Showing 1,601 - 1,620 results of 21,964 for search '(( significant ((negative decrease) OR (negative breast)) ) OR ( significant decrease decrease ))', query time: 0.44s Refine Results
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    Image_1_RETRACTED: Eupalinolide J Suppresses the Growth of Triple-Negative Breast Cancer Cells via Targeting STAT3 Signaling Pathway.pdf by Chenghua Lou (7403240)

    Published 2025
    “…<p>Persistent activation of STAT3 plays an important role in the development of triple-negative breast cancer (TNBC), and suppression of STAT3 is considered as a novel approach for cancer therapy. …”
  5. 1605

    Data Sheet 1_Prognostic value of left atrial strain in significant aortic valve disease: a systematic review and meta-analysis.pdf by Na Chen (153323)

    Published 2025
    “…Background<p>Previous studies on aortic valve disease have mainly focused on the left ventricle, but increasing evidence suggests that left atrial strain also has prognostic value in significant aortic valve disease.</p>Objective<p>To systematically evaluate the prognostic value of left atrial strain in significant aortic valve disease.…”
  6. 1606

    Discovery of Diaryl Piperidone-Sulfonamide as a Novel Dual-Target Inhibitor of STAT3/CAIX Inducing Ferroptosis in Triple-Negative Breast Cancer Cells by Lei Chen (54296)

    Published 2025
    “…A series of diaryl piperidone-sulfonamide derivatives were designed as dual inhibitors of STAT3/CAIX and ferroptosis inducers for triple-negative breast cancer (TNBC). The representative compound <b>7m</b> demonstrated significant antitumor effects against the MDA-MB-231 cell line both <i>in vitro</i> and <i>in vivo</i>. …”
  7. 1607

    Discovery of Diaryl Piperidone-Sulfonamide as a Novel Dual-Target Inhibitor of STAT3/CAIX Inducing Ferroptosis in Triple-Negative Breast Cancer Cells by Lei Chen (54296)

    Published 2025
    “…A series of diaryl piperidone-sulfonamide derivatives were designed as dual inhibitors of STAT3/CAIX and ferroptosis inducers for triple-negative breast cancer (TNBC). The representative compound <b>7m</b> demonstrated significant antitumor effects against the MDA-MB-231 cell line both <i>in vitro</i> and <i>in vivo</i>. …”
  8. 1608

    Discovery of Diaryl Piperidone-Sulfonamide as a Novel Dual-Target Inhibitor of STAT3/CAIX Inducing Ferroptosis in Triple-Negative Breast Cancer Cells by Lei Chen (54296)

    Published 2025
    “…A series of diaryl piperidone-sulfonamide derivatives were designed as dual inhibitors of STAT3/CAIX and ferroptosis inducers for triple-negative breast cancer (TNBC). The representative compound <b>7m</b> demonstrated significant antitumor effects against the MDA-MB-231 cell line both <i>in vitro</i> and <i>in vivo</i>. …”
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    Table 1_A novel prognostic signature identifies MFAP4 as a tumor suppressor linking the tumor microenvironment to PI3K/AKT signaling in triple-negative breast cancer.docx by Xiaoqin Yu (3918377)

    Published 2025
    “…Background<p>Triple-negative breast cancer (TNBC) remains a clinical challenge due to its aggressiveness and limited therapeutic options. …”
  14. 1614

    Table 2_A novel prognostic signature identifies MFAP4 as a tumor suppressor linking the tumor microenvironment to PI3K/AKT signaling in triple-negative breast cancer.xlsx by Xiaoqin Yu (3918377)

    Published 2025
    “…Background<p>Triple-negative breast cancer (TNBC) remains a clinical challenge due to its aggressiveness and limited therapeutic options. …”
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    Data Sheet 1_A novel prognostic signature identifies MFAP4 as a tumor suppressor linking the tumor microenvironment to PI3K/AKT signaling in triple-negative breast cancer.pdf by Xiaoqin Yu (3918377)

    Published 2025
    “…Background<p>Triple-negative breast cancer (TNBC) remains a clinical challenge due to its aggressiveness and limited therapeutic options. …”
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    Effect of NPRC KO on renal function. by Liming Wang (114648)

    Published 2025
    “…KO of NPRC decreased cystatin C levels in Gq mice but the difference was not statistically significant.…”
  17. 1617

    Effect of NPRC KO on podocyte proteins. by Liming Wang (114648)

    Published 2025
    “…<p>(<b>7</b>A & <b>7</b>B) Expression of nephrin and podocin mRNAs were significantly decreased in glomerular preparations from Gq mice compared to controls and expression of both podocyte proteins were preserved by podocyte specific KO of NPRC. (7C & 7D) The pattern of nephrin protein expression was similar to the mRNA results, but the differences were not statistically significant.…”
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    Effect of podocyte specific NPRC KO on systemic BP and albuminuria. by Liming Wang (114648)

    Published 2025
    “…<p>(<b>4</b>A) Systolic BP was similarly decreased in both groups of Gq mice compared to controls, but this difference was not statistically significant. …”
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    Effect of NPRC KO on fibrotic markers. by Liming Wang (114648)

    Published 2025
    “…Podocyte specific KO of NPRC decreased expression of both fibronectin and Col4 alpha-1, which was statistically significant for Col4 alpha-1. …”