Molecular-docking simulation of the TsSPc–CK8 complex in Caco-2 cells. by Wen Wen Zheng (17721404)

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CK8 knockdown and ROCK1 inhibitor abolished rTsSPc-reduced TJs expression in Caco-2 monolayers by IFA. by Wen Wen Zheng (17721404)

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PAS staining of intestinal sections from <i>T. spiralis</i>-infected mice pretreated with DAS and Y27632. by Wen Wen Zheng (17721404)

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qPCR and Western blotting of CK8 knockdown blocking the rTsSPc-activated pathway and -reduced TJs expression. by Wen Wen Zheng (17721404)

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IFA, GST pull-down and Co-IP assay of specific binding between rTsSPc and CK8. by Wen Wen Zheng (17721404)

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qPCR and Western blotting of activation of CK8 receptor and RhoA/ROCK1 pathway proteins in Caco-2 cells treated with rTsSPc and IIL ES antigens. by Wen Wen Zheng (17721404)

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CK8 knockdown and ROCK1 inhibitor suppressed rTsSPc-induced disruption of the Caco-2 monolayer and blocked rTsSPc-promoted IIL invasion. by Wen Wen Zheng (17721404)

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Intraperitoneal injection protocol for inhibitors (A), inhibitors DAS and Y27632 reduced intestinal permeability (B) and intestinal adult worm burden (C) of infected mice. by Wen Wen Zheng (17721404)

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HE staining showed that DAS and Y27632 alleviated intestinal inflammation in <i>T. spiralis</i>-infected mice. by Wen Wen Zheng (17721404)

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The ROCK1 pathway inhibitor Y27632 prevented rTsSPc from activating the ROCK1 pathway and reducing TJs expression. by Wen Wen Zheng (17721404)

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qPCR (A-D) and ELISA (E-H) detection of inflammatory cytokines in intestine of <i>T. spiralis</i>-infected mice. by Wen Wen Zheng (17721404)

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Protein differential analysis list. by Miao Cheng (4348510)

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Effects of NMRAL1 siRNA transfection on the expression of inflammatory cytokines in RAW264.7 macrophages. by Miao Cheng (4348510)

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KEGG pathway enrichment bubble plot of differentially expressed proteins between groups. by Miao Cheng (4348510)

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Venn diagram illustrating common and unique DEPs across group comparisons. by Miao Cheng (4348510)

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Effect of NMRAL1 siRNA transfection on NMRAL1 mRNA expression in RAW264.7 macrophages. by Miao Cheng (4348510)

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Quantitative analysis. by Miao Cheng (4348510)

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Protein identification results. by Miao Cheng (4348510)

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Basic characteristics of the participants with intestinal mucosal specimens collected. by Miao Cheng (4348510)

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GO annotations of differentially expressed proteins between groups. by Miao Cheng (4348510)

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