يعرض 19,761 - 19,780 نتائج من 23,233 نتيجة بحث عن '(( significant ((shape increases) OR (greatest decrease)) ) OR ( significant decrease decrease ))', وقت الاستعلام: 0.62s تنقيح النتائج
  1. 19761

    Image 1_Restoring natural killer cell activity in lung injury with 1,25-hydroxy vitamin D3: a promising therapeutic approach.jpg حسب Johnny Amer (495285)

    منشور في 2025
    "…Isolated lung trNK cells of the ALI mice exhibited reduced CD107a and NKp46 markers and cytotoxicity potentials and were correlated through significantly 2.1-fold higher levels of PD-1 and diminished VDR expressions as compared to naïve mice. …"
  2. 19762

    Supplementary file 4_Development and preliminary clinical feasibility of a Delphi-based aerobic exercise prescription for children with asthma.docx حسب Ying Zhang (40767)

    منشور في 2025
    "…The expert authority coefficient (Cr) was 0.86, and the coefficient of variation (CV) for item importance scores decreased across rounds (from 0.07–0.16 in Round 1 to 0.07–0.13 in Round 2), indicating high expert consensus. …"
  3. 19763

    Data Sheet 1_Preclinical evidence and potential mechanisms of tanshinone ⅡA on cognitive function in animal models of Alzheimer’s disease: a systematic review and meta-analysis.doc... حسب Yuanhang Rong (19207540)

    منشور في 2025
    "…Additionally, it exhibited antiapoptotic effects by increasing the B-cell lymphoma-2/Bcl-2-associated X protein (Bcl-2/Bax) ratio and decreasing Caspase-3 expression. Moreover, treatment improved neuronal/synaptic plasticity by upregulating postsynaptic density-95 (PSD-95) and brain-derived neurotrophic factor (BDNF) levels.…"
  4. 19764

    Datafiles and R script for analyses and figures for submitted manuscript titled: Loss of dominant tree-mycorrhizal mutualism increases soil fungal diversity and alters community st... حسب Lindsay McCulloch (8565423)

    منشور في 2025
    "…Fungal alpha diversity was significantly greater in the OG<sub>100</sub> and OG<sub>50</sub> compared to the control, largely driven by decreased ECM abundance and increased saprophytic fungal abundance in OG<sub>100</sub> and OG<sub>50</sub>. …"
  5. 19765

    Table 6_Immune-related diagnostic indicators and targeted therapies for COPD combined with NASH were identified and verified via WGCNA and LASSO.xlsx حسب Jianwei Hong (6918776)

    منشور في 2025
    "…Introduction<p>The incidence of chronic obstructive pulmonary disease (COPD) and non-alcoholic fatty liver disease (NAFLD) has increased significantly in past decades, posing a significant public health burden. …"
  6. 19766

    Table 1_Elucidating the causal relationship between 486 genetically predicted blood metabolites and the risk of gastric cancer: a comprehensive Mendelian randomization analysis.xls... حسب Lei Qian (292302)

    منشور في 2024
    "…</p>Results<p>The MVMR analysis revealed a significant association between genetically predicted elevated levels of tryptophan (odds ratio [OR] = 0.523, 95% confidence interval [CI] = 0.313–0.872, p = 0.013), nonadecanoate (19:0) (odds ratio [OR] = 0.460, 95% confidence interval [CI] = 0.225–0.943, p = 0.034), and erythritol (odds ratio [OR] = 0.672, 95% confidence interval [CI] = 0.468–0.930, p = 0.016) with a decreased risk of gastric cancer. …"
  7. 19767

    Table 1_Time trends in mechanical thrombectomy (2017–2021): do real-world data reflect advances in evidence?.docx حسب Christoph Riegler (3554054)

    منشور في 2025
    "…The use of intravenous thrombolysis decreased (52.4% to 40.4%; p<sub>trend</sub><0.01). …"
  8. 19768

    Table 2_Immune-related diagnostic indicators and targeted therapies for COPD combined with NASH were identified and verified via WGCNA and LASSO.xlsx حسب Jianwei Hong (6918776)

    منشور في 2025
    "…Introduction<p>The incidence of chronic obstructive pulmonary disease (COPD) and non-alcoholic fatty liver disease (NAFLD) has increased significantly in past decades, posing a significant public health burden. …"
  9. 19769

    Table 1_TCF3 downregulation alleviates renal fibrosis via PI3K/Akt/mTOR pathway inhibition and autophagy restoration in diabetic nephropathy.docx حسب Chen-xiao Liu (22750118)

    منشور في 2025
    "…Both the DN rat model and HG-stimulated HK-2 cells exhibited enhanced EMT markers, with significantly increased α-SMA and vimentin expression (p < 0.001), and decreased E-cadherin levels (p < 0.001). …"
  10. 19770

    A Locally Linear Dynamic Strategy for Manifold Learning. حسب Weifan Wang (4669081)

    منشور في 2025
    "…In contrast to alignment modulation, the change in the spectrum is largely non-selective. exhibits no significant change for both signal-oriented (blue) and noise-oriented (orange) modes. …"
  11. 19771

    Table 1_Repertoire-based mapping and time-tracking of T helper cell subsets in scRNA-Seq.xlsx حسب Daniil K. Lukyanov (20997755)

    منشور في 2025
    "…Introduction<p>The functional programs of CD4<sup>+</sup> T helper (Th) cell clones play a central role in shaping immune responses to different challenges. …"
  12. 19772

    Data Sheet 1_Repertoire-based mapping and time-tracking of T helper cell subsets in scRNA-Seq.pdf حسب Daniil K. Lukyanov (20997755)

    منشور في 2025
    "…Introduction<p>The functional programs of CD4<sup>+</sup> T helper (Th) cell clones play a central role in shaping immune responses to different challenges. …"
  13. 19773

    Data_Sheet_1_The effect of cumulative exposure with unhealthy lifestyles on the H-type hypertension among Chinese adults: a community-based, propensity-score-matched, and case–cont... حسب Ling Li (38566)

    منشور في 2024
    "…Notably, there was a monotonically increasing curve (J-shaped) relationship between unhealthy lifestyles and the risk of HTH (p = 0.014).…"
  14. 19774

    <b>Nonlinear and Sex-Specific Associations of Vitamin D Metabolites with Inflammatory Blood Markers in 455,000 Adults</b> حسب XIN CHEN (10031207)

    منشور في 2025
    "…Neutrophil counts were lowest at 25(OH)D levels of ~40–60 nmol/L and increased significantly at both lower and higher extremes (p < 0.001). …"
  15. 19775

    <b>Nonlinear and Sex-Specific Associations of Vitamin D Metabolites with Inflammatory Blood Markers in 455,000 Adults</b>Item حسب XIN CHEN (10031207)

    منشور في 2025
    "…Neutrophil counts were lowest at 25(OH)D levels of ~40–60 nmol/L and increased significantly at both lower and higher extremes (p < 0.001). …"
  16. 19776

    <b>Distributed Hydraulic Micro-Cooling (MHD): A Low-Cost, High-Impact Urban Heat Mitigation Strategy</b> / <b>Enfriamiento Hidráulico Micro-Distribuido (MHD): Estrategia Urbana de... حسب Ricardo Riveros (22484566)

    منشور في 2025
    "…Large thermal masses such as roofs, asphalt roads, and concrete structures store significant amounts of solar radiation during the day (up to 1200–1600 MJ/m²). …"
  17. 19777

    DataSheet_1_Maternal and neonatal immune response to SARS-CoV-2, IgG transplacental transfer and cytokine profile.docx حسب Rocío Rubio (513839)

    منشور في 2025
    "…Our results show that SARS-CoV-2 infection during the third trimester of pregnancy induces a robust antibody and cytokine response at delivery and causes a significant reduction of the SARS-CoV-2-specific IgGs transplacental transfer, with a stronger negative effect when the infection is closer to delivery.…"
  18. 19778

    Image 1_Differential Ca2+ handling by isolated synaptic and non-synaptic mitochondria: roles of Ca2+ buffering and efflux.tif حسب Jyotsna Mishra (3703195)

    منشور في 2025
    "…When both mitochondrial fractions were exposed to increasing mCa<sup>2+</sup> loads we observed decreased mCa<sup>2+</sup> sequestration in synaptic mitochondria as assessed by a significant increase in the steady-state free extra matrix Ca<sup>2+</sup> (ss[Ca<sup>2+</sup>]<sub>e</sub>) compared to non-synaptic mitochondria. …"
  19. 19779

    Cued-attention is mediated by a cholinergic HDB to SAC circuit. حسب Rahul Garg (3064578)

    منشور في 2025
    "…Inset denotes glomeruli with significant changes with SAC inhibition. Yellow: increased, dark grey: decreased, light grey: unchanged. …"
  20. 19780

    Revisiting the association between sodium-glucose cotransporter-2 inhibitors and the risk of neoplasm in patients with type 2 diabetes: new insights from an updated systematic revi... حسب Yiran Wang (1492303)

    منشور في 2025
    "…</p> <p>A total of 53 RCTs with 126,232 participants were included. No significant differences were found for the risk of overall neoplasm (RR = 1.08, 95% CI: 0.99 to 1.19, I<sup>2</sup> = 23%) in patients with SGLT-2i treatment compared with non-users. …"