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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
nn decrease » _ decrease (Expand Search), a decrease (Expand Search), mean decrease (Expand Search)
we decrease » _ decrease (Expand Search), a decrease (Expand Search), mean decrease (Expand Search)
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18541
Development of immediate release tablet formulations of lornoxicam with hot melt extrusion-based three-dimensional printing technology
Published 2025“…Tablet erosion increased as the infill density decreased, and an immediate release profile was reached with tablets having 25% infill density. …”
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18542
Data Sheet 2_Lathyrol inhibits the proliferation of Renca cells by altering expression of TGF-β/Smad pathway components and subsequently affecting the cell cycle.xlsx
Published 2025“…The TGF-β/Smad signaling pathway plays a significant role in the development and progression of RCC.…”
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18543
Data Sheet 1_Do you speak cat? Assessing the impact of a training video on human recognition of cat emotions and behaviours during play interactions.pdf
Published 2025“…Training had a small but significant positive impact on overall performance but paradoxically significantly decreased subtle negative behaviour recognition. …”
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18544
Data Sheet 4_GLP-1 and glucagon receptor dual agonism ameliorates kidney allograft fibrosis by improving lipid metabolism.pdf
Published 2025“…Moreover, TB001 treatment decreased the body weight and serum total cholesterol, LDL-cholesterol, and TNF-α levels in transplant recipients, indicating metabolic improvements. …”
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18545
Image 1_MicroRNA-27b alleviates septic cardiomyopathy by targeting the Mff/MAVS axis.tif
Published 2025“…</p>Results<p>Bioinformatics analysis revealed significant downregulation of miR-27b in SCM cardiac tissues (log2FC=-3.9, P<0.001). …”
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18546
Table 2_GLP-1 and glucagon receptor dual agonism ameliorates kidney allograft fibrosis by improving lipid metabolism.docx
Published 2025“…Moreover, TB001 treatment decreased the body weight and serum total cholesterol, LDL-cholesterol, and TNF-α levels in transplant recipients, indicating metabolic improvements. …”
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18547
Table 1_Impact of in-hospital COVID-19 quarantine policy changes on quality of acute stroke care: a single center experience.docx
Published 2025“…However, after accounting for potential confounders, a significant delay in DIT was found to be associated with the in-hospital COVID-19 quarantine policy.…”
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18548
Image 1_Mitochondrial metabolism is rapidly re-activated in mature neutrophils to support stimulation-induced response.tif
Published 2025“…Treatment with these inhibitors also impacts neutrophil redox status, migration, and apoptosis without significantly changing overall bioenergetics.</p>Conclusions<p>Together, these results demonstrate that mitochondrial metabolism is dynamically remodeled and plays a significant role in neutrophils. …”
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18549
Table 2_Inequalities and age-period-cohort effects of global and regional burden for interstitial lung disease and pulmonary sarcoidosis: based on Global Burden of Disease study 20...
Published 2025“…Background<p>Interstitial lung disease (ILD) and pulmonary sarcoidosis pose significant disease burdens on a global scale.</p>Methods<p>The underlying data was derived from the Global Burden of Disease (GBD) 2021 database. …”
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18550
miR-155 directly targets the 3′UTR of TRAF3 and STAT1.
Published 2025“…<b>(F)</b> TRAF3 and STAT1 expression is decreased during the late phase of ALV-J infection. …”
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18551
Characterization of Behaviors During Food Consumption Under Novelty and Threat Learning in Male and Female Rats (MK Thesis)
Published 2025“…During extinction, all subjects decreased freezing behavior and increased mobility and neutral behaviors, indicating extinction learning. …”
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18552
Supplementary file 3_Impacts of Bacillus-based biotics and an enzyme cocktail on growth performance, immunity, and gut pathogenic microorganisms of nursery pigs under commercial co...
Published 2025“…</p>Results<p>The growth performance did not show significant differences according to the feed additives. …”
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18553
Table 1_Role of miR-144-5p in modulating lipid metabolism and potentially alleviating obesity via the PGC-1α/AMPK pathway.docx
Published 2025“…</p>Results<p>The treatment significantly reduced diet-induced adiposity and decreased inflammatory responses. …”
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18554
Table 9_Cardiac energy metabolic disorder and gut microbiota imbalance: a study on the therapeutic potential of Shenfu Injection in rats with heart failure.csv
Published 2025“…</p>Results<p>Myocardial energy metabolism in HF rats was disordered, characterized by reduced fatty acid oxidation, enhanced anaerobic glycolysis of glucose, mitochondrial damage, and decreased ATP content; The gut microbiota of HF rats was imbalanced, with a reduction in beneficial bacteria, an increase in conditional pathogenic bacteria, and impaired intestinal barrier function; Both Shenfu Injection and trimetazidine improved myocardial energy metabolism and cardiac function, but Shenfu Injection was more significant in regulating gut microbiota and improving intestinal health; The production of SCFAs from the gut microbiota of HF rats increased, which may be closely related to myocardial energy metabolism; SCFAs-producing bacteria Akkermansia and Blautia played a key role in the development of HF, and their abundance was positively correlated with SCFAs content.…”
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18555
Dexmedetomidine improves septic acute kidney injury by inhibiting inflammation and oxidative stress through the activation of the Pink1/Park2 autophagy pathway
Published 2025“…Notably, all results were statistically significant. Overall, our findings revealed that dexmedetomidine may mitigate inflammation, oxidative stress, and renal dysfunction in mice with SAKI by upregulating the Pink1/Park2-mediated autophagy pathway. …”
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18556
Image 1_Exploring the antibacterial and anti-biofilm properties of Diacerein against methicillin-resistant Staphylococcus aureus.tif
Published 2025“…Background<p>Methicillin-resistant Staphylococcus aureus (MRSA) poses a significant clinical challenge due to its multidrug resistance. …”
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18557
ERICC Policy Brief_ Supporting children’s mental health and wellbeing in and through education in contexts of conflict and protracted crises
Published 2025“…., 2013), potentially decreasing attendance and retention rates as well as learning quality and continuity. …”
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18558
Data Sheet 4_Lathyrol inhibits the proliferation of Renca cells by altering expression of TGF-β/Smad pathway components and subsequently affecting the cell cycle.xlsx
Published 2025“…The TGF-β/Smad signaling pathway plays a significant role in the development and progression of RCC.…”
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18559
Data Sheet 3_Global, regional, and national burdens of pancreatitis in children and adolescents aged 0–24 years from 1992 to 2021: a trend analysis based on the global burden of di...
Published 2025“…Background<p>The younger onset of pancreatitis presents a significant public health challenge. This study aims to analyze the global burden of pancreatitis in younger populations based on the Global Burden of Disease 2021.…”
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18560
Table 1_Specific drugs for rare diseases in a province of eastern China under catalog management: from 2021 to 2023.docx
Published 2025“…The allocation of 19 drugs increased significantly, and 19 drugs were newly developed. The overall procurement cost of drugs increased and then decreased, which may be related to national policies. …”