Image_2_Prognostic value of the Naples Prognostic Score in adult chronic obstructive pulmonary disease: NHANES 2005–2018.TIFF by Yue Kang (427523)

“…A trend toward a decreasing prevalence of lung function indicators such as FEV1 [OR (95%CI), −339.70 (−456.53, −222.87)], FVC [OR (95%CI), −296.70 (−435.34, −158.06)], FEV1/FVC [OR (95%CI), −0.03 (−0.04, −0.02)], predicted FEV1 [OR (95%CI), −0.09 (−0.14, −0.04)], and predicted FVC [OR (95%CI), −0.08 (−0.15, −0.01)] was observed with increased NPS levels. …”

Data Sheet 1_Identification of potential biomarkers for lung adenocarcinoma: a study based on bioinformatics analysis combined with validation experiments.zip by Chuchu Zhang (2562154)

“…Meanwhile, TGFBR2 expression was decreased in LUAD group through immunohistochemistry. …”

Dynamic changes in mRNA stability. by Shiqi Luo (3829597)

“…<b>(D)</b> GO analysis showing the enriched biological processes for mRNAs with increased (left) or decreased (right) stability in 6 hours of LPS treatment. …”

Data Sheet 1_IDO1-AhR axis increases T regulatory cells in Plasmodium vivax malaria infection.pdf by Rafaella Oliveira dos Santos (21710366)

“…Introduction<p>Malaria remains a significant public health challenge in Brazil, where Plasmodium vivax (P. vivax) is the predominant species. …”

Data Sheet 2_LncRNA NRIR inhibits osteogenesis by promoting macrophage M1 polarization through RSAD2/NF-κB axis in peri-implantitis.docx by Renshengjie Zhao (22459771)

“…However, our previous studies revealed significant upregulation of NRIR in peri-implantitis, suggesting its potential role in peri-implantitis. …”

Table_1_Effectiveness of sofosbuvir-based treatments for patients with hepatitis C virus genotype 6 infection: a real-world study from East China.DOC by Fan-Rong Jiang (20325720)

“…Significant improvements were observed in the levels of total bilirubin, ALT, AST, albumin, globulin, albumin/globulin ratio, gamma-glutamyl transferase, alkaline phosphatase, platelet, fibrosis-4 (FIB-4), and aspartate transaminase to platelet ratio index (APRI) between baseline and EOT (p < 0.05).…”

Table 1_Protocatechuic aldehyde ameliorates high glucose-induced podocyte injury by attenuating inflammation, oxidative stress, and apoptosis via suppression of endoplasmic reticul... by Yishu Wang (845334)

“…PCA significantly reduced the secretion of inflammatory cytokines (TNF-α, IL-1β, IL-6), restored the activities of SOD and GSH-Px, decreased MDA content, and downregulated the expression of Cox-2, iNOS, Nox2, and Nox4 proteins, thereby suppressing HG-induced podocyte inflammation and oxidative stress. …”

Raw data for main and supplemental figures by Runhua Han (20455670)

“…We found that deletion of <i>proQ</i> significantly enhanced cell adherence ability of EHEC and led to upregulation of the locus of enterocyte effacement (LEE) pathogenicity island. …”

Table1_Around the clock: unveiling giraffe rest-activity rhythms and social dynamics.docx by Hanna Mebus (19961244)

“…The presence of a male giraffe during one intervention phase significantly altered diurnal activity patterns, increasing standing behaviors and decreasing feeding time. …”

FLEXI interactions with RNA-binding proteins. by Jun Yao (9646)

“…RNA-binding sites: I, within introns corresponding to FLEXIs; SS-I and SS-E, bimodally enriched across the 5’- and 3’ splice sites in unspliced pre-mRNAs with the midpoints in the intron or flanking exon (SS-I and SS-E, respectively; Figs <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1011416#pgen.1011416.g004" target="_blank">4A</a> and <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1011416#pgen.1011416.s011" target="_blank">S11</a>). mRNA levels, RBPs whose knockdown resulted in significant difference in mRNA levels (increased or decreased, DESeq2 |LFC|≥1, adjusted p≤0.05) from host gene of FLEXIs with a binding site for that RBP compared to those genes whose transcripts lacked a binding site for the same RBPs based on ENCODE RBP-knockdown datasets (p≤0.05 calculated by Fisher’s exact test; <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1011416#pgen.1011416.s013" target="_blank">S13 Fig</a>). …”

Expression of <i>SHH</i> in the FEZ after RCAS-virus infection to induce overexpression and knockdown of <i>PBX1</i> and <i>PBX3.</i> by Chan Hee Mok (11247669)

“…Statistical significance was determined at P-value < 0.05; *, P < 0.05; **, P < 0.01; ****, P < 0.0001; ns, not significant.…”

Table 1_Weissella confusa alleviates experimental colitis in mice by regulating inflammatory pathways and gut microbiota.xlsx by Huijing Tang (19133347)

“…</p>Results<p>Compared with DSS group, W. confusa Wc1982 significantly improved the disease phenotypes of colitis mice including decreased DAI and pathological score and reduced colon shortening, decreased colonic IL-17, IL-6, and TNF-α levels and serum lipopolysaccharide (p < 0.05), and downregulated the expression of key genes of IL-17 pathway (Lcn2, Mmp3, Mmp13, Ptgs2; p < 0.05). …”

Supplementary file 1_Weissella confusa alleviates experimental colitis in mice by regulating inflammatory pathways and gut microbiota.docx by Huijing Tang (19133347)

“…</p>Results<p>Compared with DSS group, W. confusa Wc1982 significantly improved the disease phenotypes of colitis mice including decreased DAI and pathological score and reduced colon shortening, decreased colonic IL-17, IL-6, and TNF-α levels and serum lipopolysaccharide (p < 0.05), and downregulated the expression of key genes of IL-17 pathway (Lcn2, Mmp3, Mmp13, Ptgs2; p < 0.05). …”

Susceptibility of RUNX1 promoter rs2071029 polymorphism to adjuvant chemotherapy-induced neutropenia in CRC by Xikai Luo (21520875)

“…Rs2071029T promoter activity was significantly higher than that of rs2071029C promoter (<i>p</i> = 0.014). …”

Data Sheet 1_Balancing conservation and community needs: challenges, threats, and socioeconomic disparities in Kakamega Forest, Kenya.docx by Ibrahim Osewe (21460079)

“…Illegal logging emerged as the most significant threat to KFE, regardless of wealth category, followed by a lack of awareness of conservation efforts, with significant differences in perception across wealth categories. …”

Effect of Gasdermin-D inhibition on expression of phenotypic transition markers in CER treated VSMCs during Vascular Calcification. by Razia Rashid Rahil (22772495)

“…(B) Summarized bar graph showed DIS significantly decreased calcium deposition in CER treated P_i-induced VSMCs. …”

Effect of NLRP3 inhibition on expression of phenotypic transition markers in CER treated VSMCs during Vascular Calcification. by Razia Rashid Rahil (22772495)

“…(B) Summarized bar graph showed MCC950 significantly decreased calcium deposition in CER treated P_i-induced VSMCs. …”

Figure 5 from Functional Profiling of p53 and RB Cell Cycle Regulatory Proficiency Suggests Mechanism-Driven Molecular Stratification in Endometrial Carcinoma by Zelei Yang (18491142)

“…<p>Aurora kinase B inhibitor sensitive endometrial carcinoma cells show more rapidly decreasing percentages of mitotic cells than resistant models in the setting of nocodazole-induced microtubule instability. …”

Raw Data. by Hongfei Liu (1396348)

“…COS supplementation significantly increased serum superoxide dismutase activity and jejunal mucosal glutathione peroxidase activity, and significantly decreased serum malondialdehyde level (<i><i>P</i></i> < 0.05). …”

Supplementary file 1_Analysis of microbial composition in different dry skin areas of Beijing women.docx by Jingtao Wang (828021)

“…Compared to the lower leg, the back of the hand showed a higher relative abundance of Cutibacterium (34.19% vs. 8.68%), whereas the lower leg was predominantly colonized by Streptococcus (17% vs. 13.76%). At the genus level, the relative abundance of Streptococcus was significantly increased in the dry skin group, whereas a decreasing trend was observed for Cutibacterium. …”