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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
related disease » related diseases (Expand Search)
we decrease » _ decrease (Expand Search), a decrease (Expand Search), nn decrease (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
related disease » related diseases (Expand Search)
we decrease » _ decrease (Expand Search), a decrease (Expand Search), nn decrease (Expand Search)
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19861
Table 7_Development and validation of prognostic and diagnostic models utilizing immune checkpoint-related genes in public datasets for clear cell renal cell carcinoma.xlsx
Published 2025“…Background<p>Clear cell renal cell carcinoma (ccRCC) is the most prevalent subtype of renal cell carcinoma, and immune checkpoint regulator-based immunotherapy has emerged as an effective treatment for advanced stages of the disease. However, the expression patterns, prognostic significance, and diagnostic value of immune checkpoint-related genes (ICRGs) in ccRCC remain underexplored. …”
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19862
Table 1_Development and validation of prognostic and diagnostic models utilizing immune checkpoint-related genes in public datasets for clear cell renal cell carcinoma.docx
Published 2025“…Background<p>Clear cell renal cell carcinoma (ccRCC) is the most prevalent subtype of renal cell carcinoma, and immune checkpoint regulator-based immunotherapy has emerged as an effective treatment for advanced stages of the disease. However, the expression patterns, prognostic significance, and diagnostic value of immune checkpoint-related genes (ICRGs) in ccRCC remain underexplored. …”
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19863
Table 2_Development and validation of prognostic and diagnostic models utilizing immune checkpoint-related genes in public datasets for clear cell renal cell carcinoma.docx
Published 2025“…Background<p>Clear cell renal cell carcinoma (ccRCC) is the most prevalent subtype of renal cell carcinoma, and immune checkpoint regulator-based immunotherapy has emerged as an effective treatment for advanced stages of the disease. However, the expression patterns, prognostic significance, and diagnostic value of immune checkpoint-related genes (ICRGs) in ccRCC remain underexplored. …”
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19864
Table 3_Development and validation of prognostic and diagnostic models utilizing immune checkpoint-related genes in public datasets for clear cell renal cell carcinoma.xlsx
Published 2025“…Background<p>Clear cell renal cell carcinoma (ccRCC) is the most prevalent subtype of renal cell carcinoma, and immune checkpoint regulator-based immunotherapy has emerged as an effective treatment for advanced stages of the disease. However, the expression patterns, prognostic significance, and diagnostic value of immune checkpoint-related genes (ICRGs) in ccRCC remain underexplored. …”
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19865
Table 5_Development and validation of prognostic and diagnostic models utilizing immune checkpoint-related genes in public datasets for clear cell renal cell carcinoma.xlsx
Published 2025“…Background<p>Clear cell renal cell carcinoma (ccRCC) is the most prevalent subtype of renal cell carcinoma, and immune checkpoint regulator-based immunotherapy has emerged as an effective treatment for advanced stages of the disease. However, the expression patterns, prognostic significance, and diagnostic value of immune checkpoint-related genes (ICRGs) in ccRCC remain underexplored. …”
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19866
Table 4_Development and validation of prognostic and diagnostic models utilizing immune checkpoint-related genes in public datasets for clear cell renal cell carcinoma.xlsx
Published 2025“…Background<p>Clear cell renal cell carcinoma (ccRCC) is the most prevalent subtype of renal cell carcinoma, and immune checkpoint regulator-based immunotherapy has emerged as an effective treatment for advanced stages of the disease. However, the expression patterns, prognostic significance, and diagnostic value of immune checkpoint-related genes (ICRGs) in ccRCC remain underexplored. …”
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19867
Table 8_Development and validation of prognostic and diagnostic models utilizing immune checkpoint-related genes in public datasets for clear cell renal cell carcinoma.xlsx
Published 2025“…Background<p>Clear cell renal cell carcinoma (ccRCC) is the most prevalent subtype of renal cell carcinoma, and immune checkpoint regulator-based immunotherapy has emerged as an effective treatment for advanced stages of the disease. However, the expression patterns, prognostic significance, and diagnostic value of immune checkpoint-related genes (ICRGs) in ccRCC remain underexplored. …”
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19868
Table 6_Development and validation of prognostic and diagnostic models utilizing immune checkpoint-related genes in public datasets for clear cell renal cell carcinoma.xlsx
Published 2025“…Background<p>Clear cell renal cell carcinoma (ccRCC) is the most prevalent subtype of renal cell carcinoma, and immune checkpoint regulator-based immunotherapy has emerged as an effective treatment for advanced stages of the disease. However, the expression patterns, prognostic significance, and diagnostic value of immune checkpoint-related genes (ICRGs) in ccRCC remain underexplored. …”
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19869
Data Sheet 1_Global, regional, and national epidemiology of otitis media in children from 1990 to 2021.docx
Published 2025“…Background<p>Otitis media(OM) is a prevalent ear condition, particularly among children, with a significant impact on quality of life. This study aimed to elucidate the global prevalence and disability-adjusted life years (DALYs) associated with OM in the 0–14 age group from 1990–2021, using data from the 2021 Global Burden of Disease (GBD) study.…”
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19870
Table 1_Iron deposition is associated with motor and non-motor network breakdown in parkinsonism.xlsx
Published 2025“…Network and iron deposition status were evaluated in relation to diagnostic groups, motor and non-motor symptoms. …”
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19871
Data Sheet 1_Genome-wide DNA methylation analysis identifies kidney epigenetic dysregulation in a cystinosis mouse model.pdf
Published 2025“…Recent studies suggest that epigenetic modifications, particularly DNA methylation (DNAm), play a critical role in the development of chronic kidney disease. We hypothesized that epigenetic dysregulation may contribute to the progression of kidney disease in cystinosis.…”
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19872
Table 1_Genome-wide DNA methylation analysis identifies kidney epigenetic dysregulation in a cystinosis mouse model.xlsx
Published 2025“…Recent studies suggest that epigenetic modifications, particularly DNA methylation (DNAm), play a critical role in the development of chronic kidney disease. We hypothesized that epigenetic dysregulation may contribute to the progression of kidney disease in cystinosis.…”
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19873
Table 3_Genome-wide DNA methylation analysis identifies kidney epigenetic dysregulation in a cystinosis mouse model.xlsx
Published 2025“…Recent studies suggest that epigenetic modifications, particularly DNA methylation (DNAm), play a critical role in the development of chronic kidney disease. We hypothesized that epigenetic dysregulation may contribute to the progression of kidney disease in cystinosis.…”
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19874
Table 2_Genome-wide DNA methylation analysis identifies kidney epigenetic dysregulation in a cystinosis mouse model.docx
Published 2025“…Recent studies suggest that epigenetic modifications, particularly DNA methylation (DNAm), play a critical role in the development of chronic kidney disease. We hypothesized that epigenetic dysregulation may contribute to the progression of kidney disease in cystinosis.…”
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19875
S1_raw_images.
Published 2025“…However, the involvement of miR-122 in regulation of TGF-β signaling and its implication in TGF-β-related HCC metastasis remains obscure. In this study, we demonstrated that miR-122 significantly enhanced the activities of the TGF-β pathway reporter, the levels of phosphorylation of Smad2 and Smad3, and the expression of mesenchymal markers (N-cadherin and vimentin) in HCC cells. …”
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19876
Raw data for graphs.
Published 2025“…However, the involvement of miR-122 in regulation of TGF-β signaling and its implication in TGF-β-related HCC metastasis remains obscure. In this study, we demonstrated that miR-122 significantly enhanced the activities of the TGF-β pathway reporter, the levels of phosphorylation of Smad2 and Smad3, and the expression of mesenchymal markers (N-cadherin and vimentin) in HCC cells. …”
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19877
The predicted AREs in the 3’UTR of ITGAV mRNA.
Published 2025“…However, the involvement of miR-122 in regulation of TGF-β signaling and its implication in TGF-β-related HCC metastasis remains obscure. In this study, we demonstrated that miR-122 significantly enhanced the activities of the TGF-β pathway reporter, the levels of phosphorylation of Smad2 and Smad3, and the expression of mesenchymal markers (N-cadherin and vimentin) in HCC cells. …”
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19878
DataSheet1_AH-6809 mediated regulation of lung adenocarcinoma metastasis through NLRP7 and prognostic analysis of key metastasis-related genes.docx
Published 2024“…Introduction<p>Lung adenocarcinoma (LUAD) has become one of the leading causes of cancer-related deaths globally, with metastasis representing the most lethal stage of the disease. …”
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19879
Table 1_MIND diet score and its association with metabolic dysfunction-associated steatotic liver disease and gut microbiota profiles: a cross-sectional study.docx
Published 2025“…Inflammatory markers (CRP, LPS) decreased with higher adherence (all p < 0.001). Each 1-unit increase in MIND diet score was significantly associated with reductions in fasting insulin (β = −0.20 μU/mL; p < 0.001), HOMA-IR (β = −2.11; p < 0.001), CRP (β = −2.12; p < 0.001), LPS (β = −8.52; p < 0.001). …”
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19880
Table 2_MIND diet score and its association with metabolic dysfunction-associated steatotic liver disease and gut microbiota profiles: a cross-sectional study.docx
Published 2025“…Inflammatory markers (CRP, LPS) decreased with higher adherence (all p < 0.001). Each 1-unit increase in MIND diet score was significantly associated with reductions in fasting insulin (β = −0.20 μU/mL; p < 0.001), HOMA-IR (β = −2.11; p < 0.001), CRP (β = −2.12; p < 0.001), LPS (β = −8.52; p < 0.001). …”