يعرض 20,161 - 20,180 نتائج من 23,970 نتيجة بحث عن '(( significant ((linear increase) OR (greatest decrease)) ) OR ( significant decrease decrease ))', وقت الاستعلام: 0.45s تنقيح النتائج
  1. 20161

    Image 2_Global burden of varicella and herpes zoster across 204 countries, 1990–2021: a temporal trend analysis in the era of the COVID-19 pandemic and projections to 2036.tiff حسب Zilun Wu (18696883)

    منشور في 2025
    "…Mortality and DALYs declined significantly, with age-standardized mortality rates (ASMR) and DALYs rates (ASDR) decreasing by 50.0 and 36.3%, respectively. …"
  2. 20162

    Data Sheet 1_Factors influencing, and associated with, physical activity patterns in dogs with osteoarthritis-associated pain.xlsx حسب Christina Stevens (9737867)

    منشور في 2025
    "…</p>Results<p>At times of peak activity within a 24-h period, dogs with hindlimb OA pain, higher age, higher Clinical Metrology Instrument scores, higher joint pain, greater Body Condition Score and greater muscle atrophy all had decreased activity profiles. However, only age, hindlimb joint pain, and hindlimb muscle atrophy had statistically significant effects on physical activity.…"
  3. 20163

    Table 11_Identification and validation for biomarkers associated with mitochondrial metabolism in chronic obstructive pulmonary disease.xlsx حسب Wenjun Wang (314231)

    منشور في 2025
    "…The mRNA and protein expression of APRT and LCAT were significantly decreased in COPD patients’ lung tissues.…"
  4. 20164

    Table 1_Brown adipocyte exosome - derived C22:6 inhibits the IL-1β signaling pathway to alleviate rheumatoid arthritis.docx حسب Rui Jiang (264894)

    منشور في 2025
    "…Introduction<p>Rheumatoid arthritis (RA) is an autoimmune disorder characterized by significant disability and teratogenic effects, for which there are few effective curative therapies. …"
  5. 20165

    Main module structure. حسب Dunlu Lu (19964225)

    منشور في 2024
    "…At the same time, the model size was reduced by 9.3%, and the number of model layers was decreased, reducing computational costs and storage requirements. …"
  6. 20166

    Data Sheet 5_CD44 knockdown alters miRNA expression and their target genes in colon cancer.zip حسب Diana Maltseva (11678641)

    منشور في 2025
    "…Introduction<p>Metastasis formation poses a significant challenge to oncologists, as it severely limits the survival of colorectal cancer (CRC) patients. …"
  7. 20167

    Supplementary Material for: Efficacy of penetrating canaloplasty versus trabeculectomy in patients with bilateral primary glaucoma: a self-control study حسب figshare admin karger (2628495)

    منشور في 2025
    "…Although not statistically significant, higher qualified success was observed in TRAB (96.0%) than in PCP group (88.0%, p=0.609) at 12 month. …"
  8. 20168

    DataSheet1_Associations of serum folate and vitamin B12 levels with all-cause mortality among patients with metabolic dysfunction associated steatotic liver disease: a prospective... حسب Jiaxin Zhu (446571)

    منشور في 2024
    "…When their serum concentrations were below the median level, the risk of all-cause mortality decreased with increasing concentration, reaching a lowest risk around the median level, and then leveled off. …"
  9. 20169

    Image 2_Beta-hydroxybutyrate (BHB) elicits concentration-dependent anti-inflammatory effects on microglial cells which are reversible by blocking its monocarboxylate (MCT) importer... حسب Chase Garcia (21803576)

    منشور في 2025
    "…</p>Results<p>At this concentration, BHB significantly and concentration-dependently decreased the following: 1) inflammatory cytokine expression (IL-6, TNF-α, and IL-1β), 2) inflammatory morphological changes, and 3) activation of p-ERK and p-p38MAPK, which are key pathways involved in microglial inflammation. …"
  10. 20170

    Table 1_Blue and red LEDs modulate polyphenol production in Precoce and Tardiva cultivars of Cichorium intybus L..docx حسب Felicia Menicucci (7495508)

    منشور في 2025
    "…The polyphenolic composition of the two cultivars significantly changed depending on the type of LEDs used. …"
  11. 20171

    Table 3_Antifungal mechanism and transcriptome analysis of Bacillomycin D-C16 against Fusarium oxysporum.xlsx حسب Fuxing Lin (7418234)

    منشور في 2025
    "…Furthermore, nearly all DEGs related to DNA replication were significantly suppressed. Biochemical assays confirmed these observations: Reduced activities of mitochondrial enzymes [malate dehydrogenase (MDH), isocitrate dehydrogenase (IDH), pyruvate dehydrogenase (PDH), and complexes I–V], decreased mitochondrial membrane potential, and diminished ATP content collectively indicated mitochondrial dysfunction. …"
  12. 20172

    Table 7_Identification and validation for biomarkers associated with mitochondrial metabolism in chronic obstructive pulmonary disease.xlsx حسب Wenjun Wang (314231)

    منشور في 2025
    "…The mRNA and protein expression of APRT and LCAT were significantly decreased in COPD patients’ lung tissues.…"
  13. 20173

    Table 1_An alternative structured weight management protocol to rapid weight loss in mixed martial arts: a prospective interventional study of pre-competition weight management str... حسب Clóvis Albuquerque Maurício (22389121)

    منشور في 2025
    "…Starting 7 days before the weigh-in, athletes consumed 7 liters of fluids per day, with intake gradually decreasing. On the day before the weigh-in, they consumed only 0.5 liters. …"
  14. 20174
  15. 20175

    Image 3_Club cell-derived brain-derived neurotrophic factor regulates murine airway mechanics and mucin production in response to IL-13 in a sex-dependent manner.jpeg حسب Amy Fagan (17678004)

    منشور في 2025
    "…No statistically significant differences were observed in pulmonary mechanics between male mice with or without conditional loss of epithelial cell Bdnf, although treatment effects of IL-13 were noted. …"
  16. 20176

    Dependent and independent variables (N = 316). حسب Priyanka Saluja (20501044)

    منشور في 2025
    "…<div><p>Introduction</p><p>Unmet oral health needs remain a significant issue among immigrant adolescents, often exacerbated by experiences of racial discrimination. …"
  17. 20177

    Image 1_Beta-hydroxybutyrate (BHB) elicits concentration-dependent anti-inflammatory effects on microglial cells which are reversible by blocking its monocarboxylate (MCT) importer... حسب Chase Garcia (21803576)

    منشور في 2025
    "…</p>Results<p>At this concentration, BHB significantly and concentration-dependently decreased the following: 1) inflammatory cytokine expression (IL-6, TNF-α, and IL-1β), 2) inflammatory morphological changes, and 3) activation of p-ERK and p-p38MAPK, which are key pathways involved in microglial inflammation. …"
  18. 20178

    DataSheet2_Mechanism of Valeriana officinalis L. extract improving atherosclerosis by regulating PGC-1α/Sirt3/Epac1 pathway.pdf حسب Bo Yao (308010)

    منشور في 2024
    "…Furthermore, the drug significantly increased the mRNA and protein expression of PGC-1α and Sirt3 in aortic tissue, while decreasing the mRNA and protein expression of Epac1, Caspase-3, and Caspase-9.…"
  19. 20179

    Supplementary file 1_Emergency department overcrowding: first Swiss application of the Emergency Department Work Index and risk factors for overcrowding.pdf حسب Aline Herzog (22589720)

    منشور في 2025
    "…Introduction<p>Emergency department (ED) overcrowding is associated with increased waiting time, reduced patient satisfaction, and decreased quality of care. Numerous validated scores are available for assessing ED overcrowding. …"
  20. 20180

    Table 2_Global burden and future trends of gastric cancer in women of reproductive age: estimates from the GBD 2021 Study, 1990–2050.xlsx حسب Nan Jiang (21252)

    منشور في 2025
    "…Although incidence is higher in men, GC remains a significant health issue for women of reproductive age (15–49 years) due to biological, hormonal, and socioeconomic factors. …"