QbD-based co-loading of paclitaxel and imatinib mesylate by protamine-coated PLGA nanoparticles effective on breast cancer cells by Neha Laxane (19851759)

“…</p> <p>A sustained zero-order drug release was obtained for both the formulations.…”

Supplementary file 1_Characterization of the gut microbiota in people with different levels of obesity.docx by Ergan Li (22142026)

“…Purpose<p>With the evolution of dietary habits, obesity has emerged as a significant global health issue. Numerous studies have demonstrated a close association between obesity and gut microbiota; however, the specific contribution of gut microbiota to varying degrees of obesity remains inadequately understood. …”

Sustained increase in the levels of pro-inflammatory cytokine and chemokine in the testis correlate with systemic inflammation. by Stefanos Giannakopoulos (15628394)

“…Pearson coefficient >0.6 was considered a significant correlation.</p>…”

Image 1_NGF/ERK signaling-mediated epigenetic regulation of neuropathic pain in the cerebrospinal fluid-contacting nucleus.tif by Guangling Li (6931880)

“…Statistical analysis was performed, with significance set at a p-value of < 0.05.</p>Results<p>CI induced significant upregulation of NGF in the CSF-CN. …”

Data Sheet 1_Effect of liraglutide on the dysglycemia, inflammation, and gut microbiota in prediabetic KKay mice.docx by Ying Zhang (40767)

“…<p>Prediabetes is a significant risk factor for type 2 diabetes mellitus (T2DM). …”

Ecological risk level and area from 2000 to 2020. by Yin Yu (3139023)

“…The results show that (1) the landscape pattern changed visibly from 2000 to 2020, the comprehensive land-use dynamics increased from 8.53% to 9.66%, and the land use dynamics are greatest and change most dramatically on construction sites; (2) the landscape ecological risk level of the study area as a whole showed a declining trend, and 96.82% of the ecological risk plot index decreased, and the risk distribution was dominated by lower risk, medium risk and higher risk areas; (3) landscape ecological risk was spatially positively correlated across all time periods, and the spatial aggregation was gradually weakened, with the distribution of LH and HL areas dispersed and the distribution of HH and LL areas concentrated. …”

Supplementary Material for: Incorporating ALBI Grade with Geriatric Nutritional Risk Index Enhances Hepatocellular Carcinoma Risk Stratification by Nam H. (17688795)

“…This risk stratification showed a significant correlation with OS for each BCLC stage (all P < 0.001), except for stage D (P = 0.082). …”

Enhanced Anthropogenic Contributions to Marine Aerosols and trace elements Compared to Coastal Regions in Northern China by Yang Zhou (17600586)

“…<p dir="ltr"><a href="" target="_blank">Terrestrial aerosols,</a> transported by westerly winds from Asian continent, continuously deliver both natural and anthropogenic nutrients to downstream marine ecosystems. …”

Supplementary Material for: Adjuvant Lip Gauze Wet Dressing Restores Lip Barrier Function and Improves Atopic Cheilitis by figshare admin karger (2628495)

“…Results indicated that patients exhibited decreased lip barrier function, which improved significantly with gauze wet dressing, enhancing hydration and normalizing pH levels within 30 minutes. …”

Data Sheet 1_Comprehensive analysis on the regulatory mechanism of active ingredient accumulation during fermentation process of Massa Medicata Fermentata: microbe and metabolic pr... by Yun Li (692280)

“…</p>Results<p>During the fermentation process, bacterial diversity generally shows an increasing trend, whereas fungal diversity generally shows a decreasing trend. Revealing that the differentially abundant metabolites were primarily categorized into lipids, amino acids and derivatives, phenolic acids, organic acids, flavonoids, lignans and coumarins, nucleotides and derivatives, and alkaloids. …”

DataSheet1_Diverse responses of hypoxia-inducible factor alpha mRNA abundance in fish exposed to low oxygen: the importance of reporting methods.CSV by Taylor E. Murphy (19800534)

“…<p>Low dissolved oxygen (hypoxia) poses significant challenges to aquatic ecosystems, affecting the behavior, reproduction, and survival of aquatic organisms. …”

Oral L-Arginine Treatment Attenuates <i>Cryptococcus neoformans</i> Extrapulmonary Dissemination and Disease Progression by Adithap Hansakon (21708473)

“…We found significant depletion of serum L-arginine and its downstream metabolites, accompanied by increased arginase activity in infected tissues, indicating a disrupted metabolic balance. …”

Data Sheet 1_Ultra-small curcumin-ruthenium coordination polymer nanodots prevent renal ischemia-reperfusion injury and the progression to chronic kidney disease.docx by Xian Liu (191882)

“…The results indicated that Ru/Cur nanodots effectively eliminated various ROS and demonstrated significant therapeutic effects and biocompatibility in IR-AKI mice, reducing markers of kidney function damage, alleviating renal oxidative stress, and decreasing inflammatory cell infiltration. …”

Image1_Diverse responses of hypoxia-inducible factor alpha mRNA abundance in fish exposed to low oxygen: the importance of reporting methods.PDF by Taylor E. Murphy (19800534)

“…<p>Low dissolved oxygen (hypoxia) poses significant challenges to aquatic ecosystems, affecting the behavior, reproduction, and survival of aquatic organisms. …”

Area of land use types from 2000 to 2020. by Yin Yu (3139023)

“…The results show that (1) the landscape pattern changed visibly from 2000 to 2020, the comprehensive land-use dynamics increased from 8.53% to 9.66%, and the land use dynamics are greatest and change most dramatically on construction sites; (2) the landscape ecological risk level of the study area as a whole showed a declining trend, and 96.82% of the ecological risk plot index decreased, and the risk distribution was dominated by lower risk, medium risk and higher risk areas; (3) landscape ecological risk was spatially positively correlated across all time periods, and the spatial aggregation was gradually weakened, with the distribution of LH and HL areas dispersed and the distribution of HH and LL areas concentrated. …”

Table1_Diverse responses of hypoxia-inducible factor alpha mRNA abundance in fish exposed to low oxygen: the importance of reporting methods.DOCX by Taylor E. Murphy (19800534)

“…<p>Low dissolved oxygen (hypoxia) poses significant challenges to aquatic ecosystems, affecting the behavior, reproduction, and survival of aquatic organisms. …”

Video 1_Complement activation drives the phagocytosis of necrotic cell debris and resolution of liver injury.mp4 by Sofie Vandendriessche (638514)

“…Importantly, C3 deficiency led to a significant accumulation of necrotic debris and impairment of liver recovery in mice, which was attributed to decreased phagocytosis of debris by recruited neutrophils in vivo. …”

Supplementary Material for: Effect of endobronchial valve treatment on skeletal muscles, fatigue, and sleep in severe emphysema patients by figshare admin karger (2628495)

“…Intercostal thickening fraction did not change following treatment. Fatigue decreased significantly, reducing severe fatigue prevalence from 70% to 25%. …”

Data Sheet 1_Mechanism of salidroside promoting testosterone secretion induced by H2O2 in TM3 Leydig cells based on metabolomics and network pharmacology.zip by Zixu Wang (6297470)

“…<p>Oxidative stress-induced damage is a significant contributor to the impairment of Leydig cells in the testes, potentially diminishing the secretion of testosterone and other androgens, thereby resulting in testosterone deficiency. …”

Supplementary file 1_Meta-analysis of Xiaoyao formula as an adjuvant therapy for treating postpartum depression.docx by Jing Liu (38537)

“…Additionally, XYF as an adjuvant therapy also significantly decreased Hamilton Depression Scale scores (standard mean difference [SMD] -1.69; 95% CI -2.37 to -1.01).…”