Image 1_Low hydrostatic pressure promotes functional homeostasis of nucleus pulposus cells through the TRPV4/CRT/FA complex axis.tiff حسب Junxian Hu (8158044)

"…In this study, we observed that under low hydrostatic pressure, TRPV4 activation and subsequent calcium influx led to an increase in CRT synthesis and a significant rise in its cytosolic expression. …"

Healthy control group HR and CBF changes. حسب Liuchuang Wei (19273099)

"…Computational results revealed that hypovolemia reduces cerebral blood flow by approximately 100 mL/min due to a 30% decrease in blood volume, while vascular dysfunction—marked by a 50–100% increase in arterial stiffness—further diminishes cardiac output and cerebral perfusion. …"

Data Sheet 1_Low hydrostatic pressure promotes functional homeostasis of nucleus pulposus cells through the TRPV4/CRT/FA complex axis.zip حسب Junxian Hu (8158044)

"…In this study, we observed that under low hydrostatic pressure, TRPV4 activation and subsequent calcium influx led to an increase in CRT synthesis and a significant rise in its cytosolic expression. …"

List of abbreviations used in this paper. حسب Liuchuang Wei (19273099)

"…Computational results revealed that hypovolemia reduces cerebral blood flow by approximately 100 mL/min due to a 30% decrease in blood volume, while vascular dysfunction—marked by a 50–100% increase in arterial stiffness—further diminishes cardiac output and cerebral perfusion. …"

Estimation of the CO and CBF. حسب Liuchuang Wei (19273099)

"…Computational results revealed that hypovolemia reduces cerebral blood flow by approximately 100 mL/min due to a 30% decrease in blood volume, while vascular dysfunction—marked by a 50–100% increase in arterial stiffness—further diminishes cardiac output and cerebral perfusion. …"

Image 6_Integrative RNA-seq and CLIP-seq analysis reveals hnRNP-F regulation of TNFα/NFκB signaling in high-glucose conditions.tif حسب Lan Wang (85307)

"…Conversely, this upregulation led to a significant increase in alternative splicing events of genes implicated in DKD, such as hnRNPA2B1, OSML, UGT2B7, TRIP6, and IRF3. …"

Table 3_Integrative RNA-seq and CLIP-seq analysis reveals hnRNP-F regulation of TNFα/NFκB signaling in high-glucose conditions.xlsx حسب Lan Wang (85307)

"…Conversely, this upregulation led to a significant increase in alternative splicing events of genes implicated in DKD, such as hnRNPA2B1, OSML, UGT2B7, TRIP6, and IRF3. …"

Image 3_Integrative RNA-seq and CLIP-seq analysis reveals hnRNP-F regulation of TNFα/NFκB signaling in high-glucose conditions.tif حسب Lan Wang (85307)

"…Conversely, this upregulation led to a significant increase in alternative splicing events of genes implicated in DKD, such as hnRNPA2B1, OSML, UGT2B7, TRIP6, and IRF3. …"

Table 7_Integrative RNA-seq and CLIP-seq analysis reveals hnRNP-F regulation of TNFα/NFκB signaling in high-glucose conditions.xls حسب Lan Wang (85307)

"…Conversely, this upregulation led to a significant increase in alternative splicing events of genes implicated in DKD, such as hnRNPA2B1, OSML, UGT2B7, TRIP6, and IRF3. …"

Image 2_Integrative RNA-seq and CLIP-seq analysis reveals hnRNP-F regulation of TNFα/NFκB signaling in high-glucose conditions.tif حسب Lan Wang (85307)

"…Conversely, this upregulation led to a significant increase in alternative splicing events of genes implicated in DKD, such as hnRNPA2B1, OSML, UGT2B7, TRIP6, and IRF3. …"

Image 1_Integrative RNA-seq and CLIP-seq analysis reveals hnRNP-F regulation of TNFα/NFκB signaling in high-glucose conditions.tif حسب Lan Wang (85307)

"…Conversely, this upregulation led to a significant increase in alternative splicing events of genes implicated in DKD, such as hnRNPA2B1, OSML, UGT2B7, TRIP6, and IRF3. …"

Table 8_Integrative RNA-seq and CLIP-seq analysis reveals hnRNP-F regulation of TNFα/NFκB signaling in high-glucose conditions.xls حسب Lan Wang (85307)

"…Conversely, this upregulation led to a significant increase in alternative splicing events of genes implicated in DKD, such as hnRNPA2B1, OSML, UGT2B7, TRIP6, and IRF3. …"

Table 9_Integrative RNA-seq and CLIP-seq analysis reveals hnRNP-F regulation of TNFα/NFκB signaling in high-glucose conditions.xls حسب Lan Wang (85307)

"…Conversely, this upregulation led to a significant increase in alternative splicing events of genes implicated in DKD, such as hnRNPA2B1, OSML, UGT2B7, TRIP6, and IRF3. …"

Image 7_Integrative RNA-seq and CLIP-seq analysis reveals hnRNP-F regulation of TNFα/NFκB signaling in high-glucose conditions.tif حسب Lan Wang (85307)

"…Conversely, this upregulation led to a significant increase in alternative splicing events of genes implicated in DKD, such as hnRNPA2B1, OSML, UGT2B7, TRIP6, and IRF3. …"

Table 5_Integrative RNA-seq and CLIP-seq analysis reveals hnRNP-F regulation of TNFα/NFκB signaling in high-glucose conditions.xlsx حسب Lan Wang (85307)

"…Conversely, this upregulation led to a significant increase in alternative splicing events of genes implicated in DKD, such as hnRNPA2B1, OSML, UGT2B7, TRIP6, and IRF3. …"

Image 4_Integrative RNA-seq and CLIP-seq analysis reveals hnRNP-F regulation of TNFα/NFκB signaling in high-glucose conditions.tif حسب Lan Wang (85307)

"…Conversely, this upregulation led to a significant increase in alternative splicing events of genes implicated in DKD, such as hnRNPA2B1, OSML, UGT2B7, TRIP6, and IRF3. …"

Image 5_Integrative RNA-seq and CLIP-seq analysis reveals hnRNP-F regulation of TNFα/NFκB signaling in high-glucose conditions.tif حسب Lan Wang (85307)

"…Conversely, this upregulation led to a significant increase in alternative splicing events of genes implicated in DKD, such as hnRNPA2B1, OSML, UGT2B7, TRIP6, and IRF3. …"

Table 1_Integrative RNA-seq and CLIP-seq analysis reveals hnRNP-F regulation of TNFα/NFκB signaling in high-glucose conditions.xls حسب Lan Wang (85307)

"…Conversely, this upregulation led to a significant increase in alternative splicing events of genes implicated in DKD, such as hnRNPA2B1, OSML, UGT2B7, TRIP6, and IRF3. …"

Table 6_Integrative RNA-seq and CLIP-seq analysis reveals hnRNP-F regulation of TNFα/NFκB signaling in high-glucose conditions.xls حسب Lan Wang (85307)

"…Conversely, this upregulation led to a significant increase in alternative splicing events of genes implicated in DKD, such as hnRNPA2B1, OSML, UGT2B7, TRIP6, and IRF3. …"

Table 2_Integrative RNA-seq and CLIP-seq analysis reveals hnRNP-F regulation of TNFα/NFκB signaling in high-glucose conditions.docx حسب Lan Wang (85307)

"…Conversely, this upregulation led to a significant increase in alternative splicing events of genes implicated in DKD, such as hnRNPA2B1, OSML, UGT2B7, TRIP6, and IRF3. …"