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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
greatest decrease » treatment decreased (Expand Search), greater increase (Expand Search)
level decrease » levels decreased (Expand Search), level increased (Expand Search), teer decrease (Expand Search)
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16081
Data Sheet 2_LncRNA NRIR inhibits osteogenesis by promoting macrophage M1 polarization through RSAD2/NF-κB axis in peri-implantitis.docx
Published 2025“…However, our previous studies revealed significant upregulation of NRIR in peri-implantitis, suggesting its potential role in peri-implantitis. …”
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16082
Table_1_Effectiveness of sofosbuvir-based treatments for patients with hepatitis C virus genotype 6 infection: a real-world study from East China.DOC
Published 2024“…Significant improvements were observed in the levels of total bilirubin, ALT, AST, albumin, globulin, albumin/globulin ratio, gamma-glutamyl transferase, alkaline phosphatase, platelet, fibrosis-4 (FIB-4), and aspartate transaminase to platelet ratio index (APRI) between baseline and EOT (p < 0.05).…”
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16083
Table 1_Protocatechuic aldehyde ameliorates high glucose-induced podocyte injury by attenuating inflammation, oxidative stress, and apoptosis via suppression of endoplasmic reticul...
Published 2025“…PCA significantly reduced the secretion of inflammatory cytokines (TNF-α, IL-1β, IL-6), restored the activities of SOD and GSH-Px, decreased MDA content, and downregulated the expression of Cox-2, iNOS, Nox2, and Nox4 proteins, thereby suppressing HG-induced podocyte inflammation and oxidative stress. …”
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16084
Raw data for main and supplemental figures
Published 2025“…We found that deletion of <i>proQ</i> significantly enhanced cell adherence ability of EHEC and led to upregulation of the locus of enterocyte effacement (LEE) pathogenicity island. …”
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16085
Table1_Around the clock: unveiling giraffe rest-activity rhythms and social dynamics.docx
Published 2024“…The presence of a male giraffe during one intervention phase significantly altered diurnal activity patterns, increasing standing behaviors and decreasing feeding time. …”
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16086
FLEXI interactions with RNA-binding proteins.
Published 2024“…RNA-binding sites: I, within introns corresponding to FLEXIs; SS-I and SS-E, bimodally enriched across the 5’- and 3’ splice sites in unspliced pre-mRNAs with the midpoints in the intron or flanking exon (SS-I and SS-E, respectively; Figs <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1011416#pgen.1011416.g004" target="_blank">4A</a> and <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1011416#pgen.1011416.s011" target="_blank">S11</a>). mRNA levels, RBPs whose knockdown resulted in significant difference in mRNA levels (increased or decreased, DESeq2 |LFC|≥1, adjusted p≤0.05) from host gene of FLEXIs with a binding site for that RBP compared to those genes whose transcripts lacked a binding site for the same RBPs based on ENCODE RBP-knockdown datasets (p≤0.05 calculated by Fisher’s exact test; <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1011416#pgen.1011416.s013" target="_blank">S13 Fig</a>). …”
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16087
Expression of <i>SHH</i> in the FEZ after RCAS-virus infection to induce overexpression and knockdown of <i>PBX1</i> and <i>PBX3.</i>
Published 2025“…Statistical significance was determined at P-value < 0.05; *, P < 0.05; **, P < 0.01; ****, P < 0.0001; ns, not significant.…”
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16088
Table 1_Weissella confusa alleviates experimental colitis in mice by regulating inflammatory pathways and gut microbiota.xlsx
Published 2025“…</p>Results<p>Compared with DSS group, W. confusa Wc1982 significantly improved the disease phenotypes of colitis mice including decreased DAI and pathological score and reduced colon shortening, decreased colonic IL-17, IL-6, and TNF-α levels and serum lipopolysaccharide (p < 0.05), and downregulated the expression of key genes of IL-17 pathway (Lcn2, Mmp3, Mmp13, Ptgs2; p < 0.05). …”
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16089
Supplementary file 1_Weissella confusa alleviates experimental colitis in mice by regulating inflammatory pathways and gut microbiota.docx
Published 2025“…</p>Results<p>Compared with DSS group, W. confusa Wc1982 significantly improved the disease phenotypes of colitis mice including decreased DAI and pathological score and reduced colon shortening, decreased colonic IL-17, IL-6, and TNF-α levels and serum lipopolysaccharide (p < 0.05), and downregulated the expression of key genes of IL-17 pathway (Lcn2, Mmp3, Mmp13, Ptgs2; p < 0.05). …”
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16090
Susceptibility of RUNX1 promoter rs2071029 polymorphism to adjuvant chemotherapy-induced neutropenia in CRC
Published 2025“…Rs2071029T promoter activity was significantly higher than that of rs2071029C promoter (<i>p</i> = 0.014). …”
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16091
Data Sheet 1_Balancing conservation and community needs: challenges, threats, and socioeconomic disparities in Kakamega Forest, Kenya.docx
Published 2025“…Illegal logging emerged as the most significant threat to KFE, regardless of wealth category, followed by a lack of awareness of conservation efforts, with significant differences in perception across wealth categories. …”
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16092
Effect of Gasdermin-D inhibition on expression of phenotypic transition markers in CER treated VSMCs during Vascular Calcification.
Published 2025“…(B) Summarized bar graph showed DIS significantly decreased calcium deposition in CER treated P<sub>i</sub>-induced VSMCs. …”
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16093
Effect of NLRP3 inhibition on expression of phenotypic transition markers in CER treated VSMCs during Vascular Calcification.
Published 2025“…(B) Summarized bar graph showed MCC950 significantly decreased calcium deposition in CER treated P<sub>i</sub>-induced VSMCs. …”
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16094
Figure 5 from Functional Profiling of p53 and RB Cell Cycle Regulatory Proficiency Suggests Mechanism-Driven Molecular Stratification in Endometrial Carcinoma
Published 2025“…<p>Aurora kinase B inhibitor sensitive endometrial carcinoma cells show more rapidly decreasing percentages of mitotic cells than resistant models in the setting of nocodazole-induced microtubule instability. …”
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16095
Raw Data.
Published 2025“…COS supplementation significantly increased serum superoxide dismutase activity and jejunal mucosal glutathione peroxidase activity, and significantly decreased serum malondialdehyde level (<i><i>P</i></i> < 0.05). …”
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16096
Supplementary file 1_Analysis of microbial composition in different dry skin areas of Beijing women.docx
Published 2025“…Compared to the lower leg, the back of the hand showed a higher relative abundance of Cutibacterium (34.19% vs. 8.68%), whereas the lower leg was predominantly colonized by Streptococcus (17% vs. 13.76%). At the genus level, the relative abundance of Streptococcus was significantly increased in the dry skin group, whereas a decreasing trend was observed for Cutibacterium. …”
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16097
DataSheet1_Erlotinib regulates short-term memory, tau/Aβ pathology, and astrogliosis in mouse models of AD.doc
Published 2024“…Furthermore, erlotinib-treated 5xFAD mice exhibited significant downregulation of astrocyte activation, and treating PACs from 5xFAD mice with erlotinib markedly reduced cxcl10 (reactive astrocyte marker) and gbp2 (A1 astrocyte marker) mRNA levels and proinflammatory cytokine mRNA and protein levels. …”
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16098
Table 1_The knowledge paradox: an inverted U-shaped association between HIV knowledge and stigma among older men in Sichuan Province, Southwest China.docx
Published 2025“…Background<p>Older men (≥50 years) in China face elevated HIV infection risks, yet HIV stigma remains a significant barrier to prevention. Although HIV knowledge is frequently assumed to reduce stigma, the evidence is inconsistent. …”
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16099
Data Sheet 2_Effect of thyme-ivy syrup on antiviral immune response in patients with mild COVID-19: a prospective, open-label, randomized pilot study.docx
Published 2025“…On day 7, numerically greater decreases in the thyme-ivy syrup group were observed for some mediators, including IL-10 (−17.7 vs. − 6.0 pg/mL; effect size 0.53) and IL-6 levels (−4.9 vs. − 0.9 pg/mL; effect size 0.87). …”
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16100
Image 1_Regulation effect of seed priming on sowing rate of direct seeding of rice under salt stress.pdf
Published 2025“…Our results demonstrated that under T1–T3, the germination rate, α-amylase activity, and soluble sugar and protein contents were significantly increased after priming treatments. The contents of reactive oxygen species (i.e., O<sub>2</sub><sup>−</sup> and H<sub>2</sub>O<sub>2</sub>) and malondialdehyde (MDA) were decreased, while the activities of enzymatic antioxidants (i.e., superoxide dismutase, peroxidase, and catalase) and the K<sup>+</sup>/Na<sup>+</sup> ratio of rice were significantly increased after the above seed priming treatments. …”