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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
level increased » levels increased (Expand Search), levels decreased (Expand Search), gene increased (Expand Search)
level decrease » levels decreased (Expand Search), teer decrease (Expand Search), level disease (Expand Search)
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21201
Supplementary Material for: The Effectiveness of a Hospital-Based Antimicrobial Stewardship Program: A Three-Year Observational Study
Published 2025“…Conclusion: AMSP implementation was associated with process improvements and favourable trends in resistance and SMR, but most changes were not statistically significant. Increased re-admissions, ICU transfers, and inconsistent compliance highlight the need for sustained interventions and patient-level risk adjustment.…”
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21202
Table 1_Genetic susceptibility to gestational diabetes and its mild modification by bisphenol A and thyroid-stimulating hormone: findings from a South Chinese pregnancy cohort.docx
Published 2025“…</p>Conclusion<p>The study highlights the associations between GDM and the missense variant of PPARGC1A rs8192678, further revealing that the genetic effect is modified slightly by urinary BPA and serum TSH levels. The modification displayed a quasi-U-shaped distribution in relation to BPA and decreased as TSH levels increased.…”
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21203
Presentation 1_Genetic susceptibility to gestational diabetes and its mild modification by bisphenol A and thyroid-stimulating hormone: findings from a South Chinese pregnancy coho...
Published 2025“…</p>Conclusion<p>The study highlights the associations between GDM and the missense variant of PPARGC1A rs8192678, further revealing that the genetic effect is modified slightly by urinary BPA and serum TSH levels. The modification displayed a quasi-U-shaped distribution in relation to BPA and decreased as TSH levels increased.…”
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21204
Image 1_Genetic susceptibility to gestational diabetes and its mild modification by bisphenol A and thyroid-stimulating hormone: findings from a South Chinese pregnancy cohort.pdf
Published 2025“…</p>Conclusion<p>The study highlights the associations between GDM and the missense variant of PPARGC1A rs8192678, further revealing that the genetic effect is modified slightly by urinary BPA and serum TSH levels. The modification displayed a quasi-U-shaped distribution in relation to BPA and decreased as TSH levels increased.…”
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21205
Data Sheet 1_Intratumoral microbiota composition in women’s cancers: a systematic review and meta-analysis.docx
Published 2025“…Compared to adjacent normal tissues, the Simpson index significantly decreased in breast cancer (SMD = -0.75, 95% CI: [-0.94, -0.55]) and endometrial cancer (SMD = -0.83, 95% CI: [-1.37, -0.28]). …”
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21206
Table 1_MiR-216a-3p inhibits the cytotoxicity of primary natural killer cells.xlsx
Published 2025“…Thus, we evaluated FOXO-1 expression upon mimicking miR-216a-3p in control NK cells that showed significant downregulation of FOXO-1 on both RNA and protein levels.…”
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21207
DataSheet1_Exploring the naturally acquired response to Pvs47 gametocyte antigen.docx
Published 2024“…In summary, our study unveils a significant prevalence of anti-Pvs47 antibodies in diverse Amazonian samples and the importance of IgM response for gametocytes depuration. …”
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21208
Data Sheet 1_Anti-HLA antibodies bound to monocytes altered antibody-mediated platelet phagocytosis and led to mild thrombocytopenia.pdf
Published 2025“…Furthermore, the administration of anti-MHC-I antibodies to mice led to a significant decrease in the platelet count within 24 h. …”
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21209
Chromosomal partitioning is maintained during intracellular UPEC coccobacilli divisions.
Published 2025“…<b>i</b>, FtsZ-mNeonGreen (green) rings do not constrict over unsegregated chromosomes (HupA-RFP, pseudo-coloured magenta) in extracellular rods. Statistical significance was determined by student <i>T</i> test, where **** stars indicate p values less than 0.0001., n.s. = not significant. …”
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21210
Image 1_Emapalumab for severe cytokine release syndrome in solid tumor CAR-T: a case report.tif
Published 2025“…The hemodynamic improvement was associated with a decrease in IFN-γ and CXCL10 levels but no other cytokines. …”
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21211
Table 1_High-concentrate diet supplemented with hydrolysable tannin improves the slaughter performance, intestinal antioxidant ability and barrier function of fattening lambs.docx
Published 2024“…Also, tannin supplementation significantly increased (p < 0.05) the level of jejunal and ileal total antioxidant capacity and reduced (p < 0.05) the jejunal malondialdehyde concentration in lambs. …”
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21212
Figure 1 from Combined Oxygen-Enhanced MRI and Perfusion Imaging Detect Hypoxia Modification from Banoxantrone and Atovaquone and Track Their Differential Mechanisms of Action
Published 2025“…<b>C</b> and <b>D,</b> Clonogenic survival assays showed that banoxantrone became increasingly cytotoxic with reduced oxygenation whereas the impact of atovaquone on survival was not affected by oxygen level. …”
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21213
Clinical and biochemical determinants of length of stay, readmission and recurrence in patients admitted with diabetic ketoacidosis
Published 2024“…<p>The increasing prevalence of diabetic ketoacidosis (DKA) related admissions poses a significant burden on the healthcare systems globally. …”
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21214
Supplementary file 1_MoodyTunes: a single cohort study of a music-based smartphone app for mental health and mood regulation in young people.pdf
Published 2025“…Pre- and post-intervention measures assessed mental health literacy, coping self-efficacy, depression, anxiety, and stress levels. Results demonstrated a significant increase in mental health literacy and decreases in anxiety and stress. …”
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21215
S1 Data -
Published 2024“…Using the entropy method, Dagum Gini coefficient and Logarithmic Mean Divisia Index (LMDI) decomposition methods, the study examines the spatial and temporal distribution characteristics, spatial differences and driving effects of provincial well-being levels from 2007 to 2020. The results of this study suggest that the level of well-being as a whole, as well as in the eastern, central and western regions increased significantly over the period, with an “east-to-west decreasing” distribution in China. …”
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21216
Data Sheet 1_Effects of sodium tanshinone IIA sulfonate injection on pro-inflammatory cytokines, adhesion molecules and chemokines in Chinese patients with atherosclerosis and athe...
Published 2025“…</p>Conclusion<p>The use of STS in patients with AS and ASCVD appeared to significantly decrease levels of pro-inflammatory cytokines, adhesion molecules, and chemokines.…”
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21217
Presentation_1_Src Inhibition Attenuates Neuroinflammation and Protects Dopaminergic Neurons in Parkinson’s Disease Models.PDF
Published 2025“…The results showed that inhibition of Src could significantly relieve microgliosis and decrease levels of inflammatory factors. …”
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21218
Data Sheet 1_A ROS-responsive, aptamer-targeted graphene oxide nanocomposite for site-specific glutathione release in cerebral ischemia-reperfusion injury.docx
Published 2025“…In vitro, GO@GSH-FA significantly restored viability in oxygen-glucose-deprived SH-SY5Y cells (from 31% up to near control levels), reduced inflammatory cytokines, and lowered intracellular ROS. …”
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21219
Data Sheet 1_Causal relationship between inflammatory bowel disease and sex: a Mendelian randomization study.pdf
Published 2025“…</p>Results<p>There was no causal relationship between sex hormones and IBD in women (P > 0.05), and there was a causal and positive correlation between SHBG and testosterone and IBD in men.The OR for SHBG was 1.22 (95% CI: 1.09-1.37, P = 0.0004), and for testosterone was 1.20 (95% CI: 1.04-1.39, P = 0.0145).IBD did not significantly interact with female sex hormones but resulted in a decrease in SHBG (OR = 1.02, 95% CI: 1.00-1.04, P = 0.0195) and testosterone (OR = 1.01, 95% CI: 1.00 -1.02, P = 0.0200) in men.…”
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21220
Calcium Changes Following a Neighboring Cell Death
Published 2025“…The experiment revealed a sharp intracellular calcium spike in astrocytes following adjacent cell death, followed by a sustained decrease below baseline levels. Suramin-treated cells showed significantly reduced amplitude and peak rise, indicating that ATP-mediated activation of P2 receptors contributes to calcium influx.…”