Trends in voluntary disclosure report names for Japanese Listed Companies 2008-2023. by Yuichiro Nakai (689312)

“…<p>This figure highlights the significant increase in the number of Integrated Reports and Company Name Reports, as well as the notable decrease in the number of Annual Reports issued by Japanese listed companies from 2008 to 2023.…”

Image 2_Hemoglobin glycation index and all-cause mortality in adults: insights from a decade-long prospective cohort study.tif by Yue-Yang Zhang (14258160)

“…After COX regression, restricted cubic spline analysis, and subgroup analyses, it was found that a significant increase or decrease in HGI adversely affected long-term survival.…”

Image 1_Hemoglobin glycation index and all-cause mortality in adults: insights from a decade-long prospective cohort study.tif by Yue-Yang Zhang (14258160)

“…After COX regression, restricted cubic spline analysis, and subgroup analyses, it was found that a significant increase or decrease in HGI adversely affected long-term survival.…”

Data Sheet 1_Synergistic inhibition of Aspergillus flavus by organic acid salts: growth, oxidative stress, and aflatoxin gene modulation.docx by Yingying Yu (546494)

“…Compared to the control group, the MIC group of the composite organic acid salt significantly reduced the relative expression levels of genes encoding the aflatoxin synthesis pathway, including aflR, aflS, aflC, aflD, aflT, and aflM genes. …”

Sleep deprivation by payam saidie (20329440)

“…Furthermore, in the NSP group, a significant decrease was observed at BASE compared to 60 min-PS (P ≤ 0.05) (20.72%).…”

Table 1_Elucidating the effects of nine-steaming-nine-drying on the morphology, metabolomic profile, and active ingredients of Polygonatum sibiricum Redouté.xls by Rui Wang (52434)

“…These alterations resulted in darker coloration, as evidenced by a significant decrease in L* values, elimination of tongue-numbing effects, enhanced sweetness, and improved quality of P. sibiricum Red. …”

Supplementary file 1_Mortality trends in extremely premature neonates: insights from the CDC WONDER database from 1999 to 2023.docx by Rebecca Hammond (838344)

“…</p>Results<p>Extreme immaturity resulted in 92,917 deaths among neonates in their first year of life from 1999 to 2023. Overall CMR significantly decreased across the study period [AAPC −1.14* 95% CI (−1.45, −0.83)], with both female and male neonates experiencing a significant decrease in CMR [AAPC −1.32* 95% CI [−1.63, −1.06] and AAPC −1.10* 95% CI [−1.57, −0.68] respectively]. …”

Data Sheet 2_Effect of SY009, a novel SGLT1 inhibitor, on the plasma metabolome and bile acids in patients with type 2 diabetes mellitus.docx by Haoyi Yang (8215116)

“…</p>Results<p>Untargeted metabolomics revealed that, after SY009 treatment, there were differences in metabolic pathways, including primary bile acid biosynthesis; biosynthesis of unsaturated fatty acid; steroid hormone biosynthesis; purine metabolism; phenylalanine, tyrosine and tryptophan biosynthesis. In particular, the increase in bile acid-related metabolites in the 2 mg BID group was significantly greater than that in the placebo group, and unsaturated fatty acid-related metabolites decreased in both the 2 mg BID group and the placebo group, but there was no significant difference between the two groups. …”

Data Sheet 1_Effect of SY009, a novel SGLT1 inhibitor, on the plasma metabolome and bile acids in patients with type 2 diabetes mellitus.docx by Haoyi Yang (8215116)

“…</p>Results<p>Untargeted metabolomics revealed that, after SY009 treatment, there were differences in metabolic pathways, including primary bile acid biosynthesis; biosynthesis of unsaturated fatty acid; steroid hormone biosynthesis; purine metabolism; phenylalanine, tyrosine and tryptophan biosynthesis. In particular, the increase in bile acid-related metabolites in the 2 mg BID group was significantly greater than that in the placebo group, and unsaturated fatty acid-related metabolites decreased in both the 2 mg BID group and the placebo group, but there was no significant difference between the two groups. …”

Data Sheet 1_Incidence of hyperkalemia RAASi and SGLT-2i treatment in individuals with diabetic kidney disease: a systematic review and network meta-analysis.docx by Yahui Yuan (12112503)

“…SGLT-2i (SUCRA = 88.5%) was found to significantly reduce the risk of hyperkalemia. In contrast, the combination of ACEI/ARB + MRA (SUCRA = 5.7%) increased the risk of hyperkalemia. …”

Liquid mosquito repellent induces toxic effects in zebrafish by Gokul Sudhakaran (18870829)

“…While these products demonstrate significant efficacy, the toxicological implications associated with their use are not yet fully understood and continue to be a subject of debate. …”

<b>Empagliflozin Enhances Hepatic Glucose Production and Reduces Total-Body Norepinephrine Turnover Rate:</b> <b>A Randomized Trial</b> by Siham Abdelgani (17756772)

“…Total-body NE turnover significantly decreased in both groups at one day after empagliflozin administration, and the decrease in NE turnover persisted for 12 weeks. …”

Table 2_Factors influencing bone mineral density in hyperparathyroidism phenotypes: a prospective study.xlsx by Margot Giocondo (21435500)

“…This condition is characterized by inappropriately elevated parathyroid hormone (PTH) levels relative to serum calcium levels, leading to high bone turnover and decreased bone mineral density (BMD). …”

Table 1_Factors influencing bone mineral density in hyperparathyroidism phenotypes: a prospective study.xlsx by Margot Giocondo (21435500)

“…This condition is characterized by inappropriately elevated parathyroid hormone (PTH) levels relative to serum calcium levels, leading to high bone turnover and decreased bone mineral density (BMD). …”

Data Sheet 1_Empagliflozin’s cardioenergetic protective effects through PPARα pathway modulation in heart failure.pdf by Hua Wei (60877)

“…Post-treatment, MRGlu and glucose uptake decreased markedly in the empagliflozin (EMPG) group, while no significant changes were observed in the fenofibrate (FF) group. …”

Data_Sheet_2_Causal relationship between non-alcoholic fatty liver disease and sarcopenia: a bidirectional Mendelian randomization study.PDF by Meng Chen (48769)

“…Published summary statistics were used to obtain instrumental variables (IVs) at the genome-wide significance level.</p>Results<p>IVW analysis showed that the risk of NAFLD was reduced when walking pace was increased (OR = 0.435, 95%CI 0.240–0.789, p = 0.006); Increasing appendicular lean mass (ALM) decreased the risk of NAFLD (OR = 0.906, 95%CI 0.838–0.980, p = 0.014); Those older than 60 were more likely to suffer from NAFLD if they had low grip strength (OR = 1.411, 95%CI 1.087–1.830, p = 0.0012). …”

Data_Sheet_1_Causal relationship between non-alcoholic fatty liver disease and sarcopenia: a bidirectional Mendelian randomization study.PDF by Meng Chen (48769)

“…Published summary statistics were used to obtain instrumental variables (IVs) at the genome-wide significance level.</p>Results<p>IVW analysis showed that the risk of NAFLD was reduced when walking pace was increased (OR = 0.435, 95%CI 0.240–0.789, p = 0.006); Increasing appendicular lean mass (ALM) decreased the risk of NAFLD (OR = 0.906, 95%CI 0.838–0.980, p = 0.014); Those older than 60 were more likely to suffer from NAFLD if they had low grip strength (OR = 1.411, 95%CI 1.087–1.830, p = 0.0012). …”

Table_1_Causal relationship between non-alcoholic fatty liver disease and sarcopenia: a bidirectional Mendelian randomization study.DOCX by Meng Chen (48769)

“…Published summary statistics were used to obtain instrumental variables (IVs) at the genome-wide significance level.</p>Results<p>IVW analysis showed that the risk of NAFLD was reduced when walking pace was increased (OR = 0.435, 95%CI 0.240–0.789, p = 0.006); Increasing appendicular lean mass (ALM) decreased the risk of NAFLD (OR = 0.906, 95%CI 0.838–0.980, p = 0.014); Those older than 60 were more likely to suffer from NAFLD if they had low grip strength (OR = 1.411, 95%CI 1.087–1.830, p = 0.0012). …”

Table 1_Investigating the psychophysiological effects of NaiKan Therapy: salivary oxytocin and cortisol release.docx by Ming Qian (429232)

“…Our results revealed significant increases in salivary oxytocin levels following NaiKan Therapy, suggesting a potential role of this practice in enhancing social bonding and emotional regulation. …”

Table 2_Investigating the psychophysiological effects of NaiKan Therapy: salivary oxytocin and cortisol release.xlsx by Ming Qian (429232)

“…Our results revealed significant increases in salivary oxytocin levels following NaiKan Therapy, suggesting a potential role of this practice in enhancing social bonding and emotional regulation. …”