observed between the two single-antibody subgroups. (6) Multivariate analysis identified combined antibody positivity (OR = 16.292), baseline EDSS score (OR = 3.179), and age at onset (OR = 1.052) as independent predictors of poor clinical outcomes.…”

Table 4_Clinical features and prognosis of NMOSD patients with positive autoimmune antibodies.docx by Yutao Liu (87989)

“…</p>Results<p>(1) Anti-CTD Abs (+): higher proportion of female patients, increased relapse frequency; decreased red blood cell (RBC) count and aspartate aminotransferase (AST) levels. (2) ATAbs (+): greater incidence of acute brainstem syndrome (ABS); reduced peripheral leukocyte, neutrophil, and lymphocyte counts; elevated serum urea levels. (3) Double (+): marked female predominance, higher incidence of ABS, decreased RBC count, hemoglobin (Hb) levels, and cerebrospinal fluid (CSF) chloride concentration; elevated serum urea. (4) AQP4-IgG association: AQP4-IgG-positive patients were more frequently female, with higher prevalence of anti-CTD Abs positivity but lower prevalence of ATAbs positivity. (5) Prognostic analysis: both double-positive and single-antibody-positive groups showed higher disability (EDSS ≥4.0/≥6.0) compared with antibody-negative patients, although no significant differences were observed between the two single-antibody subgroups. (6) Multivariate analysis identified combined antibody positivity (OR = 16.292), baseline EDSS score (OR = 3.179), and age at onset (OR = 1.052) as independent predictors of poor clinical outcomes.…”

Table 1_Clinical features and prognosis of NMOSD patients with positive autoimmune antibodies.docx by Yutao Liu (87989)

“…</p>Results<p>(1) Anti-CTD Abs (+): higher proportion of female patients, increased relapse frequency; decreased red blood cell (RBC) count and aspartate aminotransferase (AST) levels. (2) ATAbs (+): greater incidence of acute brainstem syndrome (ABS); reduced peripheral leukocyte, neutrophil, and lymphocyte counts; elevated serum urea levels. (3) Double (+): marked female predominance, higher incidence of ABS, decreased RBC count, hemoglobin (Hb) levels, and cerebrospinal fluid (CSF) chloride concentration; elevated serum urea. (4) AQP4-IgG association: AQP4-IgG-positive patients were more frequently female, with higher prevalence of anti-CTD Abs positivity but lower prevalence of ATAbs positivity. (5) Prognostic analysis: both double-positive and single-antibody-positive groups showed higher disability (EDSS ≥4.0/≥6.0) compared with antibody-negative patients, although no significant differences were observed between the two single-antibody subgroups. (6) Multivariate analysis identified combined antibody positivity (OR = 16.292), baseline EDSS score (OR = 3.179), and age at onset (OR = 1.052) as independent predictors of poor clinical outcomes.…”

Table 3_Clinical features and prognosis of NMOSD patients with positive autoimmune antibodies.docx by Yutao Liu (87989)

“…</p>Results<p>(1) Anti-CTD Abs (+): higher proportion of female patients, increased relapse frequency; decreased red blood cell (RBC) count and aspartate aminotransferase (AST) levels. (2) ATAbs (+): greater incidence of acute brainstem syndrome (ABS); reduced peripheral leukocyte, neutrophil, and lymphocyte counts; elevated serum urea levels. (3) Double (+): marked female predominance, higher incidence of ABS, decreased RBC count, hemoglobin (Hb) levels, and cerebrospinal fluid (CSF) chloride concentration; elevated serum urea. (4) AQP4-IgG association: AQP4-IgG-positive patients were more frequently female, with higher prevalence of anti-CTD Abs positivity but lower prevalence of ATAbs positivity. (5) Prognostic analysis: both double-positive and single-antibody-positive groups showed higher disability (EDSS ≥4.0/≥6.0) compared with antibody-negative patients, although no significant differences were observed between the two single-antibody subgroups. (6) Multivariate analysis identified combined antibody positivity (OR = 16.292), baseline EDSS score (OR = 3.179), and age at onset (OR = 1.052) as independent predictors of poor clinical outcomes.…”

Table 3_Transcriptomic analysis reveals the key role of inflammatory and immune signaling in the anti-perimenopausal depression effects of Bushen Shugan Huayu decoction.pdf by Ziqin Feng (22318243)

“…Key differentially expressed genes were validated via RT-PCR (qPCR) to quantify mRNA expression levels.</p>Results<p>Following BSSGHY decoction treatment, patients showed a significant reduction in HAMD scores (p < 0.01), marked symptom relief (p < 0.05), and decreased inflammatory factor levels (p < 0.01). …”

Table 1_Transcriptomic analysis reveals the key role of inflammatory and immune signaling in the anti-perimenopausal depression effects of Bushen Shugan Huayu decoction.docx by Ziqin Feng (22318243)

“…Key differentially expressed genes were validated via RT-PCR (qPCR) to quantify mRNA expression levels.</p>Results<p>Following BSSGHY decoction treatment, patients showed a significant reduction in HAMD scores (p < 0.01), marked symptom relief (p < 0.05), and decreased inflammatory factor levels (p < 0.01). …”

Table 5_Transcriptomic analysis reveals the key role of inflammatory and immune signaling in the anti-perimenopausal depression effects of Bushen Shugan Huayu decoction.pdf by Ziqin Feng (22318243)

“…Key differentially expressed genes were validated via RT-PCR (qPCR) to quantify mRNA expression levels.</p>Results<p>Following BSSGHY decoction treatment, patients showed a significant reduction in HAMD scores (p < 0.01), marked symptom relief (p < 0.05), and decreased inflammatory factor levels (p < 0.01). …”

Table 6_Transcriptomic analysis reveals the key role of inflammatory and immune signaling in the anti-perimenopausal depression effects of Bushen Shugan Huayu decoction.pdf by Ziqin Feng (22318243)

“…Key differentially expressed genes were validated via RT-PCR (qPCR) to quantify mRNA expression levels.</p>Results<p>Following BSSGHY decoction treatment, patients showed a significant reduction in HAMD scores (p < 0.01), marked symptom relief (p < 0.05), and decreased inflammatory factor levels (p < 0.01). …”

Table 1_Housed feeding improves rumen health by influencing the composition of the microbiota in Honghe cattle.docx by Runqi Fu (15267554)

“…For rumen microbiota, the HES group significantly decreased alpha diversity. The core rumen bacterial communities were Bacteroidata, Firmicutes and Proteobacteria. …”

Table 1_Understanding the biochemical impact of leukoreduction on canine pRBC storage: a focus on reactive oxygen species and storage lesions.docx by Sun Woo Shin (22183162)

“…Notably, intraerythrocytic ROS levels increased in both groups (p < 0.05), driven by hemoglobin autoxidation (p < 0.05), though they decreased in later storage stages due to hemolysis and membrane vesiculation. …”

Table 2_Understanding the biochemical impact of leukoreduction on canine pRBC storage: a focus on reactive oxygen species and storage lesions.xlsx by Sun Woo Shin (22183162)

“…Notably, intraerythrocytic ROS levels increased in both groups (p < 0.05), driven by hemoglobin autoxidation (p < 0.05), though they decreased in later storage stages due to hemolysis and membrane vesiculation. …”

Data Sheet 1_A dual inhibitor of TrxR1 and XIAP induces pyroptosis in melanoma.docx by Yuan Wang (14955)

“…Mechanistically, TRI-03 not only increases intracellular reactive oxygen species (ROS) levels by inhibiting TrxR1 activity but also decreases XIAP expression, leading to the activation of the caspase-9/caspase-3/GSDME axis and irreversible GSDME-mediated pyroptosis in melanoma cells. …”

Data Sheet 1_Iron improves the antiviral activity of NK cells.docx by Simone Schimmer (85325)

“…Interestingly, although iron supplementation decreased the NK cell’s cytokine production, it significantly improved NK cell degranulation and the expression of cytotoxicity-associated proteins. …”

Cascara Pulp: A Novel Ingredient for Healthy Kombucha by Using Honey and Brown Sugar by Wanlapa Lorliam (12523628)

“…The alcohol concentration in cascara kombucha with 15% brown sugar was comparable to that with the same levels of honey. Increasing the amounts of brown sugar or honey significantly increased the total phenolic compounds but decreased the antioxidant capacity of cascara kombucha. …”

Deep reinforcement learning agents trained using a curriculum solve navigation tasks with delayed rewards. by William L. Tong (22238845)

“…The curriculum is shown in red. Note the significant forgetting shown by the student trained using INC approach compared to ADP. …”

Supplementary file 1_Potential interactions between traditional Chinese medicine and osimertinib: a Case Report.docx by Min Zhang (111999)

“…After adjusting the TCM prescription, the patient’s osimertinib C_trough was stable within the range of 145 and 228 ng/mL without significant adverse reactions and carcinoembryonic antigen levels stabilized. …”

Data Sheet 2_The effect of training intervention based on health belief model on self-care behaviors of women with gestational diabetes mellitus.pdf by Fatemeh Mohammadkhah (14157844)

“…Also, the comparison of averages of blood sugar levels after the intervention in the two groups indicated that fasting blood sugar level, A1C hemoglobin, and blood sugar levels measured 2 h after the meal significantly decreased in the intervention group (p < 0.001). …”

Data Sheet 1_The effect of training intervention based on health belief model on self-care behaviors of women with gestational diabetes mellitus.pdf by Fatemeh Mohammadkhah (14157844)

“…Also, the comparison of averages of blood sugar levels after the intervention in the two groups indicated that fasting blood sugar level, A1C hemoglobin, and blood sugar levels measured 2 h after the meal significantly decreased in the intervention group (p < 0.001). …”

Data Sheet 2_Metabolomics reveals key biomarkers for ischemic stroke: a systematic review of emerging evidence.pdf by Lu Ding (475637)

“…Metabolite analysis revealed associations between decreased proline, isoleucine, valine, and alanine levels with IS. …”