يعرض 18,041 - 18,060 نتائج من 21,342 نتيجة بحث عن '(( significant ((main decrease) OR (mean decrease)) ) OR ( significant decrease decrease ))', وقت الاستعلام: 0.69s تنقيح النتائج
  1. 18041

    Table 1_Multi-omics identification and validation of oxidative phosphorylation–related hub genes in schizophrenia.docx حسب Yu Zhou (89766)

    منشور في 2025
    "…Extending these findings in vivo, MK-801–treated mice exhibited behavioral and neuronal deficits, reduced ATP5A fluorescence intensity, and decreased ATP concentrations; expression of all four hub genes was significantly altered, with three (MALAT1, PPIL3, and ITM2A) concordant with transcriptomic results. …"
  2. 18042

    Table 6_Antifungal mechanism and transcriptome analysis of Bacillomycin D-C16 against Fusarium oxysporum.xlsx حسب Fuxing Lin (7418234)

    منشور في 2025
    "…Furthermore, nearly all DEGs related to DNA replication were significantly suppressed. Biochemical assays confirmed these observations: Reduced activities of mitochondrial enzymes [malate dehydrogenase (MDH), isocitrate dehydrogenase (IDH), pyruvate dehydrogenase (PDH), and complexes I–V], decreased mitochondrial membrane potential, and diminished ATP content collectively indicated mitochondrial dysfunction. …"
  3. 18043

    Prognostic value of cardiac troponin I in acute ischemic stroke patients treated with reperfusion therapy: a multicenter retrospective cohort study حسب Andrea Loggini (12077927)

    منشور في 2025
    "…Elevated cTnI was not significantly associated with sICH (OR:3.75, 95%CI 0.52–27.21, <i>p</i> = 0.19), but was independently associated with increased in-hospital mortality (OR:1.96, 95%CI 1.62–6.20, <i>p</i> = 0.025) and decreased odds of good functional outcome at 30 days (OR:0.40, 95%CI 0.19–0.84, <i>p</i> = 0.016). …"
  4. 18044

    Table1_Identifying new biomarkers and potential therapeutic targets for breast cancer through the integration of human plasma proteomics: a Mendelian randomization study and coloca... حسب Jingshuang Song (11340138)

    منشور في 2024
    "…While some targeted therapies have been developed, there are still significant challenges in early diagnosis and treatment, highlighting the need to identify new biomarkers and therapeutic targets for breast cancer. …"
  5. 18045

    DataSheet1_Identifying new biomarkers and potential therapeutic targets for breast cancer through the integration of human plasma proteomics: a Mendelian randomization study and co... حسب Jingshuang Song (11340138)

    منشور في 2024
    "…While some targeted therapies have been developed, there are still significant challenges in early diagnosis and treatment, highlighting the need to identify new biomarkers and therapeutic targets for breast cancer. …"
  6. 18046

    Image2_Chaihu Shugan powder restores fatty acid synthesis to alleviate insulin resistance in metabolic syndrome by regulating the LXRα/SREBP-1 signaling pathway.TIF حسب Sisi Lei (10999575)

    منشور في 2024
    "…Background<p>Metabolic syndrome (MS) is a significant risk factor for cardiovascular and cerebrovascular diseases, primarily driven by insulin resistance (IR). …"
  7. 18047

    Table 5_Antifungal mechanism and transcriptome analysis of Bacillomycin D-C16 against Fusarium oxysporum.xlsx حسب Fuxing Lin (7418234)

    منشور في 2025
    "…Furthermore, nearly all DEGs related to DNA replication were significantly suppressed. Biochemical assays confirmed these observations: Reduced activities of mitochondrial enzymes [malate dehydrogenase (MDH), isocitrate dehydrogenase (IDH), pyruvate dehydrogenase (PDH), and complexes I–V], decreased mitochondrial membrane potential, and diminished ATP content collectively indicated mitochondrial dysfunction. …"
  8. 18048

    Image 1_Prognostic model construction and immune microenvironment analysis of pyroptosis-related genes in hepatocellular carcinoma based on single-cell RNA sequencing.tiff حسب Haoming Shen (3816988)

    منشور في 2025
    "…Although pyroptosis plays a critical role in tumor-immune interactions, its prognostic significance in HCC at single-cell resolution has not been systematically investigated.…"
  9. 18049

    Image3_Dexamethasone and IFN-γ primed mesenchymal stem cells conditioned media immunomodulates aberrant NETosis in SLE via PGE2 and IDO.tif حسب Khushbu Priya (11863559)

    منشور في 2024
    "…Background<p>Systemic Lupus Erythematosus (SLE) is characterized by dysregulated immune responses, with neutrophil extracellular traps (NETs) playing a significant role. NETs are recognized by autoantibodies in SLE patients, exacerbating pathology. …"
  10. 18050

    Image2_Dexamethasone and IFN-γ primed mesenchymal stem cells conditioned media immunomodulates aberrant NETosis in SLE via PGE2 and IDO.tif حسب Khushbu Priya (11863559)

    منشور في 2024
    "…Background<p>Systemic Lupus Erythematosus (SLE) is characterized by dysregulated immune responses, with neutrophil extracellular traps (NETs) playing a significant role. NETs are recognized by autoantibodies in SLE patients, exacerbating pathology. …"
  11. 18051

    Supplementary Material for: Primary Vitreoretinal Lymphomas: A Diagnostic Challenge. Report of two recent cases with retinal biopsies and molecular investigations in Halifax, Nova... حسب figshare admin karger (2628495)

    منشور في 2025
    "…She had a further decline in her right eye vision with significant extension of the necrotizing retinitis into the macula and optic disc. …"
  12. 18052

    Supplementary file 1_Comparative effects of high-intensity interval training versus moderate-intensity continuous training on body composition and blood pressure in overweight adol... حسب Xilin Li (1913320)

    منشور في 2025
    "…The findings revealed that: (1) HIIT was superior in decreasing body fat percentage [MD = −0.74, 95% CI (−1.44, 0.04), Z = 2.74, P = 0,04]. …"
  13. 18053

    Table 5_Identification and validation for biomarkers associated with mitochondrial metabolism in chronic obstructive pulmonary disease.xlsx حسب Wenjun Wang (314231)

    منشور في 2025
    "…The mRNA and protein expression of APRT and LCAT were significantly decreased in COPD patients’ lung tissues.…"
  14. 18054

    Table 1_The advanced lung cancer inflammation index as a predictor of kidney stone risk in men: a cross-sectional analysis.docx حسب Yan Zhou (6523)

    منشور في 2025
    "…Background<p>Kidney stone incidence and recurrence are increasing, which poses significant health problems. The Advanced Lung Cancer Inflammation Index (ALI) combines body mass index (BMI), albumin, and neutrophil-to-lymphocyte ratio (NLR). …"
  15. 18055

    <b><i>Original data for "High risk of soil available silicon deficiency in bamboo forest: Insights from bamboo afforestation chronosequences in the karst region of southwest China"... حسب Kangning Yan (22751487)

    منشور في 2025
    "…Furthermore, aboveground Si content decreased significantly from leaves (10.54–21.45 g kg–1) to branches (3.81–5.61 g kg–1) and culms (1.07–1.98 g kg–1). …"
  16. 18056

    Data Sheet 1_Microbial dysbiosis in obstructive sleep apnea: a systematic review and meta-analysis.docx حسب Yang Guo (399435)

    منشور في 2025
    "…Beta diversity analysis indicated significant differences in the gut, respiratory and oral microbial community structure between individuals with OSA and those without in more than half of the included studies. …"
  17. 18057

    Data Sheet 1_Blue and red LEDs modulate polyphenol production in Precoce and Tardiva cultivars of Cichorium intybus L..pdf حسب Felicia Menicucci (7495508)

    منشور في 2025
    "…The polyphenolic composition of the two cultivars significantly changed depending on the type of LEDs used. …"
  18. 18058

    Data Sheet 6_Factors influencing, and associated with, physical activity patterns in dogs with osteoarthritis-associated pain.pdf حسب Christina Stevens (9737867)

    منشور في 2025
    "…</p>Results<p>At times of peak activity within a 24-h period, dogs with hindlimb OA pain, higher age, higher Clinical Metrology Instrument scores, higher joint pain, greater Body Condition Score and greater muscle atrophy all had decreased activity profiles. However, only age, hindlimb joint pain, and hindlimb muscle atrophy had statistically significant effects on physical activity.…"
  19. 18059

    Image 1_Antifungal mechanism and transcriptome analysis of Bacillomycin D-C16 against Fusarium oxysporum.tif حسب Fuxing Lin (7418234)

    منشور في 2025
    "…Furthermore, nearly all DEGs related to DNA replication were significantly suppressed. Biochemical assays confirmed these observations: Reduced activities of mitochondrial enzymes [malate dehydrogenase (MDH), isocitrate dehydrogenase (IDH), pyruvate dehydrogenase (PDH), and complexes I–V], decreased mitochondrial membrane potential, and diminished ATP content collectively indicated mitochondrial dysfunction. …"
  20. 18060

    Image 1_Club cell-derived brain-derived neurotrophic factor regulates murine airway mechanics and mucin production in response to IL-13 in a sex-dependent manner.jpeg حسب Amy Fagan (17678004)

    منشور في 2025
    "…No statistically significant differences were observed in pulmonary mechanics between male mice with or without conditional loss of epithelial cell Bdnf, although treatment effects of IL-13 were noted. …"