Supplementary file 1_Single-cell and bulk transcriptomic analyses reveal PANoptosis-associated immune dysregulation of fibroblasts in periodontitis.zip by Erli Wu (17785482)

“…</p>Results<p>scRNA-seq analysis revealed a decreased proportion of HGFs alongside enrichment of multiple PANoptosis-related pathways in PD samples. …”

DataSheet2_DYNLT3 overexpression induces apoptosis and inhibits cell growth and migration via inhibition of the Wnt pathway and EMT in cervical cancer.pdf by Jianan Zhang (786459)

“…Up-regulation of DYNLT3 expression significantly inhibited tumor growth in a nude mouse model, while downregulation of DYNLT3 showed the opposite results. …”

DNA damage protecting effects of PEExCC. by Srabonti Saha (17452756)

“…The results demonstrated that higher doses (200 mg) of <i>C. chinense</i> methanol extract inhibited immune responses, whereas lower doses helped restore them. The extracts significantly decreased pro-inflammatory mediators and cytokines in LPS-activated macrophages. …”

Supplementary file 1_Oral bacterial community dynamics during induction of gingival inflammation.docx by Bart J. F. Keijser (16884185)

“…</p>Results<p>The study revealed pronounced microbial changes, particularly in supragingival plaque, where Leptotrichia and Prevotella increased while Streptococcus decreased. Alpha diversity significantly increased in supragingival plaque, tongue, and saliva during gingivitis induction, highlighting shifts in microbial complexity. …”

Table 3_Explainable machine learning reveals ribosome biogenesis biomarkers in preeclampsia risk prediction.xlsx by Jingjing Chen (293564)

“…</p>Results<p>We identified 25 ribosome biogenesis-related differentially expressed genes, which were significantly enriched in RNA degradation and rRNA processing. …”

Table 1_Expression, prognosis and preliminary investigation of the mechanism of action of ACTR6, a member of the ARPs gene family, in hepatocellular carcinoma.docx by Jing Wang (6206297)

“…</p>Results<p>We found that, in addition to ACTR3C, 17 ARPs were significantly overexpressed in HCC compared with normal tissues. …”

Presentation 1_Anti-PD1 therapies induce an early expansion of Ki67+CD8+ T cells in metastatic non-oncogene addicted NSCLC patients.pptx by Alain Gelibter (6409364)

“…Concurrently, 14 soluble immune checkpoints were analyzed by Luminex assay. Immunotherapy significantly increased the levels of Ki67⁺(total and CD8⁺) T cells, PMN(Lox1⁺)-MDSCs, non-suppressive Tregs (nsTregs), and soluble PD1 from T0 to T1 in the entire NSCLC population, while decreased active Tregs. …”

Image 5_A metagenome-wide association study of gut microbiota in hepatitis B virus-related cirrhosis in northwest China.tif by Meirong Feng (22089665)

“…</p>Conclusion<p>HBV-LC patients in Northwest China exhibit altered clinical indicators, gut microbial composition (reduced diversity, increased opportunistic pathogens, decreased beneficial species), and metabolic function. …”

Flexible Microfluidic Devices for Tunable Formation of Double Emulsion by Uditha Roshan (20841937)

“…This innovative approach significantly advances the field of droplet-based microfluidics, providing on-site, real-time tunability for the generation of double-emulsion droplets with high precision and reproducibility.…”

Table 1_Moderating effects of a healthy lifestyle on the association of pre-metabolic syndrome with multiple chronic disease comorbidities.docx by Youqiong Xu (18161893)

“…PreMetS [OR = 1.38, 95%CI: 1.16–1.64] and MetS [OR = 1.61, 95%CI: 1.32–1.97] were associated with a significantly higher risk of multiple comorbidities compared with the normal population, and the risk of multiple comorbidities tended to increase as the number of metabolic disorder components increased (p < 0.001). …”

Glucagon-like peptide-1 receptor agonists, inflammation, and kidney diseases: evidence from Mendelian randomization by Yu-Xuan Yao (21338594)

“…</p> <p>After meta-analyses of both discovery and validation cohorts, genetically proxied GLP1R agonist was found to significantly associated with a decreased risk of diabetic nephropathy (OR = 0.72, 95%CI = 0.54–0.97, <i>p</i> = 0.031) and IgA nephropathy (OR = 0.58, 95%CI = 0.36–0.94, <i>p</i> = 0.027). …”

Data Sheet 1_Dietary resveratrol and β-Hydroxy-β-Methylbutyric acid enhance flavor and modulate intramuscular fat in Tibetan sheep: insights from transcriptomics and lipidomics.zip... by Xuan Chen (158617)

“…Among medium- and long-chain fatty acids, the H-RES-HMB group showed significantly decreased SFAs (C17:0 and C18:0) (p < 0.05) and significantly increased MUFAs (C15:1N5 and C18:1N9) and PUFAs (C18:2N6, C18:3N6, C18:3N3, C20:3N6, and C20:3N3) (p < 0.05). …”

Table 4_Establishment and validation of the prediction model based on lymphocyte subsets for acute kidney injury in sepsis patients.docx by Leyi Wang (408009)

“…On day 1, several lymphocyte subsets were significantly altered in the AKI group, including increased CD4⁺CD38⁺T%, CD8⁺CD38⁺T%, CD155⁺T%, CD4⁺TeM⁺T%, CD8⁺TIGIT⁺T%, and M-MDSC, and decreased CD4⁺LAG3⁺T%, CD4⁺TN⁺T%, and Th17 cells. …”

Table 2_Establishment and validation of the prediction model based on lymphocyte subsets for acute kidney injury in sepsis patients.docx by Leyi Wang (408009)

“…On day 1, several lymphocyte subsets were significantly altered in the AKI group, including increased CD4⁺CD38⁺T%, CD8⁺CD38⁺T%, CD155⁺T%, CD4⁺TeM⁺T%, CD8⁺TIGIT⁺T%, and M-MDSC, and decreased CD4⁺LAG3⁺T%, CD4⁺TN⁺T%, and Th17 cells. …”

Table 5_Establishment and validation of the prediction model based on lymphocyte subsets for acute kidney injury in sepsis patients.docx by Leyi Wang (408009)

“…On day 1, several lymphocyte subsets were significantly altered in the AKI group, including increased CD4⁺CD38⁺T%, CD8⁺CD38⁺T%, CD155⁺T%, CD4⁺TeM⁺T%, CD8⁺TIGIT⁺T%, and M-MDSC, and decreased CD4⁺LAG3⁺T%, CD4⁺TN⁺T%, and Th17 cells. …”

Table 6_Establishment and validation of the prediction model based on lymphocyte subsets for acute kidney injury in sepsis patients.docx by Leyi Wang (408009)

“…On day 1, several lymphocyte subsets were significantly altered in the AKI group, including increased CD4⁺CD38⁺T%, CD8⁺CD38⁺T%, CD155⁺T%, CD4⁺TeM⁺T%, CD8⁺TIGIT⁺T%, and M-MDSC, and decreased CD4⁺LAG3⁺T%, CD4⁺TN⁺T%, and Th17 cells. …”

Table 1_Establishment and validation of the prediction model based on lymphocyte subsets for acute kidney injury in sepsis patients.docx by Leyi Wang (408009)

“…On day 1, several lymphocyte subsets were significantly altered in the AKI group, including increased CD4⁺CD38⁺T%, CD8⁺CD38⁺T%, CD155⁺T%, CD4⁺TeM⁺T%, CD8⁺TIGIT⁺T%, and M-MDSC, and decreased CD4⁺LAG3⁺T%, CD4⁺TN⁺T%, and Th17 cells. …”

Table 3_Establishment and validation of the prediction model based on lymphocyte subsets for acute kidney injury in sepsis patients.docx by Leyi Wang (408009)

“…On day 1, several lymphocyte subsets were significantly altered in the AKI group, including increased CD4⁺CD38⁺T%, CD8⁺CD38⁺T%, CD155⁺T%, CD4⁺TeM⁺T%, CD8⁺TIGIT⁺T%, and M-MDSC, and decreased CD4⁺LAG3⁺T%, CD4⁺TN⁺T%, and Th17 cells. …”

H2AK119ub is neurodevelopmentally enriched within H3K9ac-positive euchromatin. by Aditya Parmar (22331873)

“…(F) Heatmaps depicting H3K9ac CUT&RUN data within loci with no change, increased or decreased H2AK119ub over neurodevelopment. (G) Heatmaps depicting H3K9ac CUT&RUN data within loci harboring both H2AK119ub and H3K27me3. …”

Table1_Surviving septic patients endotyped with a functional assay demonstrate active immune responses.docx by Adam D. Price (19842741)

“…Finally, among septic patients, decreased total TNF and IFNγ expression were associated with 180-day mortality.…”