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Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
Published 2014“…The increase in apoptosis in response to treatment was also apparent in the increase in BAX and the decrease in Bcl-2 levels as well as the proteolytic cleavage of both caspase-3 and PARP as revealed by Western blot. …”
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Phospholipase C negatively regulates Rac/Cdc42 activation in antigen-stimulated mast cells
Published 2007“…The inhibition of phospholipase C (PLC)c causes a twofold increase in Rac and Cdc42 activation that coincides with a dramatic production of atypical filopodialike structures. …”
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Lower limb EMG activation during reduced gravity running on an incline. Speed matters more than hills irrespective of indicated bodyweight
Published 2021“…Increasing running speed was associated with the largest change in activity, with smaller effects for increasing bodyweight and inclination. …”
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Chemical characterization and cytotoxic activity evaluation of Lebanese propolis
Published 2017“…Interestingly, the decrease in cell viability was accompanied by a significant increase in p53 protein expression levels and PARP cleavage. …”
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Measured enthalpies of adsorption of boron-doped activated carbons
Published 2012“…There is significant interest in the properties of boron-doped activated carbons for their potential to improve hydrogen storage. ootnotetextMultiply Surface-Functionalized Nanoporous Carbon for Vehicular Hydrogen Storage, P. …”
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Transglutaminase inhibition protects against oxidative stress-induced neuronal death downstream of pathological ERK activation
Published 2012“…These small molecules inhibit increases in neuronal transamidating activity induced by oxidative stress; they also protect neurons downstream of pathological ERK activation when added well after the onset of the death stimulus. …”
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Activism, Change and Sectarianism in the Free Patriotic Movement in Lebanon
Published 2020“…The book also reveals the formation of intricate units and communication channels to mobilize activism and increase commitment to the movement’s cause. …”
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Indomethacin as a Rescue Therapy for Patent Ductus Arteriosus in Extremely Premature Infants after Failed Ibuprofen Treatment
Published 2023“…While most PDAs close after one 3-day course of either medicine, a repeat course may be necessary before considering surgical ligation for those who remain with hsPDAs. In our practice, we administer one or two courses of ibuprofen followed by a single course of indomethacin if the PDA has not shown closure or decrease in size on the echocardiogram (echo) exam. …”
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Morphological changes in amblyopic eyes in choriocapillaris and Sattler’s layer in comparison to healthy eyes, and in retinal nerve fiber layer in comparison to fellow eyes through...
Published 2021“…Results The method of measuring reflectivity is good to excellent reliability for all regions of interest except the fourth. The mean reflectivity of the choriocapillaris and Sattler’s layer in amblyopic eyes were significantly lower than in healthy eyes (p = 0.003 and p = 0.008 respectively). …”
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A novel inhibitor of signal transducers and activators of transcription 3 activation is efficacious against established central nervous system melanoma and inhibits regulatory T ce...
Published 2008“…Although WP1066 did not induce immunologic memory or enhance humoral responses to EGFRvIII, this compound reduced the production of immunosuppressive cytokines and chemokines (transforming growth factor-β, RANTES, MCP-1, vascular endothelial growth factor), markedly inhibited natural and inducible Treg proliferation, and significantly increased cytotoxic immune responses of T cells. …”
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Growth hormone treatment modulates active ghrelin levels in rats
Published 2014“…Genotropin treatment caused a dose dependent decrease in active ghrelin concentration in stomach, kidney and pancreas with a concomitant increase in plasma, and reaching significance at 20 and 100 µg/rat/day doses. …”
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A green route to the synthesis of highly porous activated carbon from walnut shells for mercury removal
Published 2024“…<p dir="ltr">Activated carbon with a high surface area was synthesized using walnut shells with the objective of removing mercury ions. …”
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Role of Active Morphing in the Aerodynamic Performance of Flapping Wings in Formation Flight
Published 2021“…Birds have the ability to actively morph their wings during the flapping cycle. …”
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In-Vehicle Performance Validation of the Semi-Active Hybrid Energy Storage System
Published 2015“…Recent research has focused on a variety of HESS circuit design topologies [1]-[4] and power management and control [5]-[6]. The passive, semi-active, and active HESS configurations have gained significant attention. …”
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A novel inhibitor of STAT3 activation is efficacious against established central nervous system melanoma and inhibits regulatory T cells
Published 2008“…Although WP1066 did not induce immunological memory or enhance humoral responses to EGFRvIII, this compound reduced the production of immunosuppressive cytokines and chemokines (TGF-β, RANTES, MCP-1, VEGF), markedly inhibited natural and inducible Treg proliferation, and significantly increased cytotoxic immune responses of T cells. …”
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Beauvericin potentiates the activity of pesticides by neutralizing the ATP-binding cassette transporters in arthropods
Published 2022“…Consequently, resistant pests reduce the yield of agricultural production, causing significant economic losses and reducing food security. …”
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Acoustically activated release of estrone-targeted liposomes used for breast cancer treatment
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The Environmental Barriers to Active School Travel Among Private School Students in Dubai
Published 2021“…Childhood obesity rates are increasing, partly caused by a deficiency of physical activity (PA). …”
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