Image 2_Benign regulation of short-chain fatty acids: the underlying mechanism of the beneficial effects of manual acupuncture on cognitive ability and the intestinal mucosal barri... by Ning Ding (456674)

“…The destruction of the intestinal mucosal barrier caused by a decrease in short-chain fatty acids (SCFAs) plays a key role in gut microbiota dysbiosis-induced neuroinflammation in AD. …”

Supplementary file 2_Patient-specific and interpretable deep brain stimulation optimisation using MRI and clinical review data.xlsx by Apostolos Mikroulis (22473742)

“…Background<p>Optimisation of Deep Brain Stimulation (DBS) settings is a key aspect in achieving clinical efficacy in movement disorders, such as the Parkinson’s disease. Modern techniques attempt to solve the problem through data-intensive statistical and machine learning approaches, adding significant overhead to the existing clinical workflows. …”

Supplementary file 3_Patient-specific and interpretable deep brain stimulation optimisation using MRI and clinical review data.zip by Apostolos Mikroulis (22473742)

“…Background<p>Optimisation of Deep Brain Stimulation (DBS) settings is a key aspect in achieving clinical efficacy in movement disorders, such as the Parkinson’s disease. Modern techniques attempt to solve the problem through data-intensive statistical and machine learning approaches, adding significant overhead to the existing clinical workflows. …”

Supplementary file 1_Patient-specific and interpretable deep brain stimulation optimisation using MRI and clinical review data.docx by Apostolos Mikroulis (22473742)

“…Background<p>Optimisation of Deep Brain Stimulation (DBS) settings is a key aspect in achieving clinical efficacy in movement disorders, such as the Parkinson’s disease. Modern techniques attempt to solve the problem through data-intensive statistical and machine learning approaches, adding significant overhead to the existing clinical workflows. …”

Table 1_A prospective pilot study on plasma amyloid beta oligomers and postoperative delirium.docx by YoungSoon Yang (7912403)

“…Introduction<p>Postoperative delirium (POD) is common in older adults and has been linked to Alzheimer’s disease (AD). Plasma amyloid-β oligomers (AβOs) may clarify this relationship. …”

Table 2_A prospective pilot study on plasma amyloid beta oligomers and postoperative delirium.docx by YoungSoon Yang (7912403)

“…Introduction<p>Postoperative delirium (POD) is common in older adults and has been linked to Alzheimer’s disease (AD). Plasma amyloid-β oligomers (AβOs) may clarify this relationship. …”

Table 1_Hesperidin alleviates hypothyroidism-related cardiac dysfunction by targeting cardiac miRNAs, Nrf2/NF-κB signaling, oxidative stress and inflammation.docx by Asmaa M. Gaber (21640814)

“…</p>Results<p>CMZ intake resulted in a significant decrease in thyroid hormones (THs) levels with a subsequent increase in serum thyroid stimulating hormone and cardiac enzymes activities, dyslipidemia, and body weight gain. …”

Table 1_Pandemic predisposing influence for feline lower urinary disorders.xlsx by Carolina C. L. Paulino (21546620)

“…The DP group demonstrated a statistically significant decrease in relapses (p < 0.001) and mortality (p < 0.05) compared to the BP group. …”

Table 2_Pandemic predisposing influence for feline lower urinary disorders.xlsx by Carolina C. L. Paulino (21546620)

“…The DP group demonstrated a statistically significant decrease in relapses (p < 0.001) and mortality (p < 0.05) compared to the BP group. …”

Examples for potentially CTF modifying pathogenic variants. by Tal Gutman (20477487)

Image 1_Multi-omics analysis reveals the efficacy of two probiotic strains in managing feline chronic kidney disease through gut microbiome and host metabolome.pdf by Hsiao-Wen Huang (2349427)

“…<p>Gut dysbiosis has been implicated in the progression of chronic kidney disease (CKD), yet the functional alterations of the microbiome and their links to host metabolism in feline CKD pathophysiology remain unclear. …”

Table 1_Multi-omics analysis reveals the efficacy of two probiotic strains in managing feline chronic kidney disease through gut microbiome and host metabolome.docx by Hsiao-Wen Huang (2349427)

“…<p>Gut dysbiosis has been implicated in the progression of chronic kidney disease (CKD), yet the functional alterations of the microbiome and their links to host metabolism in feline CKD pathophysiology remain unclear. …”

Data Sheet 1_Association between body mass index at different levels and risk of gastroesophageal reflux disease: a systematic review with dose-response meta-analysis.docx by Mao Yiqing (22686374)

“…The results of the meta-analysis across different BMI groups suggest that, overweight (BMI ≥25 kg/m²) was an important inflection point for the risk of the diseases. In subgroup analyses comparing obese and non-obese populations, we incorporated other obesity diagnostic indicators and found that these might be a significant source of heterogeneity (p = 0.015). …”

Antibodies used in this study. by Kevin J. Kokesh (19859571)

“…Western blot and densitometric analysis showed a significant increase in cathepsin B protein expression in <i>M</i>. …”

Time and flowrate used for proteomics. by Kevin J. Kokesh (19859571)

“…Western blot and densitometric analysis showed a significant increase in cathepsin B protein expression in <i>M</i>. …”

S1 Graphical abstract - by Kevin J. Kokesh (19859571)

“…Western blot and densitometric analysis showed a significant increase in cathepsin B protein expression in <i>M</i>. …”

Key demographics of our dataset comparing the included and dropped data from the BLSA database. by Alison Deatsch (17551947)

Data Sheet 1_Western diet-induced visceral adipose tissue inflammation promotes Alzheimer’s disease pathology via microglial activation in a mouse model.docx by Ji Sun Lim (7254677)

“…However, the mechanistic link between WD-driven eWAT inflammation and Alzheimer’s disease (AD) pathology remains unclear.</p>Methods<p>WD feeding for 20 weeks was conducted to evaluate its effects on AD-related neuroinflammation and pathology in mice. …”

Data Sheet 1_Global burden of Type 2 Diabetes Mellitus attributable to dietary risks in elderly adults: insights from the Global Burden of Disease study 2021.docx by Yiting Tang (2295307)

“…Dietary risk factors, such as high consumption of processed meats and sugar-sweetened beverages and low intake of whole grains and fruits, play a critical role in the burden of T2DM. This study aims to comprehensively quantify the global burden of T2DM attributable to dietary risks among elderly adults, identify significant dietary risk factors driving disease burden, and evaluate temporal, regional, and demographic variations to inform targeted public health strategies and interventions for reducing the impact of T2DM.…”

Table 2_Different association between triglyceride-glucose index and mild cognitive impairment in type 2 diabetes mellitus patients with and without diabetic kidney disease.docx by Songtao Feng (21344366)

“…Aim<p>The triglyceride-glucose (TyG) index, a surrogate marker reflecting metabolic status related to both glucose and lipid homeostasis, has been implicated in the development of diabetes-related complications, including diabetic kidney disease (DKD). …”