Supplementary file 1_Full-dose versus reduced-dose comparison of direct oral anticoagulants for extended treatment of venous thromboembolism: a systematic review and meta-analysis... by Renshu Zhang (22775495)

“…</p>Conclusion<p>Reduced-dose DOACs were associated with a significant decrease in the risk of major bleeding/CRNMB compared with full-dose DOACs, but were not associated with a significant increase in the risk of recurrent VTE. …”

Supplementary file 1_Phase angle as a predictor of prolonged length of hospital stay and adverse outcomes in elderly medical inpatients: a retrospective cohort study.docx by Jia Liu (41593)

“…Adverse event rates across the PhA tertiles (T1–T3) were 32.9%, 18.6%, and 5.6%, respectively, indicating a significant decrease in event incidence as PhA values increased. …”

Data Sheet 1_Global, regional, and national burden of acute glomerulonephritis in children and adolescents: 1990–2021 analysis and future projections.docx by Ming Liu (105953)

“…</p>Results<p>From 1990 to 2021, the global burden of AGN among children and adolescents remained significantly high. In 2021, there were approximately 170,584 new cases, representing a decrease compared to earlier years, with an age-standardized incidence rate (ASIR) of 6.47 per 100,000 (95% UI: 4.79–8.45). …”

Data Sheet 1_Deep crustal composition and Late Paleozoic geotectonic evolution in West Junggar, China.pdf by Shenglin Xu (12076840)

“…During the Early Permian-Early Triassic period (272–250 Ma), magmatic activity decreased significantly, where the southwestern region experienced high-temperature, low-pressure, crustal thinning extension. …”

Decadal changes in species composition of rare oak <i>Quercus chungii</i> forests with logging history by Wenbin Li (9244088)

“…A larger contribution from balanced abundance variations than abundance gradient to the temporal <i>β </i>diversity suggested that there was no significant consistent increase or decrease in species abundance during this decade. …”

Data Sheet 3_Immunometabolic alterations in type 2 diabetes mellitus revealed by single-cell RNA sequencing: insights into subtypes and therapeutic targets.csv by Huahua Li (6896339)

“…</p>Results<p>In patients with T2DM, a marked increase in monocytes and a decrease in CD4+ T cells were observed, indicating immune dysregulation. …”

Table 2_The impact of the herd health interventions in small ruminants in low input production systems in Ethiopia.docx by Mesfin Mekonnen Moliso (19920393)

“…Generally, the intervention impact analysis revealed that morbidity rate was significantly decreased (p = 0.009) in intervention years (6.31% in 2018 to 3.02% in 2021) and that herd health interventions provide an added value.…”

DataSheet2_Asparagus officinalis L. extract exhibits anti-proliferative and anti-invasive effects in endometrial cancer cells and a transgenic mouse model of endometrial cancer.pdf by Ziwei Fang (10115899)

“…Asparagus officinalis extract treatment for 4 weeks resulted in a significant reduction in tumor growth in Lkb1^fl/flp53^fl/fl mice under both obese and lean conditions, with a decrease in Ki-67 and vascular endothelial growth factor expression and an increase in Bip expression in endometrial tumors.…”

hsa-miR-144-3p and hsa-miR-4262 are exosomal biomarkers and function as tumor suppressors in HCMV positive brain tumor by Muhammad Shahbaz Haris (13918249)

“…Data analysis showed significant decreased levels of <i>hsa-miR-144-3p</i> (p < 0.0001) and <i>hsa-miR-4262</i> (p < 0.0001) in brain tumor patients compared to controls. …”

Image 1_Effects of dietary fiber on Chinese children with functional constipation and targeted modification of gut microbiota and related metabolites.pdf by Pei Xiao (466657)

“…At the genus level, the relative abundances of Lachnospiraceae_ND3007_group, Lactococcus, Prevotella, and Anaerofustis significantly increased, whereas Enterobacter, DTU089, and Sutterella showed significant decreases. …”

Supplementary Material for: Global, Regional, and National Burden of Neonatal Encephalopathy Due to Birth Asphyxia and Trauma, Its Attributable Risk Factors, 1990-2021: Results fro... by figshare admin karger (2628495)

“…Low SDI regions experienced a substantial 112.9% increase in NEBAT cases, while high-middle SDI regions witnessed a significant 34.8% decrease. Although mortality rates declined across all SDI regions, the low SDI region had the smallest decline. …”

Secondary and tertiary outcomes. by Maram Khaled (14642937)

“…Primary outcome is pain intensity with movement (elicited by asking the patient to move from supine to sitting position) using 0–10 Numerical Rating Scale (0 = no pain, 10 = worst possible pain).</p><p>Significance</p><p>The results of this study may result in improved pain control, maternal satisfaction and wound healing; decrease the use of perioperative opioids; potentially decrease the incidence of postpartum depression and persistent pain; and overall lead to better postoperative outcomes thereby decreasing healthcare costs.…”

CONSORT flow diagram. by Maram Khaled (14642937)

“…Primary outcome is pain intensity with movement (elicited by asking the patient to move from supine to sitting position) using 0–10 Numerical Rating Scale (0 = no pain, 10 = worst possible pain).</p><p>Significance</p><p>The results of this study may result in improved pain control, maternal satisfaction and wound healing; decrease the use of perioperative opioids; potentially decrease the incidence of postpartum depression and persistent pain; and overall lead to better postoperative outcomes thereby decreasing healthcare costs.…”

Treatment consequence and adverse events of cyclin-dependent kinase 4/6 inhibitors on patients with hormone receptor-positive, HER2-negative metastatic breast cancer: a systematic... by Hsiang-Ying Wu (22212274)

“…This meta-analysis found that HR(+)/HER2(−) metastatic breast cancer treated with CDK4/6 inhibitors plus endocrine therapy can significantly improve progression-free survival(PFS) (HR: 0.55; <i>p</i> < 0.001), overall survival (OS) (HR: 0.79; <i>p</i> < 0.001), objective response rate (RR = 1.50; <i>p</i> < 0.001), clinical benefit rate (RR = 1.18; <i>p</i> < 0.001) and decrease progressive disease rate (RR = 0.49; <i>p</i> < 0.001). …”

Data_ALL by Myriam Campos Aguilar (15856298)

“…<p dir="ltr">Metabolic syndrome (MetS) is a clinical condition characterized by multiple risk Q8 factors that significantly increase the likelihood of developing cardiovascular diseases and type 2 diabetes. …”

Table 1_A study of the adjunctive therapeutic effects of a 3-week bamboo forest therapy on chronic diseases in the elderly.docx by Jing He (58446)

“…Diabetic participants showed significant decreases in fasting and pre-bedtime blood glucose levels (p < 0.001), along with reduced blood glucose fluctuations post-meal. …”

Data_Sheet_1_Effects of COVID-19-targeted non-pharmaceutical interventions on pediatric hospital admissions in North Italian hospitals, 2017 to 2022: a quasi-experimental study int... by Giuseppe Maglietta (12992976)

“…Level change for Mental Disorders significantly decreased during school closure (HRR 0.50, 95%CI 0.30–0.82) but increased during mitigation measures by 28% (HRR 1.28, 95%CI 0.98–1.69).…”

Data_Sheet_1_Effects of COVID-19-targeted non-pharmaceutical interventions on pediatric hospital admissions in North Italian hospitals, 2017 to 2022: a quasi-experimental study int... by Giuseppe Maglietta (12992976)

“…Level change for Mental Disorders significantly decreased during school closure (HRR 0.50, 95%CI 0.30–0.82) but increased during mitigation measures by 28% (HRR 1.28, 95%CI 0.98–1.69).…”

Fig 8 - by Shima Bahramizadeh-Sajadi (20391247)

“…Within each ring category, the area significantly affects the outcomes (p < 0.043), except for the change in corneal thickness of the horizontal category (p > 0.197), and for the contact pressure of the vertical ring category (p > 0.164).…”

Recognizing the biological barriers and pathophysiological characteristics of the gastrointestinal tract for the design and application of nanotherapeutics by Shan Li (110392)

“…Therapeutics for GIT disease treatment face multiple biological barriers, which significantly decrease the efficacy of therapeutics. …”