Structure-guided engineering and molecular simulations to design a potent monoclonal antibody to target aP2 antigen for adaptive immune response instigation against type 2 diabetes by Abbas Khan (5141000)

“…The objective was to engineer the CA33 monoclonal antibody for effective targeting of the aP2 antigen, aiming to elicit a potent immune response. This approach involved screening a mutational landscape comprising 57 mutants to identify modifications that yield significant enhancements in binding efficacy and stability.…”

Therapeutic and diagnostic applications of exosomal circRNAs in breast cancer by Mohanraj Gopikrishnan (17773449)

“…Additionally, circRNAs can interact with proteins and modulate their functions including signaling pathways involved in the initiation and development of cancer. …”

Sunitinib induces PTEN expression and inhibits PDGFR signaling and migration of medulloblastoma cells by Castellino, R.C.

“…However, sunitinib did not induce apoptosis in either cell line at any time point, indicating that the anti-migratory effects of sunitinib were not due to impeding cell survival. …”
Get full text
Get full text
Get full text
Get full text

Modulation of SLFN11 induces changes in DNA Damage response in breast cancer by Christophe Michel Raynaud (17449906)

“…The use of a CRISPR-dCas9 UNISAM and KRAB system could increase or decrease SLFN11 expression significantly (up to fivefold), stably and specifically in BT-549 and T47D cancer cell lines. …”

The effect of Ramadan focused education on patients with type 2 diabetes: A systematic review and meta-analysis by Hoda Gad (6470522)

“…</p><h3>Conclusions</h3><p dir="ltr">This systematic review and meta-analysis shows that Ramadan-focused diabetes education leads to a decrease in HbA1c and LDL, but an increase in TG and weight during Ramadan. …”

Hedonic valuation of land protection methods: implications for cluster development. by Kling, Robert

“…The key findings of the study are: (i) proximity to national or state park land and to city or county open space has a significant positive impact on property values, while proximity to national forest land or to privately conserved land exhibits no significant effects; and, (ii) inclusion of a property within a cluster development decreases its value by 17 to 26 %. …”
Get full text

Renal Function Decline in Recipients and Donors of Kidney Grafts by Bahous, Sola Aoun

“…Background/Aims: Renal function decreases over time as a result of reduction in the number of functioning nephrons with age. …”
Get full text
Get full text
Get full text
Get full text

Research on the potential of photovoltaic technologies in reducing energy consumption in an urban mixed use residential community. A Case study for net zero energy community in Dub... by SUGATHAN, SANAL

“…The outcome of these events, abundant regional solar irradiation and drop in global PV prices has led to the significant developments and innovations in the solar energy sector. …”
Get full text

Chemopreventive potential of the pentane-based fraction of wild carrot oil against chemically-induced squamous cell carcinoma by Shebaby, W.

“…Additionally, F2 treatment with the three doses significantly decreased the papilloma volume at weeks 15, 18 and 21 (p < 0.05, p < 0.01 and p < 0.01, respectively). …”
Get full text
Get full text
Get full text
Get full text

Effect of temperature on the rheological properties of neat aqueous Wyoming sodium bentonite dispersions by Vryzas, Zisis

“…Temperature affects significantly the rheological behavior of neat water Wyoming Na-bentonite dispersions. …”
Get full text
Get full text
Get full text
Get full text

Salicylic acid restricts mercury translocation by activating strong antioxidant defense mechanisms in sweet pepper (Capsicum annum L.) by Muhammad Fasih Khalid (10652246)

“…H₂O₂ was found to be lower in plants treated with SA under Hg toxicity than in non-treated plants. The SA application also restricts the accumulation of Hg in sweet pepper roots, leaves, and fruits. …”

Unpacking the asymmetric impact of exchange rate volatility on trade flows: A study of selected developed and developing Asian economies by Umar Nawaz Kayani (17131781)

“…The non-linear models yielded more significant findings, while the linear models did not indicate any significant effects of exchange rate volatility on trade flows. …”

Rapid mercury removal using living indigenous microalgal communities for water treatment applications by Amr Nasr Fekry (22521185)

“…Advanced characterization revealed significant surface modifications, with Scanning Electron Microscopy (SEM) showing increased surface roughness, Fourier Transform Infrared Spectroscopy (FTIR) indicating involvement of hydroxyl, protein, and carbohydrate functional groups, and X-ray Photoelectron Spectroscopy (XPS) confirming Hg(II) binding to oxygen-containing moieties with distinctive Hg 4f peaks at 101.78 and 105.8 eV. …”

Multi-IsnadSet MIS for Sahih Muslim Hadith with chain of narrators, based on multiple ISNAD by Aziz Mehmood Farooqi (20748788)

“…<p>In the Islamic domain, Hadiths hold significant importance, standing as crucial texts following the Holy Quran. …”

Effect of Flexural NSM-FRP Bars on the Shear Strength of Reinforced Concrete Beams by Saleh, Rayyan Bashar

Get full text

Qatar’s immigrants at higher risk of diabetes by Nature Research (16552612)

“…“We are currently assessing novel tools for a larger scale, quick and non-invasive screening programme for diabetes in the Qatari population."…”

Activation of Src kinase in primary colorectal carcinoma An indicator of poor clinical prognosis by Allgayer, Heike

“…In patients who underwent curative resection, a significant correlation with a decreased disease-free survival rate was found (P < 0.0001). …”
Get full text
Get full text
Get full text

Evaluating the impact of the Minimization of Aggression and Violence (MoAV) intervention on mechanical restraint use in Qatar's acute mental health setting by Ananth Nazarene (21239912)

“…The percentage of restrained patients decreased from 25 % to 4 %, p = (<0.001). The mean duration of restraint incidents slightly increased from 59.1 min in 2016 to 61.3 min in 2021, though this change was not statistically significant. …”

GATA3: Orchestrating cellular fate through differentiation and proliferation by Rim Bacha (14779420)

“…By elucidating the complex interactions governed by GATA3, this underscores its significance in maintaining cellular <u>homeostasis</u>. …”

Changes in Blood microRNA Expression and Early Metabolic Responsiveness 21 Days Following Bariatric Surgery by Stephen L. Atkin (6684368)

“…MicroRNA expression was determined by quantitative polymerase chain reaction and tested for significant changes after surgery.</p><p dir="ltr"><br></p><h3>Results: </h3><p dir="ltr">BMI decreased by 3.8 kg/m² 21 days postoperatively. …”