VCC induces activation of neutrophils through TLR1/4/MyD88. حسب Shraddha Gandhi (21001590)

"…(C) Significant decrease in the VCC-mediated IL-6 production in the neutrophils from the TLR1^-/-, C3H/HeJ, and MyD88^-/- mice, as compared to those in neutrophils from the wild type (WT) mice. …"

Image 1_Double-lumen tubes verus single-lumen tube in patients undergoing minimally invasive cardiac surgery: a randomised, controlled clinical trial.pdf حسب Zhenzhong Wang (407028)

"…</p>Conclusions<p>Two-lung ventilation with single-lumen tube is easy to perform, significantly increases oxygenation, and decreases the incidence of postoperative complications and airway injuries. …"

DataSheet1_Synergistic effects of yeast and plant growth-promoting bacteria on Tobacco growth and soil-borne disease suppression: evidence from pot and field experiments.docx حسب Kai Teng (7038950)

"…Functional prediction further demonstrated a significant increase in the relative abundances of certain enzymes, including Alkaline phosphatase, 1-aminocyclopropane-1-carboxylate deaminase (ACC deaminase), and Peroxidase, as well as antimicrobial substances like Tetracycline, Isoquinoline alkaloid, and Phenylpropanoids, following inoculation with the fertilizer. …"

DataSheet2_Chitinase 1: a novel therapeutic target in metabolic dysfunction-associated steatohepatitis.docx حسب Jung Hoon Cha (19723588)

"…Although the population of F4/80⁺CD11b⁺ intrahepatic mononuclear phagocytes remained unchanged, their infiltration and activation (CHIT1⁺MerTK⁺) significantly decreased in OATD-01-treated mice, compared with that observed in vehicle-treated mice.…"

DataSheet1_Chitinase 1: a novel therapeutic target in metabolic dysfunction-associated steatohepatitis.zip حسب Jung Hoon Cha (19723588)

"…Although the population of F4/80⁺CD11b⁺ intrahepatic mononuclear phagocytes remained unchanged, their infiltration and activation (CHIT1⁺MerTK⁺) significantly decreased in OATD-01-treated mice, compared with that observed in vehicle-treated mice.…"

Data Sheet 1_Gram-positive enhancer matrix delivering FVpE via M cell targeting elicit protective mucosal and adaptive immune responses against Helicobacter pylori infection.doc حسب Furui Zhang (3181935)

"…Finally, H. pylori-infected mice treated with GEM-SAM-FVpE can significantly reduce the colonization of H. pylori in gastric tissue while also decreasing gastric mucosal damage.…"

DataSheet1_Causal effects of serum calcium, phosphate, and 25-hydroxyvitamin D on kidney function: a genetic correlation, pleiotropic analysis, and Mendelian randomization study.zi... حسب Yanjun Liang (4394089)

"…Similarly, serum P was associated with a decrease in eGFRcrea (beta −0.01, P-value 2.0E−04; beta −0.005, P-value 2.0E−03) and an increase in BUN (beta 0.02, P-value 3.0E−03; beta 0.02, P-value 7.5E−07). …"

Data Sheet 1_Modulation of TLR7, TYK2 and OAS1 expression during SARS-CoV-2 infection.pdf حسب Estíbaliz Alegría-Carrasco (22809476)

"…Gene expression was analyzed using Generalized Linear Mixed Models nested by patient. First, univariate analyses determined which variables were significantly associated with gene expression. …"

Altered spatial distribution of EPDCs in <i>Wt1</i>^Cre; <i>Sox9</i>^fl/fl; <i>R26</i>^mG hearts. حسب Andrew B. Harvey (21587431)

"…Chi-square analysis indicates a significant shift in spatial distribution (p < 0.0001). …"

MLN IFN- حسب Jessica Belmares-Ortega (21212731)

"…<p><b>γ</b><b>production is decreased in the absence of MyD88 and</b><b>αβ</b><b>T cells.…"

Image 1_Elevated thiamine level is associated with activating interaction between HIF-1α and SLC19A3 in experimental myopic guinea pigs.jpeg حسب Zhongyu Ma (12275357)

"…</p>Results<p>Compared with the normal control (NC) group, the LIM group guinea pigs showed a significant increase in axial length and decrease in refractive error, as well as a thinning of choroidal thickness and loosening of tissue structure. …"

Preeclamptic plasma disrupts endothelial function and promotes inflammation in endothelial cells: beneficial effects of glibenclamide and MCC950 in this scenario حسب Karoliny Nune Santos (21752603)

"…Both GB and MCC950 reduced NLRP3 inflammasome activation and its related effects in ECs exposed to PE plasma, including lowered IL-1β, caspase-1, modulated adhesion molecules expression, as well as decreased ROS and cytotoxicity. GB increased NO and restored VE-cadherin expression, while MCC950 enhanced antioxidant capacity. …"

Algorithms for designing continuous curricula A: Decision tree showing the continuous version of ADP which includes actions that “grow” and “shrink” the increments between continuo... حسب William L. Tong (22238845)

"…Continuous ADP first decreases increment size and smoothly increases the difficulty level while balancing reinforcement and extinction.…"

TITAN analyses. حسب Erik W. Ertsgaard (20521628)

"…<p>Taxa significantly associated with increasing or decreasing MAP in our TITAN. …"

Data Sheet 1_Disease spectrum of patients with hospital-acquired multidrug-resistant organism infections in the intensive care unit: a retrospective study.doc حسب Xiaowu Wang (167537)

"…</p>Conclusion<p>Our data show the mortality rate of hospital-acquired MDRO infections decreased during COVID-19 and increased after restrictions eased. …"

Data Sheet 1_Impact of self-reported SARS-CoV-2 antibody positivity on cardiac structure and function: findings from UK Biobank CMR cohort.docx حسب Chang Liu (35901)

"…Over an average follow-up period of 110 days, significant decreases in CO and CI were observed in the paired participants. …"

Table 1_Dietary quercetagetin attenuates H2O2-induced oxidative damage and preserves meat quality in broilers by modulating redox status and Nrf2/ferroptosis signaling pathway.docx حسب Wenyue Hu (799025)

"…Meanwhile, the addition of QG to the diet increased the mRNA expressions of Nrf2 and TFR1, showing no significant difference from those of the control group. …"

Supplementary file 1_Association between changes in corrected anion gap and mortality among critically ill patients during ICU stay: a multicenter observational study.doc حسب Yanli Hou (6561536)

"…When analyzed categorically, the ΔcAG still exhibited a significant risk gradient across quartiles.</p>Conclusion<p>Further elevated cAG after ICU admission demonstrates a robust association with an increased mortality risk in critically ill patients. …"

Reduced expression of MYBPC3 mRNA and cMyBP-C protein in the proband. حسب Yuanyuan Zhang (101797)

"…<p>(A) RT-qPCR analysis showing significantly decreased MYBPC3 mRNA levels in cardiac sample from the proband compared to control subjects. …"

FLEXI interactions with RNA-binding proteins. حسب Jun Yao (9646)

"…RNA-binding sites: I, within introns corresponding to FLEXIs; SS-I and SS-E, bimodally enriched across the 5’- and 3’ splice sites in unspliced pre-mRNAs with the midpoints in the intron or flanking exon (SS-I and SS-E, respectively; Figs <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1011416#pgen.1011416.g004" target="_blank">4A</a> and <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1011416#pgen.1011416.s011" target="_blank">S11</a>). mRNA levels, RBPs whose knockdown resulted in significant difference in mRNA levels (increased or decreased, DESeq2 |LFC|≥1, adjusted p≤0.05) from host gene of FLEXIs with a binding site for that RBP compared to those genes whose transcripts lacked a binding site for the same RBPs based on ENCODE RBP-knockdown datasets (p≤0.05 calculated by Fisher’s exact test; <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1011416#pgen.1011416.s013" target="_blank">S13 Fig</a>). …"