Table 1_Integrated metabolomics and gut microbiota analysis to explore the potential mechanism of levo-tetrahydropalmatine against ketamine addiction.xlsx by Yan Du (229593)

“…L-THP also enriched Firmicutes, Lactobacillus, Dubosiella, unclassified_Clostridia_UCG_014, and Ligilactobacillus while decreasing the levels of Bacteroidota, Campylobacterota, Patescibacteria, unclassified_Bacilli, UCG_005, Prevotella, and Romboutsia. …”

KEGG Enrichment Analysis. by Guolian Wu (21464168)

“…Immune cell infiltration analysis gusing the XCell algorithm showed increased levels of Monocytes, neutrophils, and other immune cells in KD, while B cells and T cells were decreased. …”

Figure 1. by Guolian Wu (21464168)

“…Immune cell infiltration analysis gusing the XCell algorithm showed increased levels of Monocytes, neutrophils, and other immune cells in KD, while B cells and T cells were decreased. …”

Gene Name to ID Conversion. by Guolian Wu (21464168)

“…Immune cell infiltration analysis gusing the XCell algorithm showed increased levels of Monocytes, neutrophils, and other immune cells in KD, while B cells and T cells were decreased. …”

Bar Chart. by Guolian Wu (21464168)

“…Immune cell infiltration analysis gusing the XCell algorithm showed increased levels of Monocytes, neutrophils, and other immune cells in KD, while B cells and T cells were decreased. …”

Filter Samples with p < 0.05. by Guolian Wu (21464168)

“…Immune cell infiltration analysis gusing the XCell algorithm showed increased levels of Monocytes, neutrophils, and other immune cells in KD, while B cells and T cells were decreased. …”

KEGG Diagram. by Guolian Wu (21464168)

“…Immune cell infiltration analysis gusing the XCell algorithm showed increased levels of Monocytes, neutrophils, and other immune cells in KD, while B cells and T cells were decreased. …”

Grouping and Sorting. by Guolian Wu (21464168)

“…Immune cell infiltration analysis gusing the XCell algorithm showed increased levels of Monocytes, neutrophils, and other immune cells in KD, while B cells and T cells were decreased. …”

Violin Plot. by Guolian Wu (21464168)

“…Immune cell infiltration analysis gusing the XCell algorithm showed increased levels of Monocytes, neutrophils, and other immune cells in KD, while B cells and T cells were decreased. …”

XCell Algorithm for Immune Cell Matrix. by Guolian Wu (21464168)

“…Immune cell infiltration analysis gusing the XCell algorithm showed increased levels of Monocytes, neutrophils, and other immune cells in KD, while B cells and T cells were decreased. …”

Data Sheet 1_Polyphenol-mediated microbiome modulation in STEMI patients: a pilot study.zip by Argul Issilbayeva (21398168)

“…</p>Conclusion<p>Our findings demonstrate that polyphenol supplementation maintains stable TMAO levels by restructuring gut microbiome composition in STEMI patients, evidenced by a more focused microbiome with a significant increase in beneficial butyrate-producing bacteria (Roseburia, Agathobaculum sp., Alistipes finegoldii, and Sellimonas) and a decreased Firmicutes/Bacteroidetes ratio, suggesting microbiome-mediated cardioprotective effects. …”

Data Sheet 1_Efficacy and safety of pseudolaric acid B against Echinococcus multilocularis in vitro and in a murine infection model.pdf by Zhuo-ma Dawa (20632718)

“…After PAB treatment, the levels of CD4⁺ T lymphocytes increased and the levels of CD8⁺ T lymphocytes decreased in the host tissue surrounding the metacestodes and the spleen. …”

Combating Chemoresistance in Breast Cancer: Exploring Tumor Microenvironment, Combination Therapies, and Drug Repurposing Strategies by Shazia Sofi (17764488)

“…Chemoresistance in cancer can arise from a variety of molecular mechanisms, including active drug expulsion (drug efflux), decreased drug uptake, enhanced DNA repair mechanisms, the ability of cancer cells to evade programmed cell death (apoptosis), the diversity in the population of cancer cells within a tumor (tumor heterogeneity), and significant alterations in the tumor microenvironment (TME), where interactions between cancer cells, cancer-associated fibroblasts, immune cells, and the extracellular matrix contribute to a supportive environment that allows tumors to survive treatment and escape therapy. …”

DataSheet3_Dysregulation of the 3β-hydroxysteroid dehydrogenase type 2 enzyme and steroid hormone biosynthesis in chronic kidney disease.xlsx by Yiyi Zuo (19945293)

“…</p>Results<p>Metabolic characteristics revealed significant shifts in CKD, with 61 metabolites increased and 65 metabolites decreased, highlighting the disruption in steroid hormone biosynthesis pathways influenced by HSD3B2. …”

Data Sheet 1_The TFRC as a prognostic biomarker and potential therapeutic target in cervical cancer: a preliminary study.docx by Jing Wang (6206297)

“…Increased TFRC expression was linked to decreased overall survival (OS) (p = 0.024), disease-specific survival (DSS) (p = 0.009), and progression-free interval (PFI) (p = 0.007) in CESC patients. …”

DataSheet2_Dysregulation of the 3β-hydroxysteroid dehydrogenase type 2 enzyme and steroid hormone biosynthesis in chronic kidney disease.xlsx by Yiyi Zuo (19945293)

“…</p>Results<p>Metabolic characteristics revealed significant shifts in CKD, with 61 metabolites increased and 65 metabolites decreased, highlighting the disruption in steroid hormone biosynthesis pathways influenced by HSD3B2. …”

DataSheet1_Dysregulation of the 3β-hydroxysteroid dehydrogenase type 2 enzyme and steroid hormone biosynthesis in chronic kidney disease.pdf by Yiyi Zuo (19945293)

“…</p>Results<p>Metabolic characteristics revealed significant shifts in CKD, with 61 metabolites increased and 65 metabolites decreased, highlighting the disruption in steroid hormone biosynthesis pathways influenced by HSD3B2. …”

Supplementary file 1_Succession characteristics and assembly process of soil microbiome at reclaimed farmlands in coal mining area.doc by Jianhua Li (36075)

“…Results showed that (1) Compared to R0, the R10 treatment resulted in significant increases in soil organic matter (SOM), total nitrogen (TN), available phosphorus (AP), and available potassium (AK) by 2.1-fold, 1.3-fold, 1.5-fold, and 0.4-fold, and also in activities of β-glucosidase (BG), N-acetyl-β-glucosaminidase (NAG), and leucine aminopeptidase (LAP), by 17-fold, 8.7-fold, and 1.8-fold, respectively (p < 0.05). (2) Rising bacterial diversity (Shannon, Chao1) over time, contrasting with fungal diversity that declined initially before recovering. (3) As the reclamation progressed, the network complexity was increased for both bacteria and fungi, improving stability. …”

Genetic interaction between <i>Zrf1</i> and RISC components regulates ISC proliferation during midgut damage. by Joshua Shing Shun Li (22505522)

“…<p><b>(A)</b> Western blot analysis of adult fly lysates showing protein levels of Vig and Vig2 in various genetic backgrounds. …”

Table 1_Mendelian randomization and bioinformatics unveil potential links between gut microbial genera and colorectal cancer.xlsx by Long Wu (655081)

“…Background<p>Colorectal cancer (CRC) poses a significant global health burden, with high incidence and mortality rates. …”