Roxadustat has risks of reversible central hypothyroidism in patients undergoing hemodialysis: a single-center retrospective cohort study حسب Emiko Otsuka (7519313)

"…Here, we retrospectively analyzed thyroid-stimulating hormone (TSH), free thyroxine (FT4), and free triiodothyronine (FT3) levels in 51 patients (mean age: 72.3 ± 10.7 years; 58.8% male) undergoing hemodialysis before, during, and after halting roxadustat treatment. TSH levels were significantly decreased from a median of 2.46 (interquartile range:1.60–4.51) mU/L before roxadustat treatment to 1.36 (0.72–2.41) mU/L during treatment (<i>p</i> < 0.001), and improved to 2.56 (1.78–4.63) mU/L after halting roxadustat (<i>p</i> < 0.001). …"

Image 8_Vitamin D protects spermatogonia and Sertoli cells from heat stress damage by inhibiting NLRP3.tif حسب Han Chu (7417343)

"…Phase II, both the siRNA + heat stress and VD + heat stress groups showed decreased apoptosis in spermatogonia and Sertoli cells, lower inflammatory factor levels, increased BCL-2 expression, and decreased NLRP3 expression compared to the heat stress-only group, with statistically significant differences (P < 0.05).…"

Image 4_NET-EN treatment leads to delayed HSV-2 infection, enhanced mucin and T cell functions in the female genital tract when compared to DMPA in a preclinical mouse model.tiff حسب M. Firoz Mian (10013314)

"…However, DMPA significantly decreased the total number of VT CD4+ and CD8+ T cells and the number of IFN-γ producing CD4 and CD8 T cells and increased the percentage of CD4 and CD8 T cells producing TNF-α compared to untreated mice. …"

DataSheet1_The short-chain fatty acid receptors Gpr41/43 regulate bone mass by promoting adipogenic differentiation of mesenchymal stem cells.pdf حسب Friederike Behler-Janbeck (3384488)

"…MicroCT scanning of femoral bones of Gpr41/43 dKO mice revealed a significant increase of trabecular bone volume and trabecular compared to WT controls. …"

Data Sheet 1_How low can you go? Antibiotic use in Swedish dogs with gastroenteritis.pdf حسب Ditte Ljungquist (20446670)

"…During the same period, the all-cause mortality rates decreased significantly for all CGE consultations, implicating that this level of antibiotic use do not compromise patient safety. …"

Image 9_Vitamin D protects spermatogonia and Sertoli cells from heat stress damage by inhibiting NLRP3.tif حسب Han Chu (7417343)

"…Phase II, both the siRNA + heat stress and VD + heat stress groups showed decreased apoptosis in spermatogonia and Sertoli cells, lower inflammatory factor levels, increased BCL-2 expression, and decreased NLRP3 expression compared to the heat stress-only group, with statistically significant differences (P < 0.05).…"

Table_1_Effects of high-intensity interval training in a cold environment on arterial stiffness and cerebral hemodynamics in sedentary Chinese college female students post-COVID-19... حسب Xiangyuan Chen (9658136)

"…In contrast, in the control group, the concentrations of cerebral oxygenated hemoglobin and total hemoglobin significantly decreased during left leg support (p < 0.05). …"

Table 1_Decadal trends and regional disparities in tuberculosis burden: a comprehensive analysis of global, African, and Southeast Asian data from the GBD 1990–2021.docx حسب Shiwei Xie (3617159)

"…The annual percentage change (APC) was calculated to assess the significance of temporal trends.</p>Results<p>From 1990 to 2021, global age-standardized rates of TB declined markedly, with ASIR decreasing from 173.0 to 103.0 per 100,000, ASMR from 40.0 to 14.0, and ASDR from 1,650.6 to 580.3. …"

Image 12_Vitamin D protects spermatogonia and Sertoli cells from heat stress damage by inhibiting NLRP3.tif حسب Han Chu (7417343)

"…Phase II, both the siRNA + heat stress and VD + heat stress groups showed decreased apoptosis in spermatogonia and Sertoli cells, lower inflammatory factor levels, increased BCL-2 expression, and decreased NLRP3 expression compared to the heat stress-only group, with statistically significant differences (P < 0.05).…"

Image 11_Vitamin D protects spermatogonia and Sertoli cells from heat stress damage by inhibiting NLRP3.tif حسب Han Chu (7417343)

"…Phase II, both the siRNA + heat stress and VD + heat stress groups showed decreased apoptosis in spermatogonia and Sertoli cells, lower inflammatory factor levels, increased BCL-2 expression, and decreased NLRP3 expression compared to the heat stress-only group, with statistically significant differences (P < 0.05).…"

Table 2_Vitamin D protects spermatogonia and Sertoli cells from heat stress damage by inhibiting NLRP3.xlsx حسب Han Chu (7417343)

"…Phase II, both the siRNA + heat stress and VD + heat stress groups showed decreased apoptosis in spermatogonia and Sertoli cells, lower inflammatory factor levels, increased BCL-2 expression, and decreased NLRP3 expression compared to the heat stress-only group, with statistically significant differences (P < 0.05).…"

Table 1_Effect of cholecalciferol on immune and vascular function in non-diabetic chronic kidney disease.docx حسب Kajal Kamboj (12769602)

"…A significant increase in mRNA expression of vitamin D-responsive genes (cathelicidin, IL-10, VDR, and CYP27B1) was observed. …"

Data Sheet 1_Serum levels of per- and polyfluoroalkylated substances and methylation of DNA from peripheral blood.pdf حسب Hanane Omichessan (4991552)

"…The strongest association was found between PFOA serum levels and decreased DNAm at cg06874740 (p-value_Bonferroni = 2.2×10⁻⁵) and between PFOS serum levels and decreased DNAm at cg02793158 (p-value_Bonferroni = 9.3×10⁻⁵). …"

Long-term impact of molecular epidemiology shifts of methicillin-resistant <i>Staphylococcus aureus</i> on severity and mortality of bloodstream infection حسب Norihito Kaku (7439288)

"…Over this 16-year period, SCC<i>mec</i> type II decreased significantly from 79.2% to 15.5%, while type IV increased from 18.2% to 65.5%. …"

Data Sheet 1_Dangua Fang induces anti-glucolipid metabolism disorder effects similar to those of direct NFIL3 inhibition.zip حسب Zhuang Han (471130)

"…The NFIL3 mRNA and protein expression levels in the serum, liver, and small intestine were significantly decreased. The relative abundance of Bacteroidota decreased, whereas that of Firmicutes increased, and changes in the gut microbiota significantly correlated with serum total cholesterol (TC), triglyceride (TG), and free fatty acid (FFA) levels. …"

Data Sheet 3_How low can you go? Antibiotic use in Swedish dogs with gastroenteritis.pdf حسب Ditte Ljungquist (20446670)

"…During the same period, the all-cause mortality rates decreased significantly for all CGE consultations, implicating that this level of antibiotic use do not compromise patient safety. …"

Table 4_Vitamin D protects spermatogonia and Sertoli cells from heat stress damage by inhibiting NLRP3.docx حسب Han Chu (7417343)

"…Phase II, both the siRNA + heat stress and VD + heat stress groups showed decreased apoptosis in spermatogonia and Sertoli cells, lower inflammatory factor levels, increased BCL-2 expression, and decreased NLRP3 expression compared to the heat stress-only group, with statistically significant differences (P < 0.05).…"

Supplementary Material for: Characterisation of an ischaemia-reperfusion model for the formation of a stage II pressure injury in diabetic mice حسب figshare admin karger (2628495)

"…On day 10, db/db mice exhibited delayed wound closure, as well as impaired regeneration of the panniculus carnosus and dermis, with significantly decreased mRNA levels of VEGF and HSP90. …"

Table 6_Vitamin D protects spermatogonia and Sertoli cells from heat stress damage by inhibiting NLRP3.xlsx حسب Han Chu (7417343)

"…Phase II, both the siRNA + heat stress and VD + heat stress groups showed decreased apoptosis in spermatogonia and Sertoli cells, lower inflammatory factor levels, increased BCL-2 expression, and decreased NLRP3 expression compared to the heat stress-only group, with statistically significant differences (P < 0.05).…"

Data Sheet 2_How low can you go? Antibiotic use in Swedish dogs with gastroenteritis.pdf حسب Ditte Ljungquist (20446670)

"…During the same period, the all-cause mortality rates decreased significantly for all CGE consultations, implicating that this level of antibiotic use do not compromise patient safety. …"