يعرض 1 - 20 نتائج من 1,746 نتيجة بحث عن '(( significant ((shape based) OR (target based)) ) OR ( significant decrease decrease ))', وقت الاستعلام: 0.12s تنقيح النتائج
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    A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity حسب Wesam S. Ahmed (10170053)

    منشور في 2024
    "…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"
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    Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex حسب Wesam S. Ahmed (10170053)

    منشور في 2022
    "…<p dir="ltr">Coronavirus Disease of 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has resulted in a massive health crisis across the globe, with some genetic variants gaining enhanced infectivity and competitive fitness, and thus significantly aggravating the global health concern. …"
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    Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells حسب Nihal AlMuraikhi (6002234)

    منشور في 2019
    "…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …"
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    Exploring the Significance of Publication-Age-Based Parameters for Evaluating Researcher Impact حسب Ghulam Mustafa (458105)

    منشور في 2023
    "…</p><h2>Other Information</h2><p dir="ltr">Published in: IEEE Access<br>License: <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank">https://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1109/access.2023.3304013" target="_blank">https://dx.doi.org/10.1109/access.2023.3304013</a></p>…"
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    An Efficient Test Vector Compression Technique Based on Geometric Shapes حسب Al Zahir, Saif

    منشور في 2001
    "…In this paper, we introduce a novel compression / decompression scheme based on geometric shapes that substantially reduces the amount of test data and reduces test time. …"
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    article
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    Deep learning-based marine big data fusion for ocean environment monitoring: Towards shape optimization and salient objects detection حسب Sulaiman Khan (12585349)

    منشور في 2023
    "…This research study presents a data fusion-based method for underwater salient object detection and ocean environment monitoring by utilizing a deep model.…"
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    The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu... حسب Wesal Habbab (17346961)

    منشور في 2019
    "…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …"
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    Treating Cancers Using Nature’s Medicine: Significance and Challenges حسب Samson Samuel (6828956)

    منشور في 2021
    "…In recent decades, the emphasis on identifying therapeutic plant-based active principles led to significant advancements in the identification and use of natural compounds to treat various diseases (Figure 1) [2,3]. …"
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    Detection of statistically significant network changes in complex biological networks حسب Raghvendra Mall (581171)

    منشور في 2017
    "…</p><h3>Methods</h3><p dir="ltr">In this paper, we propose an improvement over the state-of-the-art based on the Generalized Hamming Distance adopted for evaluating the topological difference between two networks and estimating its statistical significance. …"
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    Significance of Avicennia Marina in the Arabian Gulf Environment: A Review حسب Kaiprath Puthiyapurayil Haseeba (21392966)

    منشور في 2025
    "…This review addresses the current knowledge gap by providing an overview of Avicennia marina distribution in the Gulf, exploring the significance of its ecosystem services, analyzing the impacts of stressors, and examining conservation and restoration efforts, with attention to nature-based and biotechnological approaches for promoting mangrove growth and conservation in the Gulf.…"
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    Effect of Gd, V, and Y Alloying on the Corrosion Properties of Fe-Mn-Ni-Al Fe-based Shape Memory Alloy حسب Mustafa, Faisal

    منشور في 2024
    "…Significant attention has been given to Fe-based SMA in civil engineering applications due to their high strength and reasonable cost. …"
    احصل على النص الكامل
    article
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    Targeting acute myeloid leukemia cells with novel photosensitive ruthenium-based metal-organic compounds. (c2015) حسب Azar, Daniel Fadi

    منشور في 2016
    "…In this study, we aim to establish a ruthenium-based model for effectively targeting AML, with the goal of later developing approaches to selectively target AML with complexes based on this model. …"
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    احصل على النص الكامل
    masterThesis
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    Nanoparticle enrichment mass-spectrometry proteomics identifies protein-altering variants for precise pQTL mapping حسب Karsten Suhre (67967)

    منشور في 2024
    "…</i>) where we quantify over 18,000 unique peptides from nearly 3000 proteins in more than 320 blood samples from a multi-ethnic cohort in a bottom-up, peptide-centric, mass spectrometry-based proteomics approach. We identify 184 protein-altering variants in 137 genes that are significantly associated with their corresponding variant peptides, confirming target specificity of co-associated affinity binders, identifying putatively causal cis-encoded proteins and providing experimental evidence for their presence in blood, including proteins that may be inaccessible to affinity-based proteomics.…"
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