Data Sheet 1_Integrated transcriptomic analysis identifies lactylation-linked gemcitabine resistance and therapeutic targets in intrahepatic cholangiocarcinoma.docx by Wenwei Xie (1987225)

“…The high group associated with resistance showed significantly worse survival outcomes, with a positive correlation between resistance and lactylation levels. …”

Image 3_Polymorphous corneal dystrophy subtype 3 and keratoconus aggravation after corneal refractive surgery in a three-generation family carrying both ZEB1 and ZNF469 pathogenic... by Qinghong Lin (14162640)

“…One year later, visual acuity of III1 decreased significantly with KC aggravation and corneal opacification. …”

Table 1_Electroacupuncture improves scopolamine hydrobromide induced dry eye in mice via inhibiting ocular surface inflammation and regulating the HMGB1-related signaling pathways.... by Xia Wu (203682)

“…The levels of HMGB1, RAGE, TLR2, TLR4, and IL-6 were significantly decreased while IL-10 level was significantly increased after EA treatment, indicating that EA may improve dry eye surface inflammation by inhibiting HMGB1-related signaling pathways.…”

Image 2_Polymorphous corneal dystrophy subtype 3 and keratoconus aggravation after corneal refractive surgery in a three-generation family carrying both ZEB1 and ZNF469 pathogenic... by Qinghong Lin (14162640)

“…One year later, visual acuity of III1 decreased significantly with KC aggravation and corneal opacification. …”

Table 1_Artificial grassland establishment alters soil organic carbon fractions and cbbL-type carbon-sequestering microbial communities.xlsx by Linge Shan (22805624)

“…Compared to CK, both grassland types increased the relative abundance of Actinobacteria but decreased that of Planctomycetes. At the genus level, LG significantly enriched SinoRhizobium and MesoRhizobium, whereas GG promoted Microvirga and Bradyrhizobium.…”

Table 2_TSG-6 promotes healing of critical-sized bone defects in mice.xlsx by Oliver Küppers (22742732)

“…Treatment with 50 μg rTSG-6 significantly enhanced bone formation compared to untreated and low-dose (10 µg) controls at 35 days post-injury. …”

Table 2_Impact of chemoradiotherapy for first primary lung cancer on the prognosis and re-chemoradiotherapy sensitivity of second primary lung cancer.docx by Zhe Chen (196097)

“…</p>Results<p>The competitive risk model indicated that FPLC radiotherapy and chemotherapy did not significantly change the risk of developing SPLC. However, the Cox proportional hazards model revealed that FPLC radiotherapy was associated with decreased overall survival (OS; HR=1.251, P<0.001) and cancer-specific survival (CSS; HR=1.228, P=0.001) in patients with SPLC. …”

Data Sheet 1_Patient engagement in radiation oncology: a large retrospective study of survey response dynamics.docx by Bailey A. Loving (20573882)

“…MVA showed that higher socioeconomic disadvantage significantly decreased survey participation (ADI third tertile vs. first tertile OR=0.708, p<0.001), with each unit increase in ADI reducing the odds of completion by 1% (p<0.001). …”

Data Sheet 1_Hybridization promotes growth performance by altering rumen microbiota and metabolites in sheep.docx by Rui Zhang (13940)

“…Acetate, propionate, and total volatile fatty acid (VFA) concentrations in the DH group were higher than those in the HH group, whereas NH₃-N concentration decreased in the DH and SH groups. Metagenomic analysis revealed that several Prevotella and Fibrobacter species were significantly more abundant in the DH group, contributing to an increased ability to degrade dietary cellulose and enrich their functions in enzymes involved in carbohydrate breakdown. …”

Data Sheet 1_TSG-6 promotes healing of critical-sized bone defects in mice.pdf by Oliver Küppers (22742732)

“…Treatment with 50 μg rTSG-6 significantly enhanced bone formation compared to untreated and low-dose (10 µg) controls at 35 days post-injury. …”

Data Sheet 1_Impact of chemoradiotherapy for first primary lung cancer on the prognosis and re-chemoradiotherapy sensitivity of second primary lung cancer.xlsx by Zhe Chen (196097)

“…</p>Results<p>The competitive risk model indicated that FPLC radiotherapy and chemotherapy did not significantly change the risk of developing SPLC. However, the Cox proportional hazards model revealed that FPLC radiotherapy was associated with decreased overall survival (OS; HR=1.251, P<0.001) and cancer-specific survival (CSS; HR=1.228, P=0.001) in patients with SPLC. …”

Table 3_Impact of chemoradiotherapy for first primary lung cancer on the prognosis and re-chemoradiotherapy sensitivity of second primary lung cancer.docx by Zhe Chen (196097)

“…</p>Results<p>The competitive risk model indicated that FPLC radiotherapy and chemotherapy did not significantly change the risk of developing SPLC. However, the Cox proportional hazards model revealed that FPLC radiotherapy was associated with decreased overall survival (OS; HR=1.251, P<0.001) and cancer-specific survival (CSS; HR=1.228, P=0.001) in patients with SPLC. …”

DataSheet1_HER2 expression in different cell lines at different inoculation sites assessed by [52Mn]Mn-DOTAGA(anhydride)-trastuzumab.docx by Toàn Minh Ngô (21195116)

“…The ratios for orthotopic HER2-positive tumors were significantly higher than those for ectopic HER2-negative tumors and melanoma at all time points. …”

Table 3_TSG-6 promotes healing of critical-sized bone defects in mice.xlsx by Oliver Küppers (22742732)

“…Treatment with 50 μg rTSG-6 significantly enhanced bone formation compared to untreated and low-dose (10 µg) controls at 35 days post-injury. …”

Data Sheet 2_TSG-6 promotes healing of critical-sized bone defects in mice.pdf by Oliver Küppers (22742732)

“…Treatment with 50 μg rTSG-6 significantly enhanced bone formation compared to untreated and low-dose (10 µg) controls at 35 days post-injury. …”

Data Sheet 1_Artificial grassland establishment alters soil organic carbon fractions and cbbL-type carbon-sequestering microbial communities.xlsx by Linge Shan (22805624)

“…Compared to CK, both grassland types increased the relative abundance of Actinobacteria but decreased that of Planctomycetes. At the genus level, LG significantly enriched SinoRhizobium and MesoRhizobium, whereas GG promoted Microvirga and Bradyrhizobium.…”

Table 1_Microbial diversity and community assembly in heavy metal-contaminated soils: insights from selenium-impacted mining areas.xlsx by Zhiyong Wang (313131)

“…Heavy metal pollution significantly impacts soil microbial communities due to its persistence and long-term residual effects. …”

Data Sheet 1_High spatial resolution gene expression profiling and characterization of neuroblasts migrating in the peri-injured cortex using photo-isolation chemistry.docx by Takuya Miyamoto (567070)

“…Experiments using primary cultured neuroblasts showed that application of TGF-β significantly decreased proliferating cells labeled with BrdU. …”

Data Sheet 1_Effects of stand structure and soil depth on soil properties in Cryptomeria japonica plantations.xlsx by Laicong Luo (12521938)

“…Moreover, soils in stands with good structure exhibited higher organic carbon and total nitrogen contents, particularly in the surface soil layer (0–10 cm), while the C:N, C:P, and N:P ratios gradually decreased with increasing soil depth. The study demonstrated that maintaining a good stand structure—characterized by low canopy closure, high understory vegetation cover, and moderate stand density—can significantly improve soil porosity, water-holding capacity, and nutrient cycling efficiency. …”

Data Sheet 1_Features and rhizosphere colonization strategies of Lactobacillus plantarum 0308 in soil-tomato systems.docx by Xiancui Zhang (8349426)

“…Further analyses revealed that LP0308 altered the rhizosphere soil microbial community, significantly increasing the abundance of Bacillus spp. while decreasing the potential pathogenic microorganisms, such as Ralstonia solanacearum and Fusarium oxysporum. …”