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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
shape decrease » shape increases (Expand Search), small decrease (Expand Search), step decrease (Expand Search)
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20281
Data Sheet 1_Hyaluronic acid synthase 2 dysfunction exacerbates elastase-induced neutrophilic airway inflammation and emphysema in mice.docx
Published 2025“…After the administration of PPE, the Has2<sup>+/−</sup> mice exhibited a significant increase in total cell and neutrophil counts in the bronchoalveolar lavage fluid samples compared with the WT mice. …”
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20282
Data Sheet 2_Global, regional, and national trends in gastric cancer burden: 1990-2021 and projections to 2040.docx
Published 2024“…Background<p>Gastric cancer (GC) is a common malignancy of the digestive system, with significant geographical variation in its disease burden.…”
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20283
Data Sheet 1_Global, regional, and national trends in gastric cancer burden: 1990-2021 and projections to 2040.docx
Published 2024“…Background<p>Gastric cancer (GC) is a common malignancy of the digestive system, with significant geographical variation in its disease burden.…”
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20284
Table 1_Global, regional, and national trends in gastric cancer burden: 1990-2021 and projections to 2040.xlsx
Published 2024“…Background<p>Gastric cancer (GC) is a common malignancy of the digestive system, with significant geographical variation in its disease burden.…”
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20285
Table 1_Decadal trends and regional disparities in tuberculosis burden: a comprehensive analysis of global, African, and Southeast Asian data from the GBD 1990–2021.docx
Published 2025“…The annual percentage change (APC) was calculated to assess the significance of temporal trends.</p>Results<p>From 1990 to 2021, global age-standardized rates of TB declined markedly, with ASIR decreasing from 173.0 to 103.0 per 100,000, ASMR from 40.0 to 14.0, and ASDR from 1,650.6 to 580.3. …”
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20286
Data Sheet 1_Glycemic variability of glycated hemoglobin in patients with type 2 diabetes mellitus and the risk of cardiovascular diseases: a latest systematic review and meta-anal...
Published 2025“…The standard deviation (SD) of HbA1c was also significantly correlated with a higher risk of cardiovascular events (HR = 1.27, 95% CI: 1.17–1.38, P < 0.00001; OR = 1.30, 95% CI: 1.07–1.57, P = 0.008) and a significant increase in mortality risk (HR = 1.27, 95% CI: 1.17–1.37, P<0.00001). …”
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20287
Supplementary file 1_Glycemic variability of glycated hemoglobin in patients with type 2 diabetes mellitus and the risk of cardiovascular diseases: a latest systematic review and m...
Published 2025“…The standard deviation (SD) of HbA1c was also significantly correlated with a higher risk of cardiovascular events (HR = 1.27, 95% CI: 1.17–1.38, P < 0.00001; OR = 1.30, 95% CI: 1.07–1.57, P = 0.008) and a significant increase in mortality risk (HR = 1.27, 95% CI: 1.17–1.37, P<0.00001). …”
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20288
Supplementary file 2_Glycemic variability of glycated hemoglobin in patients with type 2 diabetes mellitus and the risk of cardiovascular diseases: a latest systematic review and m...
Published 2025“…The standard deviation (SD) of HbA1c was also significantly correlated with a higher risk of cardiovascular events (HR = 1.27, 95% CI: 1.17–1.38, P < 0.00001; OR = 1.30, 95% CI: 1.07–1.57, P = 0.008) and a significant increase in mortality risk (HR = 1.27, 95% CI: 1.17–1.37, P<0.00001). …”
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20289
Table 1_Comparing burden of ischemic stroke caused by high low-density lipoprotein cholesterol in global and China: trends and projections.doc
Published 2025“…</p>Results<p>In 2021, IS deaths due to high LDL-C reached 936,192 globally (an increase of 43.04%) and 300,053 in China (an increase of 161.86%), despite age-standardized mortality rate (ASMR) declining by 43.16% and 12.61%, respectively. …”
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20290
Table 2_Global burden of colorectal cancer attributable to high fasting plasma glucose from 1990 to 2021 and projection to 2040.xlsx
Published 2025“…Further longitudinal studies are essential to validate these trends. Given the significant variations across gender, age, and SDI, targeted interventional strategies should be developed and implemented to effectively manage this disease burden.…”
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20291
Image 1_Global burden of colorectal cancer attributable to high fasting plasma glucose from 1990 to 2021 and projection to 2040.tif
Published 2025“…Further longitudinal studies are essential to validate these trends. Given the significant variations across gender, age, and SDI, targeted interventional strategies should be developed and implemented to effectively manage this disease burden.…”
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20292
Table 1_Global burden of colorectal cancer attributable to high fasting plasma glucose from 1990 to 2021 and projection to 2040.xlsx
Published 2025“…Further longitudinal studies are essential to validate these trends. Given the significant variations across gender, age, and SDI, targeted interventional strategies should be developed and implemented to effectively manage this disease burden.…”
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20293
Table 3_Global burden of colorectal cancer attributable to high fasting plasma glucose from 1990 to 2021 and projection to 2040.xlsx
Published 2025“…Further longitudinal studies are essential to validate these trends. Given the significant variations across gender, age, and SDI, targeted interventional strategies should be developed and implemented to effectively manage this disease burden.…”
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20294
Data Sheet 1_Global trends in fall-induced hip fractures among perimenopausal women 1990 to 2021: results from the global burden of disease study 2021.xlsx
Published 2025“…The burden of disease shows significant regional variations, with a higher burden of disease in regions with high SDI.…”
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20295
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20296
Image 2_Long-term trends and comparison of the burden of lower respiratory tract infections in China and globally from 1990 to 2021: an analysis based on the Global Burden of Disea...
Published 2024“…Compared with the previous period, the COVID-19 pandemic has led to a significant decrease in the disease burden of LRIs. …”
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20297
Table 1_Long-term trends and comparison of the burden of lower respiratory tract infections in China and globally from 1990 to 2021: an analysis based on the Global Burden of Disea...
Published 2024“…Compared with the previous period, the COVID-19 pandemic has led to a significant decrease in the disease burden of LRIs. …”
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20298
Image 1_Long-term trends and comparison of the burden of lower respiratory tract infections in China and globally from 1990 to 2021: an analysis based on the Global Burden of Disea...
Published 2024“…Compared with the previous period, the COVID-19 pandemic has led to a significant decrease in the disease burden of LRIs. …”
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20299
Table 2_Long-term trends and comparison of the burden of lower respiratory tract infections in China and globally from 1990 to 2021: an analysis based on the Global Burden of Disea...
Published 2024“…Compared with the previous period, the COVID-19 pandemic has led to a significant decrease in the disease burden of LRIs. …”
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20300
Table 1_Association of serum iron with all-cause mortality and cardiovascular mortality in the cardiovascular patients: a retrospective cohort study based on the NHANES 1999–2018.d...
Published 2024“…Background<p>Cardiovascular disease (CVD) is one of the leading global causes of death, and serum iron (SI) levels may be associated with the mortality of CVD. …”