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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
point increase » unit increase (Expand Search)
main decrease » gain decreased (Expand Search), mean decrease (Expand Search), point decrease (Expand Search)
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18821
Data Sheet 1_Long-term effects of SGLT2 inhibitors on arrhythmias: a systematic review and meta-analysis.pdf
Published 2025“…The results of meta-analysis revealed that patients treated with SGLT2 inhibitors had a reduced risk of AF/AFL compared with placebo (RR 0.86; 95%CI, 0.77–0.95; I<sup>2</sup> = 0%; P = 0.003). There was no significant difference in the risk of AF/AFL between the high-dose SGLT2 inhibitors group and the low-dose SGLT2 inhibitors group (RR 0.78; 95%CI, 0.60–1.02; I<sup>2</sup> = 0%; P = 0.07), although a decreasing trend in the high-dose group was noted. …”
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18822
Image 3_Transcutaneous auricular vagus nerve stimulation alleviates inflammation-induced depression by modulating peripheral-central inflammatory cytokines and the NF-κB pathway in...
Published 2025“…</p>Results<p>Behavioral tests demonstrated that LPS-induced rats exhibited significant depressive-like behaviors, including reduced sucrose preference, decreased activity levels in the open field, and restricted exploratory behavior in the elevated plus maze. taVNS intervention significantly alleviated these depressive-like behaviors. …”
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18823
Table 1_Burn inhalation injury and intubation with dexamethasone-eluting endotracheal tubes modulate local microbiome and alter airway inflammation.xlsx
Published 2025“…Inflammatory markers IFN-γ, IL-4, and IL-1β were elevated in dexamethasone-ETT groups at 3 days, then decreased by 7 days. Macrophage markers CD86 and CD206 were significantly greater in dexamethasone groups compared to regular ETT groups at 7 days (p = 0.002 and p = 0.0213, respectively). …”
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18824
Table 2_The boundaries between PML and PML-IRIS: difficult to define, pathology may predict.docx
Published 2025“…</p>Results<p>Notably, 63.2% (12/19) of them had blood CD4+ T-cell counts < 200 cells/μl, and 36.8% (7/19) had ≥ 200 cells/μl. 52.9% (9/17) of the patients had elevated CSF protein, 5.3% (1/19) had decreased CSF glucose. Statistical analysis revealed significant correlations between mass effect and both blood CD4+ T-cell counts (P = 0.022) and CSF protein levels (P < 0.001). …”
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18825
Table 3_The boundaries between PML and PML-IRIS: difficult to define, pathology may predict.docx
Published 2025“…</p>Results<p>Notably, 63.2% (12/19) of them had blood CD4+ T-cell counts < 200 cells/μl, and 36.8% (7/19) had ≥ 200 cells/μl. 52.9% (9/17) of the patients had elevated CSF protein, 5.3% (1/19) had decreased CSF glucose. Statistical analysis revealed significant correlations between mass effect and both blood CD4+ T-cell counts (P = 0.022) and CSF protein levels (P < 0.001). …”
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18826
Table 3_Global, regional, and national epidemiology of Intracerebral Hemorrhage among women of childbearing age (1990–2021): incidence, mortality, DALYs, and risk factor analysis.x...
Published 2025“…Background and Objectives<p>Intracerebral Hemorrhage (ICH) is a serious cerebrovascular condition that poses a significant health risk to women of childbearing age (WCBA) globally. …”
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18827
Table 1_Global, regional, and national epidemiology of Intracerebral Hemorrhage among women of childbearing age (1990–2021): incidence, mortality, DALYs, and risk factor analysis.x...
Published 2025“…Background and Objectives<p>Intracerebral Hemorrhage (ICH) is a serious cerebrovascular condition that poses a significant health risk to women of childbearing age (WCBA) globally. …”
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18828
Data Sheet 1_Increased accrual of diverse patient populations in oncology phase I clinical trials at the University of Colorado Cancer Center.docx
Published 2025“…However, in the most common cancer type, colorectal cancer, higher ADI scores were associated with decreased median PFS and OS.</p>Conclusion<p>The interventions resulted in an increase in accrual of non-English speaking patients, however, there was not yet a significant change in overall race and ethnicity. …”
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18829
Propagation prediction of asymmetrically originated fractures by use of displacement discontinuity method
Published 2025“…As the fluid power law index decreases, the fluid viscosity is significantly reduced due to the effect of shear thinning, causing the asymmetrically originated fractures to propagate parallel to the direction of maximum principal stress. …”
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18830
Table 1_The expression regulation of recA gene and bacterial class 2 integron-associated genes induced by antibiotics.docx
Published 2025“…Continuous induction leads to sustained upregulation of these genes, which stabilizes or slightly decreases upon reaching a plateau. However, the capacity of different drugs to induce expression varies significantly. …”
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18831
Data Sheet 1_Global, regional, and national epidemiology of Intracerebral Hemorrhage among women of childbearing age (1990–2021): incidence, mortality, DALYs, and risk factor analy...
Published 2025“…Background and Objectives<p>Intracerebral Hemorrhage (ICH) is a serious cerebrovascular condition that poses a significant health risk to women of childbearing age (WCBA) globally. …”
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18832
Table 5_Nusinersen for children with type I spinal muscular atrophy: 4 years’ clinical experience in Turkish cohort.docx
Published 2025“…Ventilator and gastrostomy requirements decreased in the early treated cohorts. Adverse events were rare, with one discontinuation due to hydrocephalus. …”
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18833
Table 2_Bioelectrical impedance vector analysis in older adults: reference standards from a cross-sectional study.docx
Published 2025“…</p>Results<p>New reference values for older adults were established. Significant differences (p < 0.001) in R/H and phase angle were observed when older adults were grouped by age categories, while R/H, Xc/H, and phase angle showed significant differences among ALSM/H<sup>2</sup> tertiles. …”
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18834
Data Sheet 1_Global, regional, and national burden of interstitial lung disease in middle-aged and older adults from 1990 to 2021 with projections to 2050: a systematic analysis of...
Published 2025“…Joinpoint regression analysis revealed that while ASPR and ASIR increased from 1990 to 2010 but subsequently decreased from 2010 to 2021, conversely, ASDR and DALYs increased from 1990 to 2011 before declining after 2011, frontier analysis highlighted Canada, Ireland, the United States, Japan, and the United Kingdom as nations with significant improvement potential. …”
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18835
Table 1_Spatio-temporal patterns and determinants of persistent catastrophic health expenditure in China: evidence from the China Family Panel Studies.docx
Published 2025“…Background<p>The escalating out-of-pocket medical expenses pose a significant threat to the financial stability of households worldwide. …”
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18836
Supplementary file 1_Impacts of climate change on chronic respiratory health in Ethiopia: a systematic review and meta-analysis.docx
Published 2025“…Study design influenced prevalence estimates, with cross-sectional studies reporting higher rates (46%) than case–control studies (14%). Significant heterogeneity (I<sup>2</sup> = 99%, p < 0.001) was observed across studies.…”
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18837
Table 4_Isowighteone attenuates vascular calcification by targeting HSP90AA1-mediated PI3K-Akt pathway and suppressing osteogenic gene expression.xls
Published 2025“…(F. hispida, Moraceae), has demonstrated significant anti-inflammatory properties in prior studies. …”
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18838
Image 1_Impact of individualized tidal volume strategies on intraoperative lung protection and inflammatory markers in laparoscopic cholecystectomy: a randomized controlled trial.j...
Published 2025“…However, the increases in these inflammatory markers were significantly greater in Group C than in Group T (p < 0.05). …”
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18839
Table 2_Emerging cardiovascular toxicity associated with CDK4/6 inhibitors: real-world insights from the FDA adverse event reporting system.xlsx
Published 2025“…Disproportionality analysis revealed that Abemaciclib was significantly increased signal of venous thromboembolism (ROR = 2.57 [2.24-2.96]), whereas cardiac arrhythmia (ROR = 2.51 [2.13-2.96]) and torsade de pointes/QT prolongation (ROR = 5.7 [5-6.5]) were showed significantly disproportionate for ribociclib. …”
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18840
Supplementary Material for: Association of umbilical cord blood serotonin levels with neurodevelopmental outcomes
Published 2025“…Cord blood 5-HT was significantly associated with the Mullen Composite Score, and follow-up analyses revealed a significant association between cord blood 5-HT and fine motor skills. …”