يعرض 18,621 - 18,640 نتائج من 21,342 نتيجة بحث عن '(( significant ((new decrease) OR (a decrease)) ) OR ( significant decrease decrease ))', وقت الاستعلام: 0.55s تنقيح النتائج
  1. 18621

    DESeq output data for all comparisons. حسب Hilary T. Brewis (11798006)

    منشور في 2025
    "…Furthermore, as H2A.Z mutants only display significant growth defects in genotoxic stress conditions, a more substantive role for H2A.Z in gene expression may only be uncovered after exposure to cellular stress. …"
  2. 18622

    <b>Astragalus polysaccharide and </b><b><i>Clostridium butyricum</i></b><b> synergistically inhibit bone loss in mice with humanized intestinal flora</b> حسب Hongtao Zhang (20774453)

    منشور في 2025
    "…</p><p dir="ltr">This finding not only provides a new intervention strategy for astronauts' bone health in space, but also provides a theoretical basis for improving bone metabolism by regulating the gut microbiota. …"
  3. 18623

    Table 1_Optimization of drying parameters and texture properties of winter jujube slices by radio frequency combined with hot air.xlsx حسب Yang Li (7082)

    منشور في 2025
    "…The research results provide a new drying combination mechanism and process optimization scheme for improving the drying technology of winter jujube slices in industrial production.…"
  4. 18624

    Table 1_High-calcium milk improves osteoporosis in postmenopausal women by regulating intestinal flora and steroid hormone biosynthesis.docx حسب Yanyan Zhao (211551)

    منشور في 2025
    "…</p>Results<p>A one-year randomized controlled trial showed that the high-calcium milk group significantly increased lumbar spine bone mineral density (L1-4 BMD), slowed bone loss in the left hip and femoral neck, elevated serum phosphorus and 25-hydroxyvitamin D levels, and modulated the bone formation marker procollagen type I N-terminal propeptide compared with the regular milk group at 6 months. 16S ribosomal ribonucleic acid sequencing showed that high-calcium milk significantly altered the β-diversity of the intestinal flora, increasing the abundance of beneficial bacteria such as Bacteroides, Oscillibacter, and Subdoligranulum, while decreasing the abundance of Firmicutes and Weissella at 12 months. …"
  5. 18625

    Image 1_Population pharmacokinetics of polymyxin B in critically ill patients with carbapenem-resistant organisms infections: insights from steady-state trough and peak plasma conc... حسب Jun Yang (2084)

    منشور في 2025
    "…A one-compartment model was developed, with creatinine clearance (CrCL) and platelet count (PLT) identified as significant covariates influencing PK parameters. …"
  6. 18626

    Dynamic changes in mRNA stability. حسب Shiqi Luo (3829597)

    منشور في 2025
    "…A significant increase of CSC values for AU3 codon was observed in LPS 6 hours, compared with LPS 0 hour, indicating that AU3 codon further stabilizes mRNAs after 6 hours of LPS treatment. …"
  7. 18627

    Table 1_Long-term oyster shell powder applications increase crop yields and control soil acidity and cadmium in red soil drylands.docx حسب Hao Li (31608)

    منشور في 2025
    "…Meanwhile, available Cd content was extracted using 0.1 M CaCl<sub>2</sub> and measured with a flame atomic absorption spectrophotometer. While all treatments showed an annual decline in peanut yield from 2013 to 2018, but oyster shell applications significantly reduced the rate of crop yield decline. …"
  8. 18628

    Interplay of <i>Mycobacterium abscessus</i> and <i>Pseudomonas aeruginosa</i> in experimental models of coinfection: Biofilm dynamics and host immune response حسب Víctor Campo-Pérez (21267009)

    منشور في 2025
    "…Coinfections in bronchial epithelial cells significantly decreased cell viability, whereas in <i>G. mellonella</i>, coinfections induced lower survival rates than individual infections. …"
  9. 18629

    Image 1_Association of estimated glucose disposal rate with chronic kidney disease: comparative analysis against traditional insulin resistance indices.jpeg حسب Yuanxin Liu (6307949)

    منشور في 2025
    "…Background<p>Chronic kidney disease (CKD) is a widespread condition, marked by significant morbidity and mortality rates, particularly in individuals with comorbidities such as diabetes and hypertension. …"
  10. 18630

    Data Sheet 1_Risk factors of low bone mass in young patients with transfusion-dependent beta-thalassemia.docx حسب Wei Zhang (405)

    منشور في 2025
    "…Without height-adjusted BMD correction, the overall prevalence was 31.6% (33.4% in the 5-19-year subgroup), which significantly decreased to 15.8% in the 5-19-year subgroup after height-adjusted correction, highlighting that traditional BMD assessments may overestimate risk due to unaccounted short stature. …"
  11. 18631

    Data Sheet 1_Global burden and trend of stroke attributable to metabolic risks among young adults (20–39 years old) from 1990 to 2021.docx حسب Qingguo Liu (9620123)

    منشور في 2025
    "…</p>Conclusions<p>Despite a decline in ASDR, the absolute burden of stroke attributable to metabolic risks among young adults has increased globally, with significant regional and national disparities. …"
  12. 18632

    Table 4_Antifungal mechanism and transcriptome analysis of Bacillomycin D-C16 against Fusarium oxysporum.xlsx حسب Fuxing Lin (7418234)

    منشور في 2025
    "…Furthermore, nearly all DEGs related to DNA replication were significantly suppressed. Biochemical assays confirmed these observations: Reduced activities of mitochondrial enzymes [malate dehydrogenase (MDH), isocitrate dehydrogenase (IDH), pyruvate dehydrogenase (PDH), and complexes I–V], decreased mitochondrial membrane potential, and diminished ATP content collectively indicated mitochondrial dysfunction. …"
  13. 18633

    Supplementary file 1_Exploration of the renoprotective effect of Yi-Shen-Hua-Shi granules on db/db mice and the mechanism of podocyte apoptosis based on the GRP78/CHOP signaling pa... حسب Yanmo Cai (22235563)

    منشور في 2025
    "…</p>Results<p>YSHS significantly improved the general status of db/db mice, with a significant reduction in body mass, renal function indices, total cholesterol, triglycerides, and low-density lipoprotein. …"
  14. 18634

    Data Sheet 1_The role of oxidative stress in modulating mortality risk across the hypertension control cascade.docx حسب Weihao Liu (4472227)

    منشور في 2025
    "…Q1, HR: 0.82; 95% CI: 0.66–0.87; P < 0.001). A significant interaction was observed between OBS and hypertension control status (P for interaction = 0.017 and 0.026), corroborated by sensitivity analyses (P for interaction = 0.025). …"
  15. 18635

    Table 1_Antifungal mechanism and transcriptome analysis of Bacillomycin D-C16 against Fusarium oxysporum.docx حسب Fuxing Lin (7418234)

    منشور في 2025
    "…Furthermore, nearly all DEGs related to DNA replication were significantly suppressed. Biochemical assays confirmed these observations: Reduced activities of mitochondrial enzymes [malate dehydrogenase (MDH), isocitrate dehydrogenase (IDH), pyruvate dehydrogenase (PDH), and complexes I–V], decreased mitochondrial membrane potential, and diminished ATP content collectively indicated mitochondrial dysfunction. …"
  16. 18636

    Table 2_The global burden of pediatric infective endocarditis (5–14 years): epidemiological patterns from 1990 to 2021 and projected trajectories.pdf حسب Ying Xiao (6517)

    منشور في 2025
    "…Background<p>Pediatric infective endocarditis (IE) remains a rare but life-threatening condition, with substantial morbidity and mortality among children worldwide. …"
  17. 18637

    DataSheet1_Effects of inulin-type oligosaccharides (JSO) from Cichorium intybus L. on behavioral deficits induced by chronic restraint stress in mice and associated molecular alter... حسب Caihong Yao (15344128)

    منشور في 2024
    "…<p>Depression and anxiety are serious psychiatric disorders with significant physical and mental health impacts, necessitating the development of safe and effective treatments. …"
  18. 18638

    Data Sheet 1_Altered immune cell profiles in blood of mature/peripheral T-cell leukemia/lymphoma patients: an EuroFlow study.docx حسب F. Javier Morán-Plata (18986483)

    منشور في 2025
    "…Further dissection of the normal T-cell compartment showed a significant reduction of the earliest T-cell maturation compartments (N/CM) in T-PLL and SS/MF, whereas T-cells remained within normal ranges in T-LGLL, with only a minor reduction of N/CM T-cells.…"
  19. 18639

    Image 2_Antifungal mechanism and transcriptome analysis of Bacillomycin D-C16 against Fusarium oxysporum.tif حسب Fuxing Lin (7418234)

    منشور في 2025
    "…Furthermore, nearly all DEGs related to DNA replication were significantly suppressed. Biochemical assays confirmed these observations: Reduced activities of mitochondrial enzymes [malate dehydrogenase (MDH), isocitrate dehydrogenase (IDH), pyruvate dehydrogenase (PDH), and complexes I–V], decreased mitochondrial membrane potential, and diminished ATP content collectively indicated mitochondrial dysfunction. …"
  20. 18640

    Table 3_Antifungal mechanism and transcriptome analysis of Bacillomycin D-C16 against Fusarium oxysporum.xlsx حسب Fuxing Lin (7418234)

    منشور في 2025
    "…Furthermore, nearly all DEGs related to DNA replication were significantly suppressed. Biochemical assays confirmed these observations: Reduced activities of mitochondrial enzymes [malate dehydrogenase (MDH), isocitrate dehydrogenase (IDH), pyruvate dehydrogenase (PDH), and complexes I–V], decreased mitochondrial membrane potential, and diminished ATP content collectively indicated mitochondrial dysfunction. …"