Surface motility assays illustrating the swimming. by Techit Thavorasak (13138440)

Growth characteristics of <i>A. baumannii</i> strains used in this study. by Techit Thavorasak (13138440)

Cut-point analysis using Youden’s J Index. by Dandan Gong (5744666)

“…The optimal cut-off point of the CD4⁺ count was 50 Nr/μl or less. …”

Virucidal activity of LA, SCFA, and succinic acid combinations associated with an optimal vaginal microbiota or BV, representing a non-optimal vaginal microbiota. by Muriel Aldunate (22411177)

Sequencing analysis confirming the mutation in the smpB gene of <i>Acinetobacter baumannii.</i> by Techit Thavorasak (13138440)

IL-33 supplementation fails to prevent trTreg reduction in established infection. by Santiago Boccardo (5927954)

Information of core targets. by Guobing Wang (288885)

“…Transwell Experiments to verify the migration rate of Hela cells at different time points of action. Hela cell apoptosis was determined by a Tunel assay. …”

Composition of Scutellaria Barbata. by Guobing Wang (288885)

“…Transwell Experiments to verify the migration rate of Hela cells at different time points of action. Hela cell apoptosis was determined by a Tunel assay. …”

GO function enrichment analysis. by Guobing Wang (288885)

“…Transwell Experiments to verify the migration rate of Hela cells at different time points of action. Hela cell apoptosis was determined by a Tunel assay. …”

KEGG functional enrichment analysis. by Guobing Wang (288885)

“…Transwell Experiments to verify the migration rate of Hela cells at different time points of action. Hela cell apoptosis was determined by a Tunel assay. …”

Competition experiments between the wild-type strain and the Δ<i>corA</i> mutant of <i>Salmonella</i>. by Selma Metaane (12329248)

An Integrated Approach for Determination of Total Per- and Polyfluoroalkyl Substances (PFAS) by Marzieh Shojaei (11084912)

“…In soils, the total PFAS estimated with results from an extraction method utilizing sequential acidic and basic solvents led to a 35% increase in precursors during TOP assay relative to results from a basic solvent only extraction in one of three soils tested, but concentrations did not increase significantly in remaining soils. …”

TMS recapitulates epigenetic age predictions and tissue-dependent effects identified via other technologies. by Amy Longtin (21409957)

<i>Ctsz</i>^{<i>−/−</i>} mice have higher lung burden and earlier spleen dissemination during acute infection followed by greater chronic inflammation and mortality risk.... by Rachel K. Meade (22216529)

Receiver operating characteristic (ROC) curves. by Dandan Gong (5744666)

“…The optimal cut-off point of the CD4⁺ count was 50 Nr/μl or less. …”

DataSheet7_Novel Starting Points for Human Glycolate Oxidase Inhibitors, Revealed by Crystallography-Based Fragment Screening.ZIP by Sabrina R. Mackinnon (12496324)

“…The fragment hits were verified to bind and inhibit HAO1 in solution by fluorescence-based activity assay and surface plasmon resonance. Further optimization cycle by crystallography and biophysical assays have generated two hit compounds of micromolar (44 and 158 µM) potency that do not compete with the substrate and provide attractive starting points for the development of potent and selective HAO1 inhibitors.…”

DataSheet6_Novel Starting Points for Human Glycolate Oxidase Inhibitors, Revealed by Crystallography-Based Fragment Screening.ZIP by Sabrina R. Mackinnon (12496324)

“…The fragment hits were verified to bind and inhibit HAO1 in solution by fluorescence-based activity assay and surface plasmon resonance. Further optimization cycle by crystallography and biophysical assays have generated two hit compounds of micromolar (44 and 158 µM) potency that do not compete with the substrate and provide attractive starting points for the development of potent and selective HAO1 inhibitors.…”

DataSheet4_Novel Starting Points for Human Glycolate Oxidase Inhibitors, Revealed by Crystallography-Based Fragment Screening.ZIP by Sabrina R. Mackinnon (12496324)

“…The fragment hits were verified to bind and inhibit HAO1 in solution by fluorescence-based activity assay and surface plasmon resonance. Further optimization cycle by crystallography and biophysical assays have generated two hit compounds of micromolar (44 and 158 µM) potency that do not compete with the substrate and provide attractive starting points for the development of potent and selective HAO1 inhibitors.…”

DataSheet5_Novel Starting Points for Human Glycolate Oxidase Inhibitors, Revealed by Crystallography-Based Fragment Screening.ZIP by Sabrina R. Mackinnon (12496324)

“…The fragment hits were verified to bind and inhibit HAO1 in solution by fluorescence-based activity assay and surface plasmon resonance. Further optimization cycle by crystallography and biophysical assays have generated two hit compounds of micromolar (44 and 158 µM) potency that do not compete with the substrate and provide attractive starting points for the development of potent and selective HAO1 inhibitors.…”

DataSheet1_Novel Starting Points for Human Glycolate Oxidase Inhibitors, Revealed by Crystallography-Based Fragment Screening.PDF by Sabrina R. Mackinnon (12496324)

“…The fragment hits were verified to bind and inhibit HAO1 in solution by fluorescence-based activity assay and surface plasmon resonance. Further optimization cycle by crystallography and biophysical assays have generated two hit compounds of micromolar (44 and 158 µM) potency that do not compete with the substrate and provide attractive starting points for the development of potent and selective HAO1 inhibitors.…”