Image 13_Serum neuritin as a predictive biomarker of early neurological deterioration and poor prognosis after spontaneous intracerebral hemorrhage: a prospective cohort study.tif by Yanwen Xu (663813)

“…A multivariate logistic regression model was used to assess the independent relationships between serum neuritin levels, END, and poor prognosis.</p>Results<p>Serum neuritin levels were significantly increased at the time of patient admission, continued to rise on day 1, peaked on day 3, and then gradually diminished from day 5 until day 10. …”

Image 1_Quantitative analysis of targeted lipidomics in the hippocampus of APP/PS1 mice employing the UHPLC-MS/MS method.jpeg by Shiyu Xiao (8147688)

“…Furthermore, hexosylceramides (HexCers) and ceramides (Cers) in the AD model’s hippocampus, the prominent sphingolipids in the hippocampus of AD mice, existed as the two primary changed lipid metabolites. The levels of some TGs in GLs and CEs in STs showed a significant elevation (p < 0.05, VIP > 1). …”

Image 2_Quantitative analysis of targeted lipidomics in the hippocampus of APP/PS1 mice employing the UHPLC-MS/MS method.jpeg by Shiyu Xiao (8147688)

“…Furthermore, hexosylceramides (HexCers) and ceramides (Cers) in the AD model’s hippocampus, the prominent sphingolipids in the hippocampus of AD mice, existed as the two primary changed lipid metabolites. The levels of some TGs in GLs and CEs in STs showed a significant elevation (p < 0.05, VIP > 1). …”

Supplementary file 1_A brief mindfulness intervention improves electrophysiological markers of attention in meditation-naïve individuals: the moderating role of inattention symptom... by Xiaoqian Yu (726144)

“…However, the mindfulness group exhibited a significantly greater increase compared to the control group. …”

Image 1_Alpha 1-antitrypsin mitigates salt-sensitive hypertension in juvenile mice by reducing diacylglycerol concentrations and protein kinase C activity in kidney membranes.tif by Yunus E. Dogan (19859574)

“…</p>Conclusion<p>Taken together, this study demonstrates a new protective effect of hAAT in normalizing blood pressure after the development of saltinduced hypertension in juvenile mice in a mechanism involving a decrease in NKCC2 membrane expression, presumably due to decreased levels of DAGs in the plasma membrane and a subsequent decrease in PKC activity.…”

Table 1_Alpha 1-antitrypsin mitigates salt-sensitive hypertension in juvenile mice by reducing diacylglycerol concentrations and protein kinase C activity in kidney membranes.docx by Yunus E. Dogan (19859574)

“…</p>Conclusion<p>Taken together, this study demonstrates a new protective effect of hAAT in normalizing blood pressure after the development of saltinduced hypertension in juvenile mice in a mechanism involving a decrease in NKCC2 membrane expression, presumably due to decreased levels of DAGs in the plasma membrane and a subsequent decrease in PKC activity.…”

Table 1_Trend of electroconvulsive therapy use and its relationships with clinical characteristics from a large psychiatric center in China.doc by Wei Li (7081)

“…</p>Results<p>In all, 2,213 (10.0%) inpatients received ECT, with an average number of sessions of 10.3 ± 6.6. There were no significant differences between the ECT and non-ECT groups in terms of educational level, marital status, length of hospital stay, and blood pressure. …”

Supplementary file 1_Distance and orientation of hydrophones influence the received soundscape in shallow coral reefs.docx by Juan Carlos Azofeifa-Solano (10983207)

“…</p>Results<p>Hydrophones oriented horizontally toward the reef exhibited the expected decrease in sound levels with increasing distance. …”

Table 1_The effects of magnesium and vitamin D/E co-supplementation on inflammation markers and lipid metabolism of obese/overweight population: a systematic review and meta-analys... by Kai Deng (299054)

“…In contrast, the serum levels of interleukin-6 (IL-6) showed a non-significant decrease (MD: −0.09, 95%CI: −0.33, 0.15, p = 0.46), and did not significantly affect lipid metabolism according to levels of parameters such as serum triglyceride (MD = 1.84, 95% CI: −28.92, 32.60, p = 0.91), serum LDL-c (MD: −4.56, 95% CI: −14.19, 5.08, p = 0.35), and serum HDL-c (MD: 1.96, 95% CI: −3.07, 6.98, p = 0.45) in the co-supplementation of magnesium and Vitamin E.…”

Data Sheet 3_IFNβ drives ferroptosis through elevating TRIM22 and promotes the cytotoxicity of RSL3.pdf by Huiyue Dong (4808436)

“…</p>Results<p>Here, we found that IFNβ could promote intracellular Fe²⁺ and lipid peroxidation levels, and decrease GSH levels in tumor cells. RNA sequencing data revealed that IFNβ induced a transcriptomic disturbance in ferroptosis-related genes. …”

Data Sheet 1_IFNβ drives ferroptosis through elevating TRIM22 and promotes the cytotoxicity of RSL3.pdf by Huiyue Dong (4808436)

“…</p>Results<p>Here, we found that IFNβ could promote intracellular Fe²⁺ and lipid peroxidation levels, and decrease GSH levels in tumor cells. RNA sequencing data revealed that IFNβ induced a transcriptomic disturbance in ferroptosis-related genes. …”

Data Sheet 2_IFNβ drives ferroptosis through elevating TRIM22 and promotes the cytotoxicity of RSL3.pdf by Huiyue Dong (4808436)

“…</p>Results<p>Here, we found that IFNβ could promote intracellular Fe²⁺ and lipid peroxidation levels, and decrease GSH levels in tumor cells. RNA sequencing data revealed that IFNβ induced a transcriptomic disturbance in ferroptosis-related genes. …”

Table 1_Effects of the efficacy of the Yi Shen Tiao Gan formula on aromatase inhibitor associated musculoskeletal syndrome: a randomized controlled trial.xlsx by Yan Zhang (8098)

“…There was no significant difference in bone metabolism levels between the two groups (p > 0.05), but the decrease in β-CTX was slightly slower in the treatment group of the AI + OFS population compared to the control group. …”

Data Sheet 1_Impact of zero-markup consumable policy and national procurement of coronary stents on hospitalization expenses: an interrupted time series analysis.pdf by Shao-long Wu (1948273)

“…Background<p>After the successful reforms of drug pricing, China has implemented two significant reforms to reduce medical consumables expenses: the elimination of markup on prices (zero-markup policy) and the implementation of centralized procurement of high-value medical consumables (national procurement policy). …”

<b>Epigenetic signatures of treatment with intravenous furosemide plus hypertonic saline solution in decompensated heart failure patients: A Randomized Controlled Trial ( RCT)</b> by Antonino Tuttolomondo (3222708)

“…</p><p dir="ltr">Conclusions: Our findings revealed that in subjects with ADHF , treatment with i.v. furosemide plus HSS significantly decreased the serum levels of IL-6, sST2, hsTnT, galectin-3, and NT-proBNP and modulated some miRNA expression.…”

Table_1_Regional and social disparities in cessation behavior and motivation to quit among U.S. adult current smokers, Tobacco Use Supplement to the U.S. Census Bureau's Current Po... by Candon Johnson (11572623)

“…Notably, the Asian non-Hispanic group in the Northeast experienced a significant decrease in quit interest (–17.9%) but an increase in recent successful cessation (+369.2%).…”

DataSheet1_Bacillus amyloliquefaciens TL promotes gut health of broilers by the contribution of bacterial extracellular polysaccharides through its anti-inflammatory potential.docx by Shijie Li (759509)

“…-TL markedly enhanced chicken growth performance, concomitant with a significant decrease in the expression of genes encoding inflammatory cytokines (e.g., CCL4, CCR5, XCL1, IL-1β, IL-6, IL-8, LITAF, and LYZ) in jejunum and ileum tissues. …”

Data Sheet 1_Urinary microbiota changes among NMIBC patients during BCG therapy: comparing BCG responders and non-responders.docx by Toni Boban (20852165)

“…Patient inclusion criteria were male gender, no previous history of urothelial cancer, no other malignancies, no active infection, and no antibiotic usage for at least 20 days before the first BCG dose. We observed a significant decrease in biodiversity, measured by the Shannon Index, during the first week of therapy in 10 out of 12 patients (p=0.021). …”

Data_Sheet_1_Global burden of drug use disorders by region and country, 1990–2021.docx by Shuyan Zhang (426593)

“…Nationally, the United States of America reported the largest increase in age-standardized DALY rates and EAPC for ASIR (EAPC of 4.88, 1.05, respectively), while South Africa had the most significant decrease in EAPC (EAPC of −3.62, −1.52, respectively). …”

Table_2_Global burden of drug use disorders by region and country, 1990–2021.docx by Shuyan Zhang (426593)

“…Nationally, the United States of America reported the largest increase in age-standardized DALY rates and EAPC for ASIR (EAPC of 4.88, 1.05, respectively), while South Africa had the most significant decrease in EAPC (EAPC of −3.62, −1.52, respectively). …”