Effect of ex vivo treatment with rhTGFβ1 or a TGFβ1 inhibitor on monocyte responses to rgE stimulation. Monocytes and NK cells purified from PBMC collected from 10 RZV recipients (demographics in S4 Table) before vaccination (D0) and 90 days post-vaccination (D90) were combined ex vivo and stimulated with VZV-rgE. A subset of D0 monocyte & NK cocultures was also treated with the TGFβ1 inhibitor LY (D0 LY), and a subset of D90 cocultures were supplemented with rhTGFβ1. The graph shows individual data points, means and p values calculated by Friedman test for repeated measures with FDR correction. LY treatment of cells collected on D0 significantly increased their activation to levels similar to D90. Conversely, treatment of D90 cells with rhTGFβ1 significantly decreased their activation to levels similar to D0. by Michael J. Johnson (5818168)

“…Conversely, treatment of D90 cells with rhTGFβ1 significantly decreased their activation to levels similar to D0.…”

The U937 cell line was seeded at 2 x 10⁵ cells per well. by Janani Madhuravasal Krishnan (19736002)

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The U937 cell line was seeded at 2 x 10⁵ cells per well. by Janani Madhuravasal Krishnan (19736002)

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U937 cells were seeded at ~1 × 10⁵ cells per well. by Janani Madhuravasal Krishnan (19736002)

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GO enrichment for the differentially expressed genes using ToppGene in U937 cells infected with HIV in the presence / absence of fentanyl. by Janani Madhuravasal Krishnan (19736002)

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The U937 cell line was seeded at 1 x 10⁴ cells per well. by Janani Madhuravasal Krishnan (19736002)

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Primary monocytes at 1 x 10⁶ cells were seeded in a flask and supplemented with RPMI 1640 + GM-CSF + IL-4 and incubated at 37°C for 6 days for monocyte to macrophage tra... by Janani Madhuravasal Krishnan (19736002)

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Differentially expressed genes in U937 cells infected with HIV in the presence / absence of fentanyl by gene function (antiviral response, cell death, chemokine signaling, interfer... by Janani Madhuravasal Krishnan (19736002)

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Mu opioid receptor (MOR) expression (pg/mL) was quantified by ELISA in 1 x 10⁵ cells resuspended in 100 μL lysis buffer and diluted 1:2. by Janani Madhuravasal Krishnan (19736002)

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The U937 cell line was seeded at 1 x 10⁵ cells per well. by Janani Madhuravasal Krishnan (19736002)

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Principle component analysis of the expression of mRNA in U937 cells in the presence / absence of fentanyl. by Janani Madhuravasal Krishnan (19736002)

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List of primers used to validate RNA sequencing data. by Janani Madhuravasal Krishnan (19736002)

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Relative change in cardiovascular diseases DALYs rates from 1990-1994 to 2017-2021 in Chile, for both genders. by Camilo Briones-Valdivieso (21567535)

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Evogliptin attenuates the phenotypic switch of VSMCs during CER treatment by decreasing the osteogenesis-associated genes <i>in-vitro.</i> by Razia Rashid Rahil (22772495)

“…(B, C) Summarized bar graph showed EVO significantly decreased calcium deposition and calcium content in CER treated P_i-induced VSMCs. …”

Mean hemoglobin levels of Roxadustat and ESAs groups over time. by Jie Liu (15128)

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Table 2_Bibliometric analysis of global research on the clinical applications of aminoglycoside antibiotics: improving efficacy and decreasing risk.docx by Tengxiang Zhao (20749475)

“…Avoiding prolonged dosing cycles and refraining from using AGs in patients with the m.1555 A > G gene variant can significantly mitigate the risk of ototoxicity. Future studies should examine the pharmacokinetic and pharmacodynamic targets of AGs and assess the efficacy and safety of administration by inhalation to improve efficacy and decrease risk.…”

Table 1_Bibliometric analysis of global research on the clinical applications of aminoglycoside antibiotics: improving efficacy and decreasing risk.docx by Tengxiang Zhao (20749475)

“…Avoiding prolonged dosing cycles and refraining from using AGs in patients with the m.1555 A > G gene variant can significantly mitigate the risk of ototoxicity. Future studies should examine the pharmacokinetic and pharmacodynamic targets of AGs and assess the efficacy and safety of administration by inhalation to improve efficacy and decrease risk.…”

Deep crypt secretory (DCS) cells are predominantly distributed in the proximal colon, with a progressive decrease towards the distal colon. by Daisuke Sugahara (2047696)

Image 2_Sediment exposure decreases diversity in the surface mucus layer microbiome of Porites lobata at Honoliʻi, Hawaiʻi.jpeg by Joseph W. P. Nakoa (21796214)

Image 3_Sediment exposure decreases diversity in the surface mucus layer microbiome of Porites lobata at Honoliʻi, Hawaiʻi.jpeg by Joseph W. P. Nakoa (21796214)