Showing 21,221 - 21,240 results of 24,497 for search '(( significant ((linear decrease) OR (greater disease)) ) OR ( significant decrease decrease ))', query time: 0.65s Refine Results
  1. 21221
  2. 21222

    Data Sheet 1_Metformin upregulates circadian gene PER2 to inhibit growth and enhance the sensitivity of glioblastoma cell lines to radiotherapy via SIRT2/G6PD pathway.docx by Hailiang Li (740080)

    Published 2025
    “…Meanwhile, NADPH+ production and G6PDH enzyme activity significantly decreased. Further study validated that metformin inhibited the cell growth of GBM cell lines through up-regulating PER2 and inhibited SIRT2/G6PD signaling pathway, enhancing radiotherapy(RT) sensitivity. …”
  3. 21223

    Table8_Unveiling the molecular landscape of PCOS: identifying hub genes and causal relationships through bioinformatics and Mendelian randomization.xlsx by Yifang He (18126257)

    Published 2024
    “…</p>Conclusions<p>Our bioinformatics combined with MR analysis revealed that CD93, CYBB, DOCK8, IRF1, MBOAT1, MYO1F, NLRP1, NOD2, PIK3R1 increase the risk of PCOS, while PTER decreases the risk of PCOS. This discovery has implications for clinical decision-making in terms of disease diagnosis, prognosis, treatment strategies, and opens up novel avenues for drug development.…”
  4. 21224

    The performance of S-YOFEO model on MOT17. by Wenshun Sheng (21485393)

    Published 2025
    “…OSA is highly sensitive to information of different scales, and its one-time aggregation property substantially decreases the computational overhead of the model. …”
  5. 21225
  6. 21226

    Table5_Unveiling the molecular landscape of PCOS: identifying hub genes and causal relationships through bioinformatics and Mendelian randomization.xlsx by Yifang He (18126257)

    Published 2024
    “…</p>Conclusions<p>Our bioinformatics combined with MR analysis revealed that CD93, CYBB, DOCK8, IRF1, MBOAT1, MYO1F, NLRP1, NOD2, PIK3R1 increase the risk of PCOS, while PTER decreases the risk of PCOS. This discovery has implications for clinical decision-making in terms of disease diagnosis, prognosis, treatment strategies, and opens up novel avenues for drug development.…”
  7. 21227

    DataSheet1_Probiotics combined with prebiotics alleviated seasonal allergic rhinitis by altering the composition and metabolic function of intestinal microbiota: a prospective, ran... by Yangfan Hou (8043884)

    Published 2024
    “…From baseline to day 91, mean difference between groups (MDBG) in the reduction of TNSS was -1.1 (-2.2, -0.1) (P = 0.04); MDBG in the increment of TNF-α was 7.1 pg/ml (95% CI: 0.8, 13.4, P = 0.03); the INF-γ level was significantly increased (P = 0.01), whereas that of IL-17 (P = 0.005) was significantly decreased in the test group, whilst mean difference within groups was not statistically significant in the placebo group; MDBG in the increment of acetate was 12.4% (95% CI: 7.1%, 17.6%, P <0.001). …”
  8. 21228

    Table 1_Evaluating the Implementation of fan-beam CT-guided online adaptive re-planning in definitive cervical cancer radiotherapy.docx by Shuai Sun (775057)

    Published 2025
    “…This approach has shown significant improvements in dose distribution and the potential to provide clinical benefits by reducing acute toxicity.…”
  9. 21229

    Five multi-target tracking evaluation indexes. by Wenshun Sheng (21485393)

    Published 2025
    “…OSA is highly sensitive to information of different scales, and its one-time aggregation property substantially decreases the computational overhead of the model. …”
  10. 21230

    Data Sheet 2_Cellular effects of splenectomy on liver regeneration after 70% resection.pdf by Andrey Elchaninov (3122742)

    Published 2025
    “…Splenectomy also correlated with decreased rates of Ly6C+ monocyte and Ly6G+ leukocyte migration. …”
  11. 21231

    Genetic and structural factors contributing to the dominance and persistence of goose astrovirus type 2 by Peng Jiang (16544)

    Published 2025
    “…<p>Goose astrovirus (GoAstV) has emerged as a significant pathogen affecting the goose industry in China, with GoAstV-2 becoming the dominant genotype since 2017. …”
  12. 21232

    Care quality. by Youssef Hbid (18803761)

    Published 2025
    “…<div><p>Background and aim</p><p>The COVID-19 pandemic imposed significant pressures on healthcare services such as stroke care. …”
  13. 21233
  14. 21234

    Glucagon-like peptide 1 receptor agonists modestly reduced low-density lipoprotein cholesterol and total cholesterol levels independent of weight reduction: a meta-analysis and met... by Frederick Berro Rivera (12679463)

    Published 2024
    “…</p> <p>GLP-1RA treatment modestly decreased LDL-C and TC but did not significantly affect triglycerides, VLDL-C, or HDL-C.…”
  15. 21235

    Image 1_Dysfunctional β-cell autophagy induces β-cell stress and enhances islet immunogenicity.tiff by Matthew C. Austin (20633168)

    Published 2025
    “…Gene ontology analysis revealed a significant upregulation of pathways involved in inflammatory processes, response to ER stress, and the ER-associated degradation pathway. …”
  16. 21236

    Algorithm flowchart of OFEO. by Wenshun Sheng (21485393)

    Published 2025
    “…OSA is highly sensitive to information of different scales, and its one-time aggregation property substantially decreases the computational overhead of the model. …”
  17. 21237

    Data Sheet 1_Cellular effects of splenectomy on liver regeneration after 70% resection.pdf by Andrey Elchaninov (3122742)

    Published 2025
    “…Splenectomy also correlated with decreased rates of Ly6C+ monocyte and Ly6G+ leukocyte migration. …”
  18. 21238

    Image 1_Kidney sparing surgery versus radical nephroureterectomy in upper tract urothelial carcinoma: a meta-analysis and systematic review.tif by Leqing Zhou (20981021)

    Published 2025
    “…In the comparison between the endoscopic management (EM) and RNU groups, EM was associated with worse overall survival outcomes (HR,1.40; 95%CI,1.08-1.82; P=0.01) based on multivariable Cox regression analysis, and the upper tract recurrence rate (OR,39.06; 95%CI, 14.55-104.85; P<0.00001) was significantly higher in the EM group. On the other hand, in patients treated with KSS, postoperative renal function as measured by eGFR increased by 0.4ml/min/1.73 m<sup>2</sup>, while it decreased by 11.4ml/min/1.73 m<sup>2</sup> in the RNU group (WMD, 11.81 ml/min/1.73 m<sup>2</sup>; 95%CI,9.06-14.56; P<0.0001).…”
  19. 21239

    Data Sheet 1_The impact of immune checkpoint inhibitors on prognosis in unresectable hepatocellular carcinoma treated with TACE and lenvatinib: a meta-analysis.zip by Wei Zhang (405)

    Published 2025
    “…The TACE+L+I group had a significantly higher incidence of hypothyroidism compared to the TACE+L group (RR = 1.81, 95%CI:1.20, 2.71, p<0.05), but there was no significant difference in other adverse events, such as hypertension, diarrhea, hand-foot syndrome, fatigue, elevated AST, elevated ALT, decreased appetite, hypothyroidism, abdominal pain, thrombocytopenia, rash, and nausea.…”
  20. 21240

    Outcomes at discharge. by Youssef Hbid (18803761)

    Published 2025
    “…<div><p>Background and aim</p><p>The COVID-19 pandemic imposed significant pressures on healthcare services such as stroke care. …”