Candidate genes by Genome-wide CRISPR Screen. by Mingyi Xu (5575871)

“…<div><p>Human cytomegalovirus (HCMV) is a herpes virus with a long replication cycle. HCMV encoded long non-coding RNA termed RNA2.7 is the dominant transcript with a length of about 2.5kb, accounting for 25% of total viral transcripts. …”

Data Sheet 1_Particulate matter pollution and older adult health: global trends and disparities, 1991–2021.docx by Qiong Yi (3931826)

“…Females consistently experienced higher age-standardized DALYs rate than males for both APMP and HAP-SF across all regions and years. APMP burden showed a weak negative correlation with the Socio-demographic Index (SDI) at the regional level (r = −0.25, p < 0.001) but no significant correlation at the country level. …”

Table 5_Effects of dietary NDF/NFC ratios on in vitro rumen fermentation, methane emission, and microbial community composition.docx by Jichao Li (1973251)

“…As the NDF/NFC ratios increased, total gas production decreased linearly. The degradation rates of dry matter (DM), neutral detergent fiber (NDF), and acid detergent fiber (ADF) decreased, showing a quadratic response (p = 0.018). …”

Table 1_Effects of dietary NDF/NFC ratios on in vitro rumen fermentation, methane emission, and microbial community composition.docx by Jichao Li (1973251)

“…As the NDF/NFC ratios increased, total gas production decreased linearly. The degradation rates of dry matter (DM), neutral detergent fiber (NDF), and acid detergent fiber (ADF) decreased, showing a quadratic response (p = 0.018). …”

Table 4_Effects of dietary NDF/NFC ratios on in vitro rumen fermentation, methane emission, and microbial community composition.docx by Jichao Li (1973251)

“…As the NDF/NFC ratios increased, total gas production decreased linearly. The degradation rates of dry matter (DM), neutral detergent fiber (NDF), and acid detergent fiber (ADF) decreased, showing a quadratic response (p = 0.018). …”

Table 6_Effects of dietary NDF/NFC ratios on in vitro rumen fermentation, methane emission, and microbial community composition.docx by Jichao Li (1973251)

“…As the NDF/NFC ratios increased, total gas production decreased linearly. The degradation rates of dry matter (DM), neutral detergent fiber (NDF), and acid detergent fiber (ADF) decreased, showing a quadratic response (p = 0.018). …”

Table 3_Effects of dietary NDF/NFC ratios on in vitro rumen fermentation, methane emission, and microbial community composition.docx by Jichao Li (1973251)

“…As the NDF/NFC ratios increased, total gas production decreased linearly. The degradation rates of dry matter (DM), neutral detergent fiber (NDF), and acid detergent fiber (ADF) decreased, showing a quadratic response (p = 0.018). …”

Table 2_Effects of dietary NDF/NFC ratios on in vitro rumen fermentation, methane emission, and microbial community composition.docx by Jichao Li (1973251)

“…As the NDF/NFC ratios increased, total gas production decreased linearly. The degradation rates of dry matter (DM), neutral detergent fiber (NDF), and acid detergent fiber (ADF) decreased, showing a quadratic response (p = 0.018). …”

FLEXI interactions with RNA-binding proteins. by Jun Yao (9646)

“…RNA-binding sites: I, within introns corresponding to FLEXIs; SS-I and SS-E, bimodally enriched across the 5’- and 3’ splice sites in unspliced pre-mRNAs with the midpoints in the intron or flanking exon (SS-I and SS-E, respectively; Figs <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1011416#pgen.1011416.g004" target="_blank">4A</a> and <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1011416#pgen.1011416.s011" target="_blank">S11</a>). mRNA levels, RBPs whose knockdown resulted in significant difference in mRNA levels (increased or decreased, DESeq2 |LFC|≥1, adjusted p≤0.05) from host gene of FLEXIs with a binding site for that RBP compared to those genes whose transcripts lacked a binding site for the same RBPs based on ENCODE RBP-knockdown datasets (p≤0.05 calculated by Fisher’s exact test; <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1011416#pgen.1011416.s013" target="_blank">S13 Fig</a>). …”

Image 2_Low-frequency electroacupuncture attenuates methamphetamine-induced depressive-like behaviors and cognitive impairment via modulating neuroinflammation.tif by Jingyi Zhang (741111)

“…</p>Discussion<p>The present study suggested that EA alleviates METH-induced depressive-like behaviors and cognitive impairment by modulating neuroinflammation, particularly through the inhibition of microglial activation and pro-inflammatory cytokine release. EA may represent a promising non-pharmacological strategy for the treatment of METH-associated neuropsychiatric disorders.…”

Image 6_Low-frequency electroacupuncture attenuates methamphetamine-induced depressive-like behaviors and cognitive impairment via modulating neuroinflammation.tif by Jingyi Zhang (741111)

“…</p>Discussion<p>The present study suggested that EA alleviates METH-induced depressive-like behaviors and cognitive impairment by modulating neuroinflammation, particularly through the inhibition of microglial activation and pro-inflammatory cytokine release. EA may represent a promising non-pharmacological strategy for the treatment of METH-associated neuropsychiatric disorders.…”

Image 4_Low-frequency electroacupuncture attenuates methamphetamine-induced depressive-like behaviors and cognitive impairment via modulating neuroinflammation.tif by Jingyi Zhang (741111)

“…</p>Discussion<p>The present study suggested that EA alleviates METH-induced depressive-like behaviors and cognitive impairment by modulating neuroinflammation, particularly through the inhibition of microglial activation and pro-inflammatory cytokine release. EA may represent a promising non-pharmacological strategy for the treatment of METH-associated neuropsychiatric disorders.…”

Image 5_Low-frequency electroacupuncture attenuates methamphetamine-induced depressive-like behaviors and cognitive impairment via modulating neuroinflammation.tif by Jingyi Zhang (741111)

“…</p>Discussion<p>The present study suggested that EA alleviates METH-induced depressive-like behaviors and cognitive impairment by modulating neuroinflammation, particularly through the inhibition of microglial activation and pro-inflammatory cytokine release. EA may represent a promising non-pharmacological strategy for the treatment of METH-associated neuropsychiatric disorders.…”

Data Sheet 1_Membrane filtration reduces nutrient availability and invasion potential in drinking water systems, without affecting mature biofilms.docx by Thomas Pluym (22046237)

“…<p>Ensuring biostable drinking water is a growing priority for drinking water utilities, especially in non- or minimally chlorinated distribution systems where microbial regrowth is controlled through nutrient limitation. …”

Image 3_Low-frequency electroacupuncture attenuates methamphetamine-induced depressive-like behaviors and cognitive impairment via modulating neuroinflammation.tif by Jingyi Zhang (741111)

“…</p>Discussion<p>The present study suggested that EA alleviates METH-induced depressive-like behaviors and cognitive impairment by modulating neuroinflammation, particularly through the inhibition of microglial activation and pro-inflammatory cytokine release. EA may represent a promising non-pharmacological strategy for the treatment of METH-associated neuropsychiatric disorders.…”

Image 1_Low-frequency electroacupuncture attenuates methamphetamine-induced depressive-like behaviors and cognitive impairment via modulating neuroinflammation.tif by Jingyi Zhang (741111)

“…</p>Discussion<p>The present study suggested that EA alleviates METH-induced depressive-like behaviors and cognitive impairment by modulating neuroinflammation, particularly through the inhibition of microglial activation and pro-inflammatory cytokine release. EA may represent a promising non-pharmacological strategy for the treatment of METH-associated neuropsychiatric disorders.…”

Preeclamptic plasma disrupts endothelial function and promotes inflammation in endothelial cells: beneficial effects of glibenclamide and MCC950 in this scenario by Karoliny Nune Santos (21752603)

“…<p>Preeclampsia (PE) is characterized by systemic endothelial dysfunction and remains a significant clinical challenge. Activation of NLRP3 inflammasome, reactive oxygen species (ROS) production, and pyroptosis and autophagy are important mechanisms in this condition. …”

Data Sheet 2_Secreted PD-L1 alleviates inflammatory arthritis in mice through local and systemic AAV gene therapy.docx by Wenjun Li (41954)

“…The levels of pro-inflammatory cytokines in blood were also significantly decreased in shPD-L1 treated mice. Additionally, T cell apoptosis rates in the spleen showed a 2-fold increase in treated mice. …”

Data Sheet 1_Secreted PD-L1 alleviates inflammatory arthritis in mice through local and systemic AAV gene therapy.pdf by Wenjun Li (41954)

“…The levels of pro-inflammatory cytokines in blood were also significantly decreased in shPD-L1 treated mice. Additionally, T cell apoptosis rates in the spleen showed a 2-fold increase in treated mice. …”

Image 2_Viral encephalitis and seizures cause rapid depletion of neuronal progenitor cells and alter neurogenesis in the adult mouse dentate gyrus.tif by Alberto Pauletti (10920690)

“…They resumed proliferation at 14 dpi, but, did not recover to CTR levels, and displayed aberrant migration patterns. (2) The number of proliferating NSCs significantly decreased within the dorsal DG of TMEV mice at 14 dpi compared to CTR, while (3) a heightened population of proliferating astrocytes was observed. …”