Showing 19,901 - 19,920 results of 23,096 for search '(( significant ((role decrease) OR (fold increases)) ) OR ( significant decrease decrease ))', query time: 0.69s Refine Results
  1. 19901

    Azole drugs have differential efficacy in varied models of immunosuppression in larval zebrafish hosts by Kevin E. Ayala (21979064)

    Published 2025
    “…<p>Fungal infections are an increasing cause of mortality in immunosuppressed human patients, and antifungal drug treatments are still ineffective in a significant percentage of cases. A gap in our understanding of antifungal drug treatment is whether different drugs have differential efficacy in hosts that are experiencing different forms of immunosuppression.…”
  2. 19902

    Table 1_The efficacy and safety of danuglipron and orforglipron in patients with type 2 diabetes and obesity: a systematic review and meta-analysis.docx by Jingjing Zhou (179820)

    Published 2025
    “…Meta-analysis results demonstrated that danuglipron significantly decreased HbA1c (mean difference [MD]: −0.90; 95% CI: −1.06, −0.74), FPG (MD: −24.66; 95% CI: −30.45, −18.86) and weight (MD: −2.17; 95% CI: −3.10, −1.23) and improved FPI (MD: 2.94; 95% CI: 1.50, 4.38). …”
  3. 19903

    Table1_Prediction of the potentially suitable areas of Eucommia ulmoides Oliver in China under climate change based on optimized Biomod2 and MaxEnt models.doc by Guoqiong Cao (20220729)

    Published 2024
    “…<p>Eucommia ulmoides Oliver is a medicinal plant of significant economic importance. Its cortex has been employed for centuries to alleviate various conditions such as lumbar pain, knee pain, and osteoporosis. …”
  4. 19904

    Presentation 1_Global, regional, and national burden of cardiovascular disease attributable to high body mass index from 1990 to 2021 and projection to 2045.pptx by Hui Li (32376)

    Published 2025
    “…Over the study period, the overall CVD burden attributable to HBMI decreased significantly, while the burden of atrial fibrillation and flutter increased. …”
  5. 19905

    Data Sheet 2_Changes in symptom pattern in Meniere's disease by duration: the need for comprehensive management.pdf by Ilmari Pyykkö (2855153)

    Published 2024
    “…The frequency and duration of vertigo attacks generally decreased over time, with attacks becoming shorter and less severe as the disease progressed. …”
  6. 19906

    Table 1_Lumefantrine ameliorates DSS-induced colitis by targeting FLI-1 to suppress NF-κB signaling.docx by Ji Yang (114503)

    Published 2025
    “…Background<p>Current therapeutic options for inflammatory bowel disease (IBD) remain suboptimal due to limited efficacy, significant side effects, and high relapse rates, necessitating novel treatment strategies. …”
  7. 19907

    Image4_Integrating anoikis and ErbB signaling insights with machine learning and single-cell analysis for predicting prognosis and immune-targeted therapy outcomes in hepatocellula... by Huipeng Fang (12587509)

    Published 2024
    “…Background<p>Hepatocellular carcinoma (HCC) poses a significant global health challenge due to its poor prognosis and limited therapeutic modalities. …”
  8. 19908

    Data Sheet 1_Multi level effects of Sanghuang Tongxie Formula on type 2 diabetes rats: a comprehensive analysis from intestinal bacteria to metabolome and transcriptome.xlsx by Jiaxuan Liu (5185280)

    Published 2025
    “…</p>Results<p>SHTX treatment significantly altered the gut microbiota composition in T2DM rats, increasing the relative abundance of Bacteroidetes while decreasing that of Firmicutes, which was closely correlated with improved insulin sensitivity. …”
  9. 19909

    Table1_Myocardial infarction in rats was alleviated by MSCs derived from the maternal segment of the human umbilical cord.DOCX by Shuifen Sun (19855329)

    Published 2024
    “…In rats with MI, maternal-MSCs significantly restored cardiac contractile function and reduced the infarct size. …”
  10. 19910

    Table 2_Association of cardiorespiratory fitness with phenotypic age in younger population: a study based on the NHANES database.docx by Yi Shen (152956)

    Published 2025
    “…</p>Results<p>In the multivariable logistical regression analysis, maintenance of CRF was significantly and inversely associated with PAA, demonstrating a decreased risk of 42% in the high CRF group [OR (95% CI): 0.58 (0.36, 0.96), p = 0.033]. …”
  11. 19911

    Image11_Integrating anoikis and ErbB signaling insights with machine learning and single-cell analysis for predicting prognosis and immune-targeted therapy outcomes in hepatocellul... by Huipeng Fang (12587509)

    Published 2024
    “…Background<p>Hepatocellular carcinoma (HCC) poses a significant global health challenge due to its poor prognosis and limited therapeutic modalities. …”
  12. 19912

    Data Sheet 1_Featured intestinal microbiota associated with hepatocellular carcinoma in various liver disease states.pdf by Xiu Sun (8539698)

    Published 2025
    “…In the CHB-HCC, CC-HCC, and DC-HCC groups, the abundance of Bacteroides, Prevotella, and Faecalibacterium gradually decreased, whereas Klebsiella, Haemophilus, and Streptococcus increased. …”
  13. 19913

    Green Fabrication of Biobased and Degradable Poly(lactic acid)/Poly(butylene succinate) Open-Cell Foams for Highly Efficient Oil–Water Separation with Ultrafast Degradation by Jie Yuan (208425)

    Published 2024
    “…It is notable that different cell structures of varying sizes show significant differences in the adsorption capacity and rate. …”
  14. 19914

    Long-term tillage and cover cropping differentially influenced soil nitrous oxide emissions from cotton cropping system by Debasish Saha (17481384)

    Published 2025
    “…Long-term NT did not significantly (<em>p > 0.05</em>) affect cumulative N<sub>2</sub>O emissions during the study period. …”
  15. 19915

    Image4_Hypoxia-induced PD-L1 expression and modulation of muscle stem cell allograft rejection.JPEG by Jacob Raiten (20021262)

    Published 2024
    “…In vivo, these preconditioned MuSCs led to decreased infiltration of CD4<sup>+</sup> and CD8<sup>+</sup> T cells in implanted limb muscles of mouse models. …”
  16. 19916

    Data Sheet 2_Rapid reshaping of the soil microbiome and metabolome during short-term flooding and draining in rice.docx by Yanyao Lu (22163632)

    Published 2025
    “…The results revealed that S-PPO, S-POD, and S-CAT decreased with prolonged drainage time, whereas the soil redox potential (Eh-mV) and POD increased. …”
  17. 19917

    <i>trus</i> mutant displays higher embryonic lethality. by Saeko Takada (21616085)

    Published 2025
    “…In mutant larvae, we found decreased cell proliferation and growth defects in the brain and imaginal discs. …”
  18. 19918

    Data Sheet 1_The efficacy of ophiopogonanone B in treating the cough in mice infected with Mycoplasma pneumoniae.docx by Nan-Nan Liu (12093551)

    Published 2025
    “…</p>Conclusion<p>By decreasing the expression of TRPA1, SP, and CGRP in the lung tissues of mice afflicted with coughing due to M. pneumoniae infection, ophiopogonanone B effectively alleviated post-infection cough symptoms.…”
  19. 19919

    Data Sheet 1_Antibiofilm potential of plant extracts: inhibiting oral microorganisms and Streptococcus mutans.pdf by Nomi Bartels (20997935)

    Published 2025
    “…P. cretica was able to inhibit and kill S. mutans at a concentration of 0.6 mg/ml, but its effectiveness in biofilm inhibition significantly decreased at 2.5 mg/ml.</p>Discussion<p>The study's hypothesis that all extracts would exhibit an antimicrobial effect was thus confirmed.…”
  20. 19920

    raw data by Boya Gao (21686150)

    Published 2025
    “…Bacterial abundance under moderate and extreme disturbances was significantly lower than that in the control, whereas fungal abundance was significantly higher under extreme disturbance. …”