Image 1_T2 cytokine-driven alarmin and antiviral responses in asthma: insights into immune modulation and the role of IL-4Rα targeting.jpeg by Jelena Pesic (21216791)

“…Chronic exposure to T2 cytokines following RV infection significantly decreased TSLP and IFNλ1 but increased IFNβ, specifically in asthmatic BECs.…”

DataSheet1_Polystyrene microplastics exposition on human placental explants induces time-dependent cytotoxicity, oxidative stress and metabolic alterations.pdf by Ashelley Kettyllem Alves de Sousa (20293452)

“…Levels of mitochondrial and total superoxide anion (p < 0.01 and p < 0.05, respectively) and hydrogen peroxide (p < 0.001) were significantly elevated. PS-MP exposure resulted in a reduction in total sulfhydryl content (p < 0.05) and the activities of antioxidant enzymes superoxide dismutase (p < 0.01) and catalase (p < 0.05), while glutathione peroxidase activity increased (p < 0.05), and the oxidized/reduced glutathione ratio decreased (p < 0.05). …”

Data Sheet 1_hERG activators exhibit antitumor effects in breast cancer through calcineurin and β-catenin-mediated signaling pathways.doc by Yan Yu (56143)

“…Background<p>Breast cancer remains a leading cause of mortality among women worldwide, with existing therapeutic options often accompanied by significant side effects and a persistent risk of disease recurrence. …”

Effect of miR-7974 mimic transfection on proliferation of MDA-MB-453 cells together with changes in protein and gene expression levels of LC3B. by Stralina Eneh (21213312)

“…<b>(B)</b> The fold change of total protein levels of LC3B between negative control/cells only samples and miR-7974-treated samples were statistically significant. <b>(C)</b> The gene expression levels of <i>LC3B</i> were decreased 72h after miR-7974 transfection of MBA-MB-453 cells compared to the negative control/cells-only samples. …”

Data Sheet 1_Burn inhalation injury and intubation with dexamethasone-eluting endotracheal tubes modulate local microbiome and alter airway inflammation.xlsx by Gabriela Gonzales (19756103)

“…Inflammatory markers IFN-γ, IL-4, and IL-1β were elevated in dexamethasone-ETT groups at 3 days, then decreased by 7 days. Macrophage markers CD86 and CD206 were significantly greater in dexamethasone groups compared to regular ETT groups at 7 days (p = 0.002 and p = 0.0213, respectively). …”

Table 4_Global, regional, and national epidemiology of Intracerebral Hemorrhage among women of childbearing age (1990–2021): incidence, mortality, DALYs, and risk factor analysis.x... by Yuan Li (67017)

“…Background and Objectives<p>Intracerebral Hemorrhage (ICH) is a serious cerebrovascular condition that poses a significant health risk to women of childbearing age (WCBA) globally. …”

Supplementary file 1_Biodegradation potential of Gordonia spp. on polypropylene and polystyrene: enhanced degradation through pretreatment.docx by Yan Zhu (112437)

“…Introduction<p>As extensively utilized synthetic polymers, polypropylene (PP) and polystyrene (PS) have raised significant environmental concerns due to their persistent accumulation in ecosystems.…”

Image_1_Impact of fat intake on [18F]AlF-NOTA-FAPI-04 uptake in normal abdominal organs.TIF by Jiashun Dai (20137596)

“…Purpose<p>[¹⁸F]AlF-NOTA-FAPI-04 demonstrates significant physiological uptake in the gallbladder and biliary tract system, representing a limitation of this positron emission tomography (PET) tracer. …”

Table 2_Global, regional, and national epidemiology of Intracerebral Hemorrhage among women of childbearing age (1990–2021): incidence, mortality, DALYs, and risk factor analysis.x... by Yuan Li (67017)

“…Background and Objectives<p>Intracerebral Hemorrhage (ICH) is a serious cerebrovascular condition that poses a significant health risk to women of childbearing age (WCBA) globally. …”

Data Sheet 1_Impact of individualized and structured aerobic exercise on clinical outcomes in pediatric congenital heart diseases with post-surgical rehabilitation: a meta-analysis... by Ayoola Awosika (22687004)

“…Background<p>Children with congenital heart defects (CHD) commonly experience decreased exercise capacity due to structural heart abnormalities, surgical interventions, and parental-and physician-imposed activity restrictions. …”

Table 1_The boundaries between PML and PML-IRIS: difficult to define, pathology may predict.docx by Jiamin Chen (388522)

“…</p>Results<p>Notably, 63.2% (12/19) of them had blood CD4+ T-cell counts < 200 cells/μl, and 36.8% (7/19) had ≥ 200 cells/μl. 52.9% (9/17) of the patients had elevated CSF protein, 5.3% (1/19) had decreased CSF glucose. Statistical analysis revealed significant correlations between mass effect and both blood CD4+ T-cell counts (P = 0.022) and CSF protein levels (P < 0.001). …”

Supplementary Material for: Trends and Impact of Early Medical Complications in Acute Ischemic Stroke: Data from the Austrian Stroke Unit Registry by figshare admin karger (2628495)

“…Pneumonia (4.2%), UTI (2.9%), cardiac arrhythmia (1.4%), and decompensated heart failure (1.4%) were most common, with significant declines in prevalences over time. Admission NIHSS scores decreased, and the use of intravenous thrombolysis and mechanical thrombectomy increased. …”

Data Sheet 1_Mechanistic insights into pyrolysis temperature-dependent lead (Pb) stabilization in phytoremediation residue-derived biochar.docx by Jin Liu (12833)

“…<p>The substantial generation of hazardous, metal-enriched biomass residues poses significant risks of secondary contamination, presenting a critical bottleneck to the broader implementation of phytoremediation that urgently requires effective treatment solutions. …”

Results for the EPIC bowel subscale and the EORTC QLQ PR25 bowel symptoms scale. by John N. Staffurth (20636565)

“…This is also reflected in the mean and median QoL scores (w.r.t. the right-hand axis), which decreased in magnitude with time also.</p>…”

Data Sheet 1_Genome-wide association analysis of grain iron and zinc in rice grown under agroclimatic sites with contrasting soil iron status.pdf by Sonu (17999809)

“…Additionally, the response of these lines to Fe toxicity was assessed at one location.</p>Results<p>Significant phenotypic variation for both traits was observed. …”

Table 4_The boundaries between PML and PML-IRIS: difficult to define, pathology may predict.docx by Jiamin Chen (388522)

“…</p>Results<p>Notably, 63.2% (12/19) of them had blood CD4+ T-cell counts < 200 cells/μl, and 36.8% (7/19) had ≥ 200 cells/μl. 52.9% (9/17) of the patients had elevated CSF protein, 5.3% (1/19) had decreased CSF glucose. Statistical analysis revealed significant correlations between mass effect and both blood CD4+ T-cell counts (P = 0.022) and CSF protein levels (P < 0.001). …”

Table 1_Efficacy and safety of esketamine in patients undergoing painless gastrointestinal endoscopy: a systematic review and meta-analysis of randomized controlled trials.doc by Qi Zhang (28502)

“…Significantly increased postoperative dizziness occurred, particularly at doses ≥0.3 mg/kg, with no significant association to postoperative nausea/vomiting or drowsiness.…”

Table 1_Impacts of climate change on chronic respiratory health in Ethiopia: a systematic review and meta-analysis.docx by Zewudu Andualem (8602434)

“…Study design influenced prevalence estimates, with cross-sectional studies reporting higher rates (46%) than case–control studies (14%). Significant heterogeneity (I² = 99%, p < 0.001) was observed across studies.…”

Table 1_Isowighteone attenuates vascular calcification by targeting HSP90AA1-mediated PI3K-Akt pathway and suppressing osteogenic gene expression.xls by Yuanxi Mo (22090130)

“…(F. hispida, Moraceae), has demonstrated significant anti-inflammatory properties in prior studies. …”

The impact of refractive error correction on health-related quality of life in nursing home residents in Armenia by Aida Giloyan (16826909)

“…Those who had not corrected their vision reported no significant improvement in both PHC and MHC. There were no significant differences in baseline to follow-up mean change scores for PHC and MHC between those who corrected their vision and those who had not.…”