Search alternatives:
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
point decrease » point increase (Expand Search)
part decrease » bfrt decreased (Expand Search), a decrease (Expand Search), pa decreased (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
point decrease » point increase (Expand Search)
part decrease » bfrt decreased (Expand Search), a decrease (Expand Search), pa decreased (Expand Search)
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IQGAP1 is a protein that plays a critical role in regulating the level of apoptosis in endothelial cells.
Published 2025“…<p>(A) The Annexin V–FITC/propidium iodide (PI) assay results indicate that Si-IQGAP1 can slightly decrease the apoptosis rate of normal cells, whereas knocking down IQGAP1 in PA-induced cells (PA + Si-IQGAP1) can significantly reduce the apoptosis rate. …”
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Abnormal expression of IQGAP1, cleaved caspase-3, BCL‐2, and BAX in the aortic wall of HFD mice and AS plaque.
Published 2025“…(D) The TUNEL assay demonstrates significantly increased numbers of apoptotic cells in the aortas of HFD mice. …”
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Inhibiting IQGAP1 expression restricts atherosclerotic plaque development.
Published 2025“…(D) The TUNEL assay demonstrates that the number of apoptotic cells are significantly decreased in the AAV-Si-IQGAP1 group. (E,F) Western blot and densitometric analyses of each protein relative to β‐actin reveal decreased expression of IQGAP1, and pro-apoptotic proteins (cleaved caspase-3 and BAX), while YAP and the anti-apoptotic protein BCL-2 are increased in the aortic wall of the AAV-Si-IQGAP1 groups. …”
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