Image 1_T2 cytokine-driven alarmin and antiviral responses in asthma: insights into immune modulation and the role of IL-4Rα targeting.jpeg by Jelena Pesic (21216791)

“…Chronic exposure to T2 cytokines following RV infection significantly decreased TSLP and IFNλ1 but increased IFNβ, specifically in asthmatic BECs.…”

DataSheet1_Polystyrene microplastics exposition on human placental explants induces time-dependent cytotoxicity, oxidative stress and metabolic alterations.pdf by Ashelley Kettyllem Alves de Sousa (20293452)

“…Levels of mitochondrial and total superoxide anion (p < 0.01 and p < 0.05, respectively) and hydrogen peroxide (p < 0.001) were significantly elevated. PS-MP exposure resulted in a reduction in total sulfhydryl content (p < 0.05) and the activities of antioxidant enzymes superoxide dismutase (p < 0.01) and catalase (p < 0.05), while glutathione peroxidase activity increased (p < 0.05), and the oxidized/reduced glutathione ratio decreased (p < 0.05). …”

Data Sheet 1_hERG activators exhibit antitumor effects in breast cancer through calcineurin and β-catenin-mediated signaling pathways.doc by Yan Yu (56143)

“…Background<p>Breast cancer remains a leading cause of mortality among women worldwide, with existing therapeutic options often accompanied by significant side effects and a persistent risk of disease recurrence. …”

Supplementary file 1_Biodegradation potential of Gordonia spp. on polypropylene and polystyrene: enhanced degradation through pretreatment.docx by Yan Zhu (112437)

“…Introduction<p>As extensively utilized synthetic polymers, polypropylene (PP) and polystyrene (PS) have raised significant environmental concerns due to their persistent accumulation in ecosystems.…”

Data Sheet 1_Genome-wide association analysis of grain iron and zinc in rice grown under agroclimatic sites with contrasting soil iron status.pdf by Sonu (17999809)

“…Grain Fe content along with Zn is a major contemporary breeding objective in rice in order to tackle micronutrient deficiency. …”

The impact of refractive error correction on health-related quality of life in nursing home residents in Armenia by Aida Giloyan (16826909)

“…</p> <p></p><p>Visual impairment and blindness in nursing home residents were higher compared to proportions found in a nationwide survey in Armenia and globally.</p><p>Participants who had corrected their vision reported significantly better physical and mental health at follow-up compared to baseline.…”

Data Sheet 1_Beat-to-beat coronary wave intensity analysis: implications of backward waves originating from microvascular.docx by Xinzhou Xie (587158)

“…Compared to rest, adenosine-induced hyperemia significantly increased cBCW (1.88 ± 1.46 ×10⁴ W/m²s vs. 2.31 ± 1.74 × 10⁴ W/m²s, p < 0.001) and peak backward compression wave intensity (pBCW) (4.30 ± 4.61 ×10⁵ W/m²s² vs. 5.21 ± 4.68 × 10⁵ W/m²s², p = 0.008), while significantly decreasing peak backward decompression wave intensity (pBDW) (5.41 ± 6.06 × 10⁵ W/m²s² vs. 3.99 ± 4.64 × 10⁵ W/m²s², p < 0.001), with no significant effect on cBDW. …”

Discriminatory learning preferentially enhances reward associated input. by Rahul Garg (3064578)

“…(E) Fraction of glomeruli with significant changes post learning. Yellow: increased, dark grey: decreased, light grey: unchanged. …”

Data Sheet 1_Resistance characteristics of culture-positive tuberculosis from 2015 to 2022.xlsx by Zhenzhen Wang (250368)

“…The overall TB resistance rates were significantly higher in the main urban areas. During the study period, the proportion of mono-resistance tuberculosis (MR-TB), multidrug-resistant tuberculosis (MDR-TB) and polydrug-resistant tuberculosis (PDR-TB) decreased by 59.2% (12.9–5.3%), 40.3% (12.4–7.4%), and 68.3% (6.9–2.2%), respectively. …”

Table 1_Aerobic exercise ameliorates atherosclerosis-induced cognitive impairment via hippocampal IL-33/NF-κB signaling modulation.xlsx by Jianwei Peng (811819)

“…Then, AS mice were divided into sedentary (AS-SED) and exercise (AS-EX) groups for a 10-week aerobic exercise intervention. Results showed significant aortic plaques and cognitive deficits in AS mice after 6 weeks on the HFHCD diet. …”

Data Sheet 1_Aerobic exercise ameliorates atherosclerosis-induced cognitive impairment via hippocampal IL-33/NF-κB signaling modulation.xlsx by Jianwei Peng (811819)

“…Then, AS mice were divided into sedentary (AS-SED) and exercise (AS-EX) groups for a 10-week aerobic exercise intervention. Results showed significant aortic plaques and cognitive deficits in AS mice after 6 weeks on the HFHCD diet. …”

Molecular features influencing clinical outcome of advanced HER2-positive gastric cancer receiving trastuzumab plus chemotherapy by Yu Lei (266919)

“…Additionally, after treatment, TMB significantly increased in non-responders, while CIN significantly decreased in responders.…”

Supplementary file 2_Quantile regression application to identify key determinants of malnutrition in five West African countries of Gabon, Gambia, Liberia, Mauritania, and Nigeria.... by Reshav Beni (21422981)

“…Background<p>Malnutrition remains one of the most pressing health challenges, particularly in developing nations across Africa, placing a significant burden on both public health agencies and the affected countries. …”

Supplementary file 1_Quantile regression application to identify key determinants of malnutrition in five West African countries of Gabon, Gambia, Liberia, Mauritania, and Nigeria.... by Reshav Beni (21422981)

“…Background<p>Malnutrition remains one of the most pressing health challenges, particularly in developing nations across Africa, placing a significant burden on both public health agencies and the affected countries. …”

Statistical data. by Bo Yang (104813)

“…The results show that: (1) Habitat quality shows significant gradient characteristics, and the overall decreases from southeast to northwest. …”

Sensitivity of land types to threat factors. by Bo Yang (104813)

“…The results show that: (1) Habitat quality shows significant gradient characteristics, and the overall decreases from southeast to northwest. …”

Direction variability for each replicate and sub-replicate. by Damien Genettais (21387230)

“…<p>When slugs migrated towards light (<b>A</b>) direction variability decreased significantly with the increased number of cells (p-value<10⁻³) within slugs for all replicates. …”

Proteomic analysis of _sEVs. by María-Angélica Calderón-Peláez (2851865)

“…C) Regarding the biological processes, the significantly increased proteins were involved in immune response, while decreased proteins were mainly involved in cell adhesion and developmental processes. …”

Data Sheet 1_Real-time evaluation of antibacterial efficacy using bioluminescent assays for Pseudomonas aeruginosa and Staphylococcus aureus.pdf by Manali Patil (22142128)

“…Treatment with cefotaxime resulted in a significant reduction of the bioluminescent signal in P. aeruginosa compared to untreated controls, while doxycycline induced a delayed growth curve. …”

Data_Sheet_1_The association between Geriatric Nutritional Risk Index and KSD disease: results from National Health and Nutrition Examination Survey 2007–2018.ZIP by Zhicheng Tang (7010534)

“…</p>Conclusion<p>The study underscores a significant, albeit nonlinear, association between elevated GNRI levels and decreased KSD prevalence. …”