Supplementary file 1_HuangLian-4 alleviates myocardial ischemia-reperfusion injury by activating the pro-survival STAT3 signaling pathway.doc by Chelimuge Gong (22563287)

“…Mechanistically, our primary finding revealed that HL4 markedly rescued the H/R-induced downregulation of the pro-survival factor STAT3 at both the mRNA and protein levels. This activation of STAT3 was accompanied by a significant increase in the anti-apoptotic protein Bcl-2 and a decrease in pro-apoptotic Bax, alongside the suppression of the maladaptive factor HIF-1α. …”

Image 1_Exploring the associations of gut microbiota with inflammatory and the early hematoma expansion in intracerebral hemorrhage: from change to potential therapeutic objectives... by Haixiao Jiang (12013904)

“…</p>Results<p>Our findings showed a significant decrease in the diversity and even distribution of microorganisms in the HE group when compared to the HC and NE groups. …”

Table1_The clinical and genetic aspects of six individuals with GH1 variants and isolated growth hormone deficiency type II.docx by Xiaozhen Huang (5858690)

“…Background<p>Isolated growth hormone deficiency type II (IGHD II) is an autosomal dominant disorder characterized by a GH1 gene variant resulting in a significant reduction in growth hormone (GH) secretion and a subsequent decrease of plasma insulin-like growth factor 1 (IGF-1) levels and eventual growth impairment.…”

Trends in voluntary disclosure report names for Japanese Listed Companies 2008-2023. by Yuichiro Nakai (689312)

“…<p>This figure highlights the significant increase in the number of Integrated Reports and Company Name Reports, as well as the notable decrease in the number of Annual Reports issued by Japanese listed companies from 2008 to 2023.…”

Sleep deprivation by payam saidie (20329440)

“…Furthermore, in the NSP group, a significant decrease was observed at BASE compared to 60 min-PS (P ≤ 0.05) (20.72%).…”

Table 1_Elucidating the effects of nine-steaming-nine-drying on the morphology, metabolomic profile, and active ingredients of Polygonatum sibiricum Redouté.xls by Rui Wang (52434)

“…These alterations resulted in darker coloration, as evidenced by a significant decrease in L* values, elimination of tongue-numbing effects, enhanced sweetness, and improved quality of P. sibiricum Red. …”

Supplementary file 1_The impact of COVID-19 on thyroid function and psychological state of Graves’ disease: a one-year prospective study.jpeg by Lujia Xu (6912416)

“…At 3 months post-infection, the G3 group showed an increased FT3/FT4 ratio and decreased FT4 levels. Significant intergroup differences were observed in FT4 and TSH changes from pre-infection levels, with the G3 group having the highest anxiety and depression scores. …”

Supplementary file 2_The impact of COVID-19 on thyroid function and psychological state of Graves’ disease: a one-year prospective study.jpeg by Lujia Xu (6912416)

“…At 3 months post-infection, the G3 group showed an increased FT3/FT4 ratio and decreased FT4 levels. Significant intergroup differences were observed in FT4 and TSH changes from pre-infection levels, with the G3 group having the highest anxiety and depression scores. …”

Supplementary file 1_Mortality trends in extremely premature neonates: insights from the CDC WONDER database from 1999 to 2023.docx by Rebecca Hammond (838344)

“…</p>Results<p>Extreme immaturity resulted in 92,917 deaths among neonates in their first year of life from 1999 to 2023. Overall CMR significantly decreased across the study period [AAPC −1.14* 95% CI (−1.45, −0.83)], with both female and male neonates experiencing a significant decrease in CMR [AAPC −1.32* 95% CI [−1.63, −1.06] and AAPC −1.10* 95% CI [−1.57, −0.68] respectively]. …”

Data Sheet 1_Exploring the relationship between occupational stress, physical activity and sedentary behavior using the Job-Demand-Control Model.docx by Maëlys Clinchamps (11080212)

“…Job strain was associated with increased sitting time and decreased physical activity. …”

Data Sheet 1_Fatty infiltration and cross-sectional area as indicators of muscle mass in osteoporosis: a meta-regression study.pdf by Genwen Sun (22678739)

“…Meta-regression identified age as a significant moderator, indicating that morphological differences diminish with increasing age. …”

Data Sheet 2_Role of CDH1 gene variants and E-cadherin localization in gastric mucosal cancerization.docx by Yunbo Wu (9127390)

“…Localization analysis revealed decreased membrane-bound E-cadherin with increased cytoplasmic expression as lesion severity increased. …”

Data Sheet 1_Role of CDH1 gene variants and E-cadherin localization in gastric mucosal cancerization.pdf by Yunbo Wu (9127390)

“…Localization analysis revealed decreased membrane-bound E-cadherin with increased cytoplasmic expression as lesion severity increased. …”

Table 1_Enhancement of prefrontal functional connectivity under the influence of concurrent physical load during mental tasks.docx by Shan Cheng (1569355)

“…</p>Results<p>On the basis of effects of cognitive tasks, the concurrent physical activities would further increase National Aeronautics and Space Administration Task Load Index score (p < 0.05) and decrease task performance (p < 0.05). …”

<b>Empagliflozin Enhances Hepatic Glucose Production and Reduces Total-Body Norepinephrine Turnover Rate:</b> <b>A Randomized Trial</b> by Siham Abdelgani (17756772)

“…Total-body NE turnover significantly decreased in both groups at one day after empagliflozin administration, and the decrease in NE turnover persisted for 12 weeks. …”

Image 3_Benign regulation of short-chain fatty acids: the underlying mechanism of the beneficial effects of manual acupuncture on cognitive ability and the intestinal mucosal barri... by Ning Ding (456674)

“…</p>Results<p>Compared with those in the C57BL/6 control (Cc) group, cognitive ability was significantly decreased, SCFAs and FFAR3 expression were obviously decreased, intestinal barrier integrity was drastically impaired, and the expression of NF-κB and the levels of intestinal IL-1β and TNF-α were increased in the APP/PS1 control (Ac) group. …”

Image 1_Benign regulation of short-chain fatty acids: the underlying mechanism of the beneficial effects of manual acupuncture on cognitive ability and the intestinal mucosal barri... by Ning Ding (456674)

“…</p>Results<p>Compared with those in the C57BL/6 control (Cc) group, cognitive ability was significantly decreased, SCFAs and FFAR3 expression were obviously decreased, intestinal barrier integrity was drastically impaired, and the expression of NF-κB and the levels of intestinal IL-1β and TNF-α were increased in the APP/PS1 control (Ac) group. …”

Image 4_Benign regulation of short-chain fatty acids: the underlying mechanism of the beneficial effects of manual acupuncture on cognitive ability and the intestinal mucosal barri... by Ning Ding (456674)

“…</p>Results<p>Compared with those in the C57BL/6 control (Cc) group, cognitive ability was significantly decreased, SCFAs and FFAR3 expression were obviously decreased, intestinal barrier integrity was drastically impaired, and the expression of NF-κB and the levels of intestinal IL-1β and TNF-α were increased in the APP/PS1 control (Ac) group. …”

Table 1_Benign regulation of short-chain fatty acids: the underlying mechanism of the beneficial effects of manual acupuncture on cognitive ability and the intestinal mucosal barri... by Ning Ding (456674)

“…</p>Results<p>Compared with those in the C57BL/6 control (Cc) group, cognitive ability was significantly decreased, SCFAs and FFAR3 expression were obviously decreased, intestinal barrier integrity was drastically impaired, and the expression of NF-κB and the levels of intestinal IL-1β and TNF-α were increased in the APP/PS1 control (Ac) group. …”

Image 2_Benign regulation of short-chain fatty acids: the underlying mechanism of the beneficial effects of manual acupuncture on cognitive ability and the intestinal mucosal barri... by Ning Ding (456674)

“…</p>Results<p>Compared with those in the C57BL/6 control (Cc) group, cognitive ability was significantly decreased, SCFAs and FFAR3 expression were obviously decreased, intestinal barrier integrity was drastically impaired, and the expression of NF-κB and the levels of intestinal IL-1β and TNF-α were increased in the APP/PS1 control (Ac) group. …”