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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
greatest decrease » treatment decreased (Expand Search), greater increase (Expand Search)
level decrease » levels decreased (Expand Search), level increased (Expand Search), teer decrease (Expand Search)
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19301
Data Sheet 2_Congrong Shujing Granules ameliorates mitochondrial associated membranes to against MPP+-induced neurological damage in the cellular model of Parkinson’s disease.pdf
Published 2025“…The serum effectively mitigated damage within the MAMs region and reduced both the mitochondrial-Ca<sup>2+</sup> fluorescence intensity and the expression of the IP<sub>3</sub>R-VDAC-MCU complex in MPP<sup>+</sup>-induced neuronal cells. Additionally, it significantly decreased the levels of ROS, the decline in MMP, and apoptosis rates in these cells.…”
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19302
Table 2_Qinggan Yipi capsule ameliorates hepatic fibrosis in rats by down-regulating the TGF-β1/Smad2/3 signaling pathway and improving gut microbiota imbalance.docx
Published 2025“…</p>Results<p>Histopathological analysis, serum biochemical tests, and ELISA measurements showed that QgYp effectively decreased the levels of ALT, AST, HA, LN, PCIII, and IV-C while improving collagen deposition and hepatocyte necrosis. …”
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19303
Data Sheet 12_Congrong Shujing Granules ameliorates mitochondrial associated membranes to against MPP+-induced neurological damage in the cellular model of Parkinson’s disease.zip...
Published 2025“…The serum effectively mitigated damage within the MAMs region and reduced both the mitochondrial-Ca<sup>2+</sup> fluorescence intensity and the expression of the IP<sub>3</sub>R-VDAC-MCU complex in MPP<sup>+</sup>-induced neuronal cells. Additionally, it significantly decreased the levels of ROS, the decline in MMP, and apoptosis rates in these cells.…”
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19304
Data Sheet 2_Qinggan Yipi capsule ameliorates hepatic fibrosis in rats by down-regulating the TGF-β1/Smad2/3 signaling pathway and improving gut microbiota imbalance.pdf
Published 2025“…</p>Results<p>Histopathological analysis, serum biochemical tests, and ELISA measurements showed that QgYp effectively decreased the levels of ALT, AST, HA, LN, PCIII, and IV-C while improving collagen deposition and hepatocyte necrosis. …”
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19305
Data Sheet 1_Congrong Shujing Granules ameliorates mitochondrial associated membranes to against MPP+-induced neurological damage in the cellular model of Parkinson’s disease.pdf
Published 2025“…The serum effectively mitigated damage within the MAMs region and reduced both the mitochondrial-Ca<sup>2+</sup> fluorescence intensity and the expression of the IP<sub>3</sub>R-VDAC-MCU complex in MPP<sup>+</sup>-induced neuronal cells. Additionally, it significantly decreased the levels of ROS, the decline in MMP, and apoptosis rates in these cells.…”
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19306
Data Sheet 1_Nonlinear responses of ecosystem carbon fluxes to precipitation change in a semiarid grassland.doc
Published 2025“…We found that both decreased and increased precipitation significantly altered the GEP (from –26% to 14%), but only decreased precipitation significantly reduced the ER and NEE (from 1% to 31%), relative to their values during natural precipitation. …”
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19307
Table S13 from Functional Mapping of Epigenomic Regulators Uncovers Coordinated Tumor Suppression by the HBO1 and MLL1 Complexes
Published 2025“…<p>Categories and percent frequency of significantly decreased chromatin accessibility regions</p>…”
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19308
Impacts of winter climate change on northern forest understory carbon dioxide exchange determined by reindeer grazing
Published 2025“…On the contrary, increased snow depth decreased C source strength inside the exclusion offsetting the difference between reindeer grazing treatments. …”
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19309
Image 1_COP1 drives renal cell carcinoma progression by targeting ACSL4 for ubiquitin-mediated degradation and inhibiting ferroptosis.tif
Published 2025“…Mechanistically, COP1 directly bound ACSL4 and promoted its K48-linked ubiquitination, reducing ACSL4 protein stability by 70% (p < 0.001) and suppressing ferroptosis, as evidenced by decreased lipid ROS levels (p < 0.01) and reversal of ferroptosis inhibition by ferrostatin-1. …”
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19310
Data Sheet 1_Modified ZhuJing pill protects retinal pigment epithelium against oxidative stress-induced epithelial–mesenchymal transition through Nrf2-mediated Akt/GSK3β pathway.do...
Published 2025“…Notably, the EMT-suppressing effect of mZJP was significantly attenuated upon Nrf2 silencing, as evidenced by enhanced cell migration, decreased epithelial marker expression (E-cadherin), increased mesenchymal marker expression (vimentin and α-SMA), suppression of the Nrf2 pathway, and activation of the Akt/GSK3β pathway.…”
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19311
Image 4_The immunomodulatory and antitumor properties of the bacterial metalloprotease Oligopeptidase A are mediated by TLR4/MyD88/TRIF and MAPK signaling pathways.tiff
Published 2025“…</p>Results<p>Heat-inactivated OpdA significantly reduced metastasis, dependent on tumor-specific CD4+ and CD8+ T cells and IFN-γ, both locally and systemically, with decreased IL-10 levels suggesting a proinflammatory environment. …”
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19312
Image 2_The immunomodulatory and antitumor properties of the bacterial metalloprotease Oligopeptidase A are mediated by TLR4/MyD88/TRIF and MAPK signaling pathways.tiff
Published 2025“…</p>Results<p>Heat-inactivated OpdA significantly reduced metastasis, dependent on tumor-specific CD4+ and CD8+ T cells and IFN-γ, both locally and systemically, with decreased IL-10 levels suggesting a proinflammatory environment. …”
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19313
Image 3_Single-cell and spatial transcriptomics reveal correlation between RNA methylation-related miRNA risk model and immune infiltration in hepatocellular carcinoma.tif
Published 2025“…The data integration of scRNA-seq and bulk RNA-seq showed the decreased TIDE score in the high-risk patients and the elevated levels of Macro-secreted phosphoprotein 1 (SPP1), MDSC-meiotic nuclear divisions 1 (MND1), γδ T cells, and Macro-complement C1q C chain (C1QC) predicted adverse prognosis. …”
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19314
Image 2_Single-cell and spatial transcriptomics reveal correlation between RNA methylation-related miRNA risk model and immune infiltration in hepatocellular carcinoma.tif
Published 2025“…The data integration of scRNA-seq and bulk RNA-seq showed the decreased TIDE score in the high-risk patients and the elevated levels of Macro-secreted phosphoprotein 1 (SPP1), MDSC-meiotic nuclear divisions 1 (MND1), γδ T cells, and Macro-complement C1q C chain (C1QC) predicted adverse prognosis. …”
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19315
Image 1_The immunomodulatory and antitumor properties of the bacterial metalloprotease Oligopeptidase A are mediated by TLR4/MyD88/TRIF and MAPK signaling pathways.tif
Published 2025“…</p>Results<p>Heat-inactivated OpdA significantly reduced metastasis, dependent on tumor-specific CD4+ and CD8+ T cells and IFN-γ, both locally and systemically, with decreased IL-10 levels suggesting a proinflammatory environment. …”
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19316
Image 1_Fraxin modulates lipid metabolism as well as gut flora to avert NAFLD.tif
Published 2025“…GO and KEGG analyses suggested that fraxin primarily treats NAFLD by modulating lipid metabolism and atherosclerosis-related signaling pathways. In vivo, fraxin significantly lowered liver index and visceral fat accumulation, reduced serum levels of “interleukin-6 (IL-6),” “aspartate aminotransferase,” “tumor necrosis factor-α (TNF-α)” and “alanine aminotransferase,” and decreased hepatic TG content. …”
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19317
Image 1_Single-cell and spatial transcriptomics reveal correlation between RNA methylation-related miRNA risk model and immune infiltration in hepatocellular carcinoma.tif
Published 2025“…The data integration of scRNA-seq and bulk RNA-seq showed the decreased TIDE score in the high-risk patients and the elevated levels of Macro-secreted phosphoprotein 1 (SPP1), MDSC-meiotic nuclear divisions 1 (MND1), γδ T cells, and Macro-complement C1q C chain (C1QC) predicted adverse prognosis. …”
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19318
Image 3_The immunomodulatory and antitumor properties of the bacterial metalloprotease Oligopeptidase A are mediated by TLR4/MyD88/TRIF and MAPK signaling pathways.tiff
Published 2025“…</p>Results<p>Heat-inactivated OpdA significantly reduced metastasis, dependent on tumor-specific CD4+ and CD8+ T cells and IFN-γ, both locally and systemically, with decreased IL-10 levels suggesting a proinflammatory environment. …”
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19319
Data Sheet 1_Therapeutic potential of Glycyrrhiza polysaccharides in pseudorabies virus infection: immune modulation, antioxidant activity, and gut microbiota restoration.pdf
Published 2025“…Antioxidant activities (SOD, CAT) were enhanced, and MDA levels were decreased. Histological analyses showed recovery from villus atrophy and goblet cell loss. …”
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19320
Table 2_Single-cell and spatial transcriptomics reveal correlation between RNA methylation-related miRNA risk model and immune infiltration in hepatocellular carcinoma.xlsx
Published 2025“…The data integration of scRNA-seq and bulk RNA-seq showed the decreased TIDE score in the high-risk patients and the elevated levels of Macro-secreted phosphoprotein 1 (SPP1), MDSC-meiotic nuclear divisions 1 (MND1), γδ T cells, and Macro-complement C1q C chain (C1QC) predicted adverse prognosis. …”